Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P05231 (interleukin-6)
23,907 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
interleukin-6 23907
tumor necrosis factor 6485
cytokine 5965
TNF 3118
lipopolysaccharide 2456
C-reactive protein 2194
Sep 1620
IL-6 1337
Mol 1228
tumor necrosis factor alpha 1223
insulin 1070
interferon 852
inducible nitric oxide synthase 764
interferon-gamma 680
interleukin-10 679
STAT3 674
cyclooxygenase-2 668
gp130 658
superoxide dismutase 628
IL-8 607
more...
Disease
cancer 1799
tumor 1550
obesity 766
diabetes 724
sepsis 654
sepsis 636
multiple myeloma 626
rheumatoid arthritis 610
atherosclerosis 609
cardiovascular disease 414
hypertension 398
depression 389
arthritis 372
hepatocellular carcinoma 363
ischemia 350
type 2 diabetes 338
GSH 306
Alzheimer's disease 302
leukemia 285
stroke 274
more...
Symptom
pain 404
fatigue 155
cachexia 146
anesthesia 129
overweight 125
respiratory distress 108
seizures 82
anorexia 75
diarrhea 62
hypothermia 56
exhaustion 46
headache 46
cough 44
angina 41
splenomegaly 41
arthralgia 35
collapse 34
myalgia 32
functional recovery 31
starvation 29
more...
Drug
CSF 244
IL-2 173
Tocilizumab 143
Dermatol 140
IFN-gamma 137
Cardiovasc 116
IL-11 81
ROS 70
Monit 61
lysine 58
IFN-beta 52
ascorbate 52
Dial 50
G-CSF 48
vitamin E 47
Gel 42
MAP 40
Angiotensin II 32
PTH 30
p75 29
more...
Enzyme
mitogen-activated protein kinase 1173
superoxide dismutase 668
peroxidase 473
catalase 356
alanine aminotransferase 336
protein kinase 311
ERK 308
focal adhesion kinase 301
glutathione peroxidase 291
caspase-3 286
aspartate aminotransferase 277
lactate dehydrogenase 273
alkaline phosphatase 244
luciferase 235
protein kinase C 214
creatine kinase 191
reverse transcriptase 156
NO synthase 154
collagenase 143
thrombin 142
more...
Compound
TNF 3118
Dec 1657
nitric oxide 1239
DNA 1222
Clin 1100
glucose 1020
oxygen 1008
water 462
calcium 454
tyrosine 386
sodium 361
acetate 332
GSH 314
GSH 314
creatinine 303
iron 264
ethanol 241
sulfate 221
urea 218
phosphate 202
more...