Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P05109 (S100A8)
1,212 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
S100A8 1212
S100A9 551
S100 230
Mol 119
S100A12 104
cytokine 95
TLR4 93
Sep 75
IL-6 68
TNF 65
IL-8 48
S100A7 45
NIF 43
MRP8 42
chemokine 39
calcium-binding protein 39
MRP14 39
lipopolysaccharide 38
Smad3 36
defensin 35
IL-10 32
p38 30
CD11b 30
S100A6 29
RAGE 29
LPS 28
S100A4 28
tumor necrosis factor 27
myeloperoxidase 27
IL-17 27
TGF-beta 26
collagen 25
MAPK 25
CD14 25
CXCL1 25
S100A11 24
S100A1 24
CCL2 23
S100B 23
C-reactive protein 21
MMP9 20
Smad2 20
S100A10 19
STAT3 19
CD4 18
S100A2 17
CD68 17
interferon 17
receptor for advanced glycation end-products 17
activin 17
IL-1 16
IL1B 16
IFN 16
IL-22 16
lymphoid 16
Pseudomonas 16
granulocyte 15
plasminogen activator inhibitor-1 15
TOF 15
p53 14
transforming growth factor-beta 14
MMP1 13
CCL20 13
TLR2 13
CXCL2 13
insulin 13
RANTES 12
inducible nitric oxide synthase 12
S100P 12
HLA-DR 12
high mobility group box 1 12
p65 12
histone 12
matrix metalloproteinase 11
Smad7 11
THP 11
gut 11
glycoprotein 11
albumin 11
MyD88 11
more...
Disease
cancer 164
tumor 151
psoriasis 43
breast cancer 42
rheumatoid arthritis 33
carcinoma 32
arthritis 28
atherosclerosis 28
carcinogenesis 26
tumorigenesis 25
tumor growth 25
tumor progression 24
melanoma 24
metastases 22
sepsis 22
sepsis 22
asthma 20
plaque 19
dermatitis 19
diabetes 19
obesity 18
skin disease 18
squamous cell carcinoma 17
colitis 15
cardiovascular disease 15
chronic obstructive pulmonary disease 15
osteoarthritis 15
Alzheimer's disease 15
leukemia 14
cystic fibrosis 14
atopic dermatitis 14
hepatocellular carcinoma 13
adenocarcinoma 13
inflammatory bowel disease 13
colorectal cancer 13
prostate cancer 12
SDS 11
myocardial infarction 11
periodontitis 10
bladder cancer 10
Crohn's disease 10
stroke 10
type 2 diabetes 10
systemic lupus erythematosus 9
primary tumor 9
bacterial infection 9
autoimmune disease 9
Mycobacterium 8
skin cancer 8
infectious diseases 8
lung cancer 8
malaria 8
colon cancer 8
glomerulonephritis 7
lymphoma 7
MIP 7
synovitis 7
pancreatic cancer 7
acute myeloid leukemia 7
gastric cancer 7
HIV 7
ovarian cancer 6
dysplasia 6
vasculitis 6
transitional cell carcinoma 6
keratitis 6
ischemia 6
uterus 6
aggressiveness 6
MCF 6
Vulvovaginal candidiasis 5
myeloproliferative disorders 5
immunopathology 5
periodontal disease 5
adenoma 5
myelodysplastic syndrome 5
lung disease 5
tuberculosis 5
hyperglycemia 5
myocardial ischemia 5
more...
