Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P05231 (interleukin-6)
 23,907 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

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Human Gene/Protein
CDK5 regulatory subunit associated protein 1 10.4
NADH-ubiquinone oxidoreductase B18 subunit 10.4
LOC286367 10.4
epsin 2a 10.4
SNRNP27 10.4
coagulation factor X precursor 10.4
SBNO2 protein 10.4
proliferation-inducing ligand APRIL 10.4
HASJ4442 10.4
Bcd orf1 10.4
Pellino-3 10.4
Ubiquitin-fold modifier conjugating enzyme 1 10.4
interleukin-6 10.4
gp130-like monocyte receptor 9.4
MHC class I HLA-B 9.4
TNFR1B 9.4
NaGLT1 9.4
human leucocyte antigen A 9.4
AP3M2 9.4
feline leukemia virus subgroup C cellular receptor 1 9.4
PRGA 9.4
RBM33 9.4
DAZ-associated protein 1 9.4
hematopoietin-1 9.4
TCF5 9.4
Sma- and Mad-related protein 1 9.4
IL6 protein 9.3
LPAAT-alpha 9.1
Oncostatin-M 8.9
MAGEE1 8.8
Chemokine (C-C motif) ligand 21 8.8
UNC119B 8.8
HSM-2 8.8
Meteorin-like protein 8.8
TI60 8.8
protein kinase C and casein kinase substrate in neurons 1 8.8
TDRD10 8.8
inducible nitric oxidase synthase 8.8
Myelin-oligodendrocyte glycoprotein 8.8
APRF 8.8
fucosyltransferase 11 8.8
ZC3H12B 8.8
sIL-6R 8.7
gp130 8.7
Gp130 8.5
Cess 8.4
interferon-gamma receptor alpha chain 8.4
transcription factor SP3 8.4
SH3GL1 8.4
FBXO17 8.4
CLCP1 8.4
MEK kinase 4 8.4
MLCK2 8.4
Radioprotective 105 kDa protein 8.4
STNO 8.4
DDH1 8.4
cardiotrophin-1 8.3
Oncostatin M 8.2
FUT11 8.1
SCM-1beta 8.1
MRPL38 8.1
endothelial-overexpressed lipopolysaccharide-associated factor 1 8.1
DUB-3 8.1
NECAP2 8.1
Zinc finger protein A20 8.1
WBP-1 8.1
Galanin receptor 2 8.1
suppressor of cytokine signaling 4 8.1
endothelial adhesion molecule 1 8.1
TMEM57 8.1
Apobec-1 complementation factor 8.1
rpL23 8.1
oncostatin M 8.1
Toll-interleukin 1 receptor domain-containing adaptor protein 7.9
ZC3H12D 7.9
CNTFR 7.9
leukemia inhibitory factor receptor 7.8
Tec protein tyrosine kinase 7.8
APELIN 7.8
Cardiotrophin 1 7.8
more...
Disease
Acute idiopathic urticaria 10.4
Idiopathic plasmacytic lymphadenopathy 10.4
Habronemosis 10.4
Acute left-sided heart failure 10.4
Anion gap acidosis 9.4
Chronic epididymitis 8.8
Juvenile polyarteritis 8.8
Drug-induced uveitis 8.4
Staphylococcus aureus toxic shock syndrome 8.4
Tying-up 8.4
Renal hematuria 8.4
Rapidly progressive periodontitis 8.4
Erythrocytopenia 8.1
ROCA 8.1
Steroid withdrawal syndrome 8.1
Bronchial infection 7.8
multicentric Castleman's disease 7.7
Progressive massive fibrosis 7.6
Congenital thrombocytopenia 7.6
Influenza encephalopathy 7.6
Streptococcal meningitis 7.6
Sensorimotor polyneuropathy 7.6
Funisitis 7.6
Systemic juvenile idiopathic arthritis 7.4
urination disorder 7.4
Juvenile psoriatic arthritis 7.4
stage III multiple myeloma 7.2
Chronic tophaceous gout 7.2
Tumor embolus 7.2
Cytokine release syndrome 7.2
Coliform mastitis 7.1
Castleman's disease 7.0
SPH2 6.9
Infectious peritonitis 6.9
chronic tracheitis 6.9
Primary cutaneous plasmacytoma 6.9
malignant myeloma 6.9
Acute peritonitis 6.9
Renal vasculitis 6.8
monosomy 16q 6.8
Cytophagic histiocytic panniculitis 6.8
Stauffer's syndrome 6.8
Adenomatous goiter 6.8
Secondary biliary cirrhosis 6.8
Edematous pancreatitis 6.6
OID 6.6
mediastinal cancer 6.6
plasmacytosis 6.5
Leishmania mexicana complex 6.5
Decompensated heart failure 6.5
Gastrointestinal mucositis 6.5
HPC4 6.5
Multiple symmetrical lipomatosis 6.5
postlaminectomy syndrome 6.4
Chronic idiopathic neutropenia 6.4
postperfusion syndrome 6.4
