Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P05231 (
interleukin-6
)
23,907
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
interleukin-6
23907
tumor necrosis factor
6485
cytokine
5965
TNF
3118
lipopolysaccharide
2456
C-reactive protein
2194
Sep
1620
IL-6
1337
Mol
1228
tumor necrosis factor alpha
1223
insulin
1070
interferon
852
inducible nitric oxide synthase
764
interferon-gamma
680
interleukin-10
679
STAT3
674
cyclooxygenase-2
668
gp130
658
superoxide dismutase
628
IL-8
607
more...
Disease
cancer
1799
tumor
1550
obesity
766
diabetes
724
sepsis
654
sepsis
636
multiple myeloma
626
rheumatoid arthritis
610
atherosclerosis
609
cardiovascular disease
414
hypertension
398
depression
389
arthritis
372
hepatocellular carcinoma
363
ischemia
350
type 2 diabetes
338
GSH
306
Alzheimer's disease
302
leukemia
285
stroke
274
more...
Symptom
pain
404
fatigue
155
cachexia
146
anesthesia
129
overweight
125
respiratory distress
108
seizures
82
anorexia
75
diarrhea
62
hypothermia
56
exhaustion
46
headache
46
cough
44
angina
41
splenomegaly
41
arthralgia
35
collapse
34
myalgia
32
functional recovery
31
starvation
29
more...
Drug
CSF
244
IL-2
173
Tocilizumab
143
Dermatol
140
IFN-gamma
137
Cardiovasc
116
IL-11
81
ROS
70
Monit
61
lysine
58
IFN-beta
52
ascorbate
52
Dial
50
G-CSF
48
vitamin E
47
Gel
42
MAP
40
Angiotensin II
32
PTH
30
p75
29
more...
Enzyme
mitogen-activated protein kinase
1173
superoxide dismutase
668
peroxidase
473
catalase
356
alanine aminotransferase
336
protein kinase
311
ERK
308
focal adhesion kinase
301
glutathione peroxidase
291
caspase-3
286
aspartate aminotransferase
277
lactate dehydrogenase
273
alkaline phosphatase
244
luciferase
235
protein kinase C
214
creatine kinase
191
reverse transcriptase
156
NO synthase
154
collagenase
143
thrombin
142
more...
Compound
TNF
3118
Dec
1657
nitric oxide
1239
DNA
1222
Clin
1100
glucose
1020
oxygen
1008
water
462
calcium
454
tyrosine
386
sodium
361
acetate
332
GSH
314
GSH
314
creatinine
303
iron
264
ethanol
241
sulfate
221
urea
218
phosphate
202
more...