Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UNIPROT:P05231 (interleukin-6)
23,907 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein interleukin-6 23907 tumor necrosis factor 6485 cytokine 5965 TNF 3118 lipopolysaccharide 2456 C-reactive protein 2194 Sep 1620 IL-6 1337 Mol 1228 tumor necrosis factor alpha 1223 insulin 1070 interferon 852 inducible nitric oxide synthase 764 interferon-gamma 680 interleukin-10 679 STAT3 674 cyclooxygenase-2 668 gp130 658 superoxide dismutase 628 IL-8 607 Cytokine 598 p65 573 p38 569 collagen 535 vascular endothelial growth factor 515 leptin 491 IL-10 490 TLR4 480 IL-1 beta 476 monocyte chemoattractant protein-1 463 adiponectin 463 LPS 456 IL-1 440 IFN 416 myeloperoxidase 411 interleukin-2 407 fibrinogen 406 signal transducer and activator of transcription 3 397 TNF-alpha 386 chemokine 353 more...

Disease cancer 1799 tumor 1550 obesity 766 diabetes 724 sepsis 654 sepsis 636 multiple myeloma 626 rheumatoid arthritis 610 atherosclerosis 609 cardiovascular disease 414 hypertension 398 depression 389 arthritis 372 hepatocellular carcinoma 363 ischemia 350 type 2 diabetes 338 GSH 306 Alzheimer's disease 302 leukemia 285 stroke 274 tumor growth 272 breast cancer 262 HIV 226 metabolic syndrome 225 lymphoma 217 myocardial infarction 215 carcinoma 203 infectious diseases 202 prostate cancer 194 heart failure 194 anemia 193 virus infection 191 plaque 185 osteoporosis 181 tumorigenesis 174 osteoarthritis 173 colitis 173 immunodeficiency 171 pneumonia 169 carcinogenesis 166 more...

Symptom pain 404 fatigue 155 cachexia 146 anesthesia 129 overweight 125 respiratory distress 108 seizures 82 anorexia 75 diarrhea 62 hypothermia 56 exhaustion 46 headache 46 cough 44 splenomegaly 41 angina 41 arthralgia 35 collapse 34 myalgia 32 functional recovery 31 abdominal pain 29 starvation 29 analgesia 28 hyperoxia 27 acute stress 27 nausea 26 erythema 26 vomiting 26 weakness 25 sleepiness 24 hepatosplenomegaly 24 dyspnea 23 chills 18 Neuropathic pain 18 skin damage 17 Ill 15 insomnia 15 lethargy 14 bone pain 12 back pain 10 thinning 10 more...

Drug CSF 244 IL-2 173 Tocilizumab 143 Dermatol 140 IFN-gamma 137 Cardiovasc 116 IL-11 81 ROS 70 Monit 61 lysine 58 ascorbate 52 IFN-beta 52 Dial 50 G-CSF 48 vitamin E 47 Gel 42 MAP 40 Angiotensin II 32 PTH 30 p75 29 Bifidobacterium 27 Indomethacin 25 ROC 24 Simvastatin 24 Nephron 23 CTX 22 ICI 21 Heme 20 Ethanol 20 Histamine 19 caffeine 18 Albumin 18 EPA 17 CCL 16 IL-1ra 16 Estrogens 13 CTX 13 ZnO 13 Nitric Oxide 13 Nephron 13 more...

Enzyme mitogen-activated protein kinase 1173 superoxide dismutase 668 peroxidase 473 catalase 356 alanine aminotransferase 336 protein kinase 311 ERK 308 focal adhesion kinase 301 glutathione peroxidase 291 caspase-3 286 aspartate aminotransferase 277 lactate dehydrogenase 273 alkaline phosphatase 244 luciferase 235 protein kinase C 214 creatine kinase 191 reverse transcriptase 156 NO synthase 154 collagenase 143 thrombin 142 MEK 129 AMP-activated protein kinase 106 IKK 95 renin 85 proteasome 84 MIP 80 RNA polymerase 79 phosphatidylinositol 3-kinase 76 phospholipase A2 70 elastase 66 NADPH oxidase 66 trypsin 65 transcriptase 64 NADPH oxidase 63 glutathione reductase 58 acetylcholinesterase 55 MMP-3 54 APC 51 tissue plasminogen activator 50 glutathione S-transferase 50 more...

Compound TNF 3118 Dec 1657 nitric oxide 1239 DNA 1222 Clin 1100 glucose 1020 oxygen 1008 water 462 calcium 454 tyrosine 386 sodium 361 acetate 332 GSH 314 GSH 314 creatinine 303 iron 264 ethanol 241 sulfate 221 urea 218 phosphate 202 nitrogen 194 PGE 179 Cardiol 178 THP 174 arginine 173 cAMP 171 THP 171 serine 138 zinc 131 MTT 131 hydrogen 122 MDA 120 galactose 117 AMP 117 Insulin 116 cysteine 108 ATP 99 glutamate 97 alanine 96 vitamin D 94 more...

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