Amiodarone-induced thyrotoxicosis 6.3
Stenotrophomonas maltophilia infection 6.3
Herpes simplex 1 6.2
Ehlers-Danlos syndrome type II 6.2
histiocytic leukemia 6.2
Subacute combined degeneration 6.2
Neonatal calf diarrhea 6.1
metabolic syndrome X 6.1
Fowl cholera 6.1
AKE 6.1
Inflammation of the central nervous system 6.1
PanIN-1B 6.1
Cytokine storm 6.1
Mesangioproliferative glomerulonephritis 6.1
Coronary arteritis 6.1
Progression of prostate cancer 6.1
polyclonal hypergammaglobulinemia 6.0
MYP3 6.0
Cancer cachexia 5.9
Adult growth hormone deficiency 5.9
Systemic inflammatory response syndrome (SIRS) 5.9
GGF2 5.9
anemia of chronic disease 5.8
Canine leptospirosis 5.8
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Symptom
Afebrile convulsion 10.4
Genitourinary pain 10.4
feeling of malaise 7.6
Pancreatic pain 7.6
Chronic intractable pain 7.4
SLE-like symptoms 7.2
Local swelling 6.7
cardiovascular disability 6.6
Stable angina pectoris 6.2
Cancer Fatigue 5.7
Hangover 5.7
Flu-like symptoms 5.6
sinus pain 5.5
sinus headache 5.3
Muscle soreness 5.2
painful erections 5.2
cachexia 5.1
Induced hypothermia 4.7
Severe diarrhea 4.6
Grimace 4.3
renal pain 4.3
lassitude 4.2
Inflammatory pain 4.2
disturbed balance 4.1
Neuropathic pain 4.1
physical exhaustion 4.0
lumbar back pain 4.0
skin damage 3.9
Positive and Negative Symptoms 3.8
Nasal symptoms 3.7
polymyalgia 3.5
stump pain 3.5
night sweats 3.3
swollen joints 3.3
mental fatigue 3.2
iliac fossa pain 3.1
autodigestion 3.1
acute stress 3.0
scaly skin 3.0
throat irritation 2.9
precordial pain 2.9
POA 2.9
hangover 2.9
respiratory distress 2.9
hepatosplenomegaly 2.9
anorexia 2.9
Tenderness 2.8
rectal pain 2.8
catarrh 2.8
hyperoxia 2.8
Gastrointestinal symptoms 2.8
bladder pain 2.8
despair 2.7
myalgia 2.7
arthralgia 2.7
rigors 2.7
overweight 2.7
inanition 2.6
chills 2.5
splenomegaly 2.5
Depressive symptoms 2.4
bone pain 2.4
male subfertility 2.3
acute low back pain 2.3
decreased appetite 2.2
exhaustion 2.2
clubbing 2.2
persistent cough 2.1
hypothermia 2.1
menopausal symptoms 2.0
fatigue 2.0
limb pain 2.0
Poor sleep 1.9
prostration 1.8
loss of taste 1.8
dry eye 1.8
nasal congestion 1.8
sciatica 1.8
intestinal bleeding 1.7
lethargy 1.7
more...
Drug
Caprylic Acid 10.4
Denagard 10.4
ThG 9.4
Tocilizumab 8.8
Romurtide 8.2
Serrapeptase 8.1
Typhoid vaccine 7.9
Platycodon root 7.8
Camellia oil 7.6
Cetraxate hydrochloride 7.4
Angelica dahurica root 7.2
Tenidap 7.2
Remifentanyl 6.9
Oyster shell 6.9
E5564 6.8
Flurbiprofen axetil 6.7
Centoxin 6.7
IL-11 6.6
Iodosorb 6.6
Platonin 6.5
Bonefos 6.3
Idoxifene 6.2
Safingol 6.2
Lipoic Acid 5.9
Sivelestat 5.8
Sivelestat sodium hydrate 5.8
Gabexate mesilate 5.7
1-Deoxynojirimycin 5.7
Tepoxalin 5.7
Lisofylline 5.6
AKM 5.6
Ferumoxtran-10 5.6
Ulinastatin 5.5
Adenosine Monophosphate 5.5
Imagent 5.4
Esculin 5.4
Abatacept 5.3
Dextran sulfate sodium 5.3
Aescin 5.3
Spiriva 5.3
Benfotiamine 5.3
Icodextrin 5.2
Drotrecogin alfa 5.1
Paxil 5.1
Drotrecogin alfa 5.1
Tolfenamic acid 5.0
Roflumilast 4.9
Roflumilast 4.9
fluphenazine dihydrochloride 4.9
Rocaltrol 4.9
Paxil 4.9
Rapamune 4.9
Paxil 4.9
Benzofuran 4.8
Platelet Activating Factor 4.8
Florfenicol 4.8
Aredia 4.8
Anakinra 4.7
Coconut oil 4.7
Zileuton 4.7
Silodosin 4.7
Emodin 4.7
2-Methoxyestradiol 4.6
Azelnidipine 4.6
Red ginseng 4.5
IFN-beta 4.5
PAPM/BP 4.4
Butaprost 4.4
Nafamostat mesilate 4.4
Maraviroc 4.4
Dopexamine 4.4
Flunixin 4.4
Emodin 4.4
Fennel 4.3
BLyS 4.3
Tiopronin 4.3
Simvastatin 4.3
Olmesartan 4.3
Zebularine 4.3
Revlimid 4.3
more...