Symptom
pain 7
dry eye 4
erythema 4
starvation 4
diarrhea 3
Gastrointestinal symptoms 1
halitosis 1
exhaustion 1
respiratory distress 1
wheezing 1
skin damage 1
back pain 1
abdominal pain 1
chest pain 1
hepatomegaly 1
discomfort 1
Fluctuation 1
hypothermia 1
Scratch 1
microbial colonization 1
scaly skin 1
discomfort 1
muscle cramps 1
fever of unknown origin 1
functional recovery 1
weakness 1
Drug
Dermatol 31
CSF 9
IFN-gamma 7
G-CSF 7
ROS 6
ROC 5
Monit 4
Gel 4
IL-2 4
Activin 3
Retinoic acid 3
MAP 3
Cardiovasc 2
Imiquimod 2
GEO 2
Glutathione 2
p75 2
MRC 2
lysine 2
Asthma 2
Fulvestrant 1
Doxycycline 1
CTX 1
Pronase 1
ADM 1
Adriamycin 1
Prednisolone 1
Tocilizumab 1
uPA 1
NADH 1
Methylprednisolone 1
Glucagon 1
Camp 1
Angiotensin II 1
PTH 1
CTC 1
IL-1ra 1
PDL 1
Rutin 1
NOV 1
IFN-beta 1
Forskolin 1
-deoxyadenosine 1
CTC 1
Taxol 1
CIA 1
CTX 1
TiO2 1
Albumin 1
Ferumoxytol 1
Allergen 1
CTX 1
ABC 1
Enzyme
mitogen-activated protein kinase 46
ERK 37
luciferase 34
peroxidase 29
trypsin 16
NADPH oxidase 12
NADPH oxidase 12
protein kinase C 10
collagenase 10
dihydrofolate reductase 9
protein kinase 8
lysozyme 8
glutathione S-transferase 7
focal adhesion kinase 7
MIP 7
alkaline phosphatase 7
reverse transcriptase 6
caspase-3 5
lactate dehydrogenase 5
arginase 5
superoxide dismutase 5
caspase-1 4
alanine aminotransferase 4
MMP-3 4
NO synthase 4
neutrophil elastase 3
SNO 3
MAP 3
cathepsin D 3
dihydropteroate synthase 3
alpha-amylase 3
NOS 3
glutathione peroxidase 3
catalase 3
urokinase-type plasminogen activator 3
matrix metalloproteinase 2 3
aspartate aminotransferase 3
elastase 3
chitinase 3
ATP synthase 3
lipase 3
NQO1 2
calcineurin 2
TMT 2
chloramphenicol acetyltransferase 2
heparinase 2
proteinase K 2
cathepsin L 2
ACE 2
cathepsin B 2
proteasome 2
RNase 2
lysyl oxidase 2
ceruloplasmin 2
indoleamine 2,3-dioxygenase 2
MMP 2
phospholipase A2 2
RNase 2
P-glycoprotein 2
furin 2
renin 2
GSK 2
BAL 2
plasmin 2
peroxiredoxin 2
proteinase-3 2
TACE 2
transglutaminase 2
AMP-activated protein kinase 1
transaldolase 1
ALA synthase 1
acid phosphatase 1
enolase 1
MEK 1
thrombin 1
tryptase 1
caspase-4 1
Omi/HtrA2 1
AST 1
acyl-CoA dehydrogenase 1
more...
Compound
calcium 195
DNA 90
Dec 88
TNF 65
Clin 45
zinc 43
oxygen 38
sodium 23
His 19
water 18
sulfate 18
methionine 16
manganese 15
TOF 15
acetate 14
glucose 12
retinoic acid 12
THP 11
nitric oxide 11
THP 11
cysteine 10
copper 10
alanine 10
SDS 10
PMA 9
PMA 8
ATP 7
Asp 7
hydrogen 6
iron 6
serine 6
ClO 6
creatinine 6
phosphate 5
ethanol 5
cAMP 5
silver 5
leucine 4
DBA 4
PGE 4
lysine 4
threonine 4
PGE2 3
H2O2 3
NAD 3
urea 3
Cardiol 3
DBA 3
Optimal 3
arginine 3
MAP 3
galactose 3
Adriamycin 3
vitamin D 3
oxalate 3
TNM 3
NADPH 3
MDA 3
NADPH 3
DBA 3
COS 3
MTT 3
pyrimidine 3
Phe 3
tryptophan 3
nitrogen 3
pyrimidine 3
DAMP 2
ADR 2
GSH 2
PPBP 2
NAD 2
tryptophan 2
AGE 2
anthracene 2
chromate 2
H2S 2
naphthalene 2
palmitic acid 2
SO3 2
more...