Enzyme
kallikrein 10 6.6
glucosaminyl 3-O-sulfotransferase 6.4
glucosaminyl 3-O-sulfotransferase 6.4
Cypridina luciferase 6.2
ecdysone oxidase 6.1
dTDP-glucose 4,6-dehydratase 6.1
1-acylglycerol-3-phosphate O-acyltransferase 5.8
25-hydroxyvitamin D3 1alpha-hydroxylase 5.7
collagenase 3 5.4
neurosin 5.3
matrix metalloproteinase 10 5.3
putrescine oxidase 5.2
GGGT 5.1
thrombin-activatable fibrinolysis inhibitor 4.7
IKK 4.7
Lys-gingipain 4.6
BBE 4.6
LMT 4.6
serum carnosinase 4.5
MIP 4.4
MMP-3 4.4
D-dopachrome tautomerase 4.4
serralysin 4.2
endo-alpha-N-acetylgalactosaminidase 4.2
matriptase 4.2
pseudolysin 4.2
glutathione peroxidase 4.1
AMP-activated kinase 4.1
aspartate aminotransferase 4.1
interstitial collagenase 4.1
alanine aminotransferase 4.1
mitogen-activated protein kinase 4.0
5-oxoprolinase 4.0
matrix metalloproteinase 14 3.9
superoxide dismutase 3.9
neutrophil elastase 3.9
caspase-4 3.9
factor C 3.9
glucosidase II 3.9
STK2 3.9
heme oxygenase 3.8
nicotinamide N-methyltransferase 3.8
indoleamine 2,3-dioxygenase 3.8
3-oxoacid CoA-transferase 3.8
CDP-diacylglycerol synthase 3.8
creatine kinase 3.8
TACE 3.7
matrix metalloproteinase 9 3.7
matriptase 3.7
adenine deaminase 3.7
NO synthase 3.7
caspase-4 3.7
chloramphenicol acetyltransferase 3.7
arginase 3.6
aminopeptidase P 3.6
paraoxonase 3.6
lactate dehydrogenase 3.6
HK2 3.6
rhomboid protease 3.6
chymase 3.6
RGP 3.6
alpha-methylacyl-CoA racemase 3.5
mu-calpain 3.5
inositol 3-kinase 3.5
carnosinase 3.4
AMP-activated protein kinase 3.4
cathepsin K 3.4
nicotinamide phosphoribosyltransferase 3.4
sphingosine kinase 3.4
cathepsin S 3.4
caspase-3 3.4
20alpha-hydroxysteroid dehydrogenase 3.4
collagenase 3.4
HOA 3.4
homoserine kinase 3.4
paraoxonase 3.3
caspase-1 3.3
PWD 3.3
SPT 3.3
p80 3.3
more...
Compound
C6H10O7 10.4
C21H30O 10.4
Evoxine 10.4
C6H10O7 10.4
C21H30O 10.4
C6H10O7 10.4
4,4-dimethylproline 10.4
C21H30O 9.4
C40H56O 9.4
C40H56O 9.4
C40H56O 9.4
alpha-D-Galacturonic acid 9.4
C40H56O 9.4
C40H54O 9.4
C6H10O7 9.4
Robinin 9.1
Robinin 9.1
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
Lycopodine 8.8
C10H18O 8.8
L-Guluronic acid 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
3-chloro-4-hydroxybenzoic acid 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
o-Cresolphthalein complexone 8.8
hex-2-ulosonic acid 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
Trifolirhizin 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
C10H18O 8.8
Chelidonic acid 8.4
C10H18O 8.4
LG 100268 8.4
C10H18O 8.4
C10H18O 8.4
C10H18O 8.4
C10H18O 8.4
Catalposide 8.4
C10H18O 8.4
2-Keto-D-gluconic acid 8.4
C10H18O 8.4
D-Mannuronic acid 8.4
Didecyldimethylammonium chloride 8.3
Tetrahydrocoptisine 8.1
Taraxasterol 8.1
Apigetrin 7.9
more...