Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P05109 (S100A8)
 1,212 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
S100A8 1212
S100A9 551
S100 230
Mol 119
S100A12 104
cytokine 95
TLR4 93
Sep 75
IL-6 68
TNF 65
IL-8 48
S100A7 45
NIF 43
MRP8 42
chemokine 39
MRP14 39
calcium-binding protein 39
lipopolysaccharide 38
Smad3 36
defensin 35
IL-10 32
p38 30
CD11b 30
RAGE 29
S100A6 29
S100A4 28
LPS 28
tumor necrosis factor 27
IL-17 27
myeloperoxidase 27
TGF-beta 26
MAPK 25
collagen 25
CXCL1 25
CD14 25
S100A1 24
S100A11 24
S100B 23
CCL2 23
C-reactive protein 21
MMP9 20
Smad2 20
S100A10 19
STAT3 19
CD4 18
S100A2 17
activin 17
receptor for advanced glycation end-products 17
CD68 17
interferon 17
IL-1 16
IL-22 16
IL1B 16
IFN 16
Pseudomonas 16
lymphoid 16
granulocyte 15
plasminogen activator inhibitor-1 15
TOF 15
transforming growth factor-beta 14
p53 14
TLR2 13
MMP1 13
CXCL2 13
insulin 13
CCL20 13
high mobility group box 1 12
p65 12
histone 12
RANTES 12
inducible nitric oxide synthase 12
HLA-DR 12
S100P 12
THP 11
glycoprotein 11
albumin 11
CRP 11
gut 11
Smad7 11
MyD88 11
matrix metalloproteinase 11
SOD 10
JNK 10
SDS 10
vascular endothelial growth factor 10
MRP 10
mast cell 10
calcium binding protein 10
serum amyloid A 10
IL6 10
IL-23 10
calgranulin C 10
fibrinogen 9
ESI 9
IL-13 9
CCL3 9
macrophage colony-stimulating factor 9
dihydrofolate reductase 9
CXCL10 9
CD36 9
HMGB1 9
MMP8 9
lysozyme 8
IFN-gamma 8
MD-2 8
CD8 8
S100A3 8
hemoglobin 8
TNF-alpha 8
MHC 8
osteopontin 8
ERK 8
cystatin A 8
LL-37 8
haptoglobin 8
epidermal growth factor receptor 8
Smad1 8
MMP3 8
MMP2 7
Cytokine 7
ALK5 7
GM-CSF 7
estrogen receptor 7
p21 7
CXCL5 7
AP-1 7
ERK1 7
endoplasmic reticulum 7
S100A13 7
alkaline phosphatase 7
tumor necrosis factor alpha 7
MIP 7
type I collagen 7
activin A 7
nodal 7
interleukin-6 7
dimeric 7
LTF 7
ATP 7
fibronectin 7
hinge 7
SAA3 7
A-I 7
IL-18 7
c-Jun 7
G-CSF 7
annexin A1 7
caspase-3 7
IL-17F 7
bone morphogenetic protein 6
IL10 6
calmodulin 6
SLPI 6
proline-rich 6
cage 6
AKT 6
CD18 6
LCN2 6
NLRP3 6
polypeptide 6
lactoferrin 6
CD33 6
granulocyte colony-stimulating factor 6
cystic fibrosis antigen 6
CXCR2 6
STAT 6
IFNG 6
nitric oxide synthase 6
SOD2 6
COX-2 6
monocyte chemoattractant protein-1 6
plasminogen activator inhibitor 6
RANKL 6
CD16 6
ROS 6
CD163 6
S100A5 6
cystatin C 5
extracellular matrix metalloproteinase inducer 5
CD146 5
CXCL3 5
lactate dehydrogenase 5
renal amyloidosis 5
Smad6 5
membrane-bound 5
HSP70 5
PI3K 5
secretory protein 5
cytoplasmic protein 5
CD44 5
CXCL9 5
IL-4 5
COPD 5
Met 5
CD34 5
cytokine receptor 5
glutathione S-transferase 5
MMP-2 5
mucin 5
CCL4 5
IL-24 5
CXCR3 5
filaggrin 5
ANXA1 5
IL1RN 5
myostatin 5
CD11c 5
MMP-9 5
mTOR 5
erythroid 5
fused 5
IgE 5
neutrophil protein 4
EGR1 4
keratin 4
superoxide dismutase 4
eotaxin 4
monocyte chemotactic protein 1 4
CXCR4 4
CCL7 4
MLP 4
FAS 4
CD25 4
metalloproteinase 4
vimentin 4
OCM 4
beta-thromboglobulin 4
SOCS3 4
NGAL 4
LTA 4
MCP-1 4
CCR2 4
SPRR3 4
SPP1 4
MAC 4
IL1A 4
phosphatase 4
CX3CR1 4
EGFR 4
mitogen-activated protein 4
PC-3 4
indoleamine 2,3-dioxygenase 4
Sp1 4
c-fms 4
VEGF 4
TNFRSF1A 4
natural killer cell 4
IL-5 4
IL-2 4
neuroplastin 4
thrombospondin 4
PTGS2 4
cyclooxygenase-2 4
retinoic acid receptor 4
involucrin 4
differentially expressed protein 4
IL-16 4
ferritin 4
annexin V 4
ubiquitin 4
CD45 4
serine protease 4
CD166 4
bradykinin 3
platelet-derived growth factor 3
signal transducer and activator of transcription 3 3
cytochrome P450 3
histone deacetylase 3
BAX 3
SAA 3
PLA 3
STAT1 3
nuclear protein 3
K16 3
adhesion molecule 3
alpha-smooth muscle actin 3
mer 3
DEFB4 3
adiponectin 3
IFITM3 3
all-trans 3
MMP7 3
proto-oncogene 3
HLA 3
IL18RAP 3
interleukin 6 3
CD74 3
Tumor necrosis factor 3
serum albumin 3
leptin 3
S100A14 3
CORA 3
CSF2 3
serum protein 3
HMOX1 3
amyloid beta 3
vascular endothelium 3
matrix metalloprotease 3
SAGE 3
E-cadherin 3
neutrophil elastase 3
thymus 3
catalase 3
thioredoxin 3
Uteroglobin 3
adrenomedullin 3
TRAF2 3
epidermal growth factor 3
smooth muscle actin 3
IL-33 3
NOD 3
KRT4 3
galectin-3 3
ALOX5 3
tear lipocalin 3
A20 3
ITGB2 3
extracellular signal-regulated kinase 3
PBS 3
ATP synthase 3
more...
Disease
cancer 164
tumor 151
psoriasis 43
breast cancer 42
rheumatoid arthritis 33
carcinoma 32
atherosclerosis 28
arthritis 28
carcinogenesis 26
tumorigenesis 25
tumor growth 25
melanoma 24
tumor progression 24
metastases 22
sepsis 22
sepsis 22
asthma 20
plaque 19
dermatitis 19
diabetes 19
skin disease 18
obesity 18
squamous cell carcinoma 17
cardiovascular disease 15
chronic obstructive pulmonary disease 15
colitis 15
Alzheimer's disease 15
osteoarthritis 15
leukemia 14
atopic dermatitis 14
cystic fibrosis 14
hepatocellular carcinoma 13
colorectal cancer 13
adenocarcinoma 13
inflammatory bowel disease 13
prostate cancer 12
myocardial infarction 11
SDS 11
stroke 10
Crohn's disease 10
bladder cancer 10
periodontitis 10
type 2 diabetes 10
primary tumor 9
systemic lupus erythematosus 9
autoimmune disease 9
bacterial infection 9
Mycobacterium 8
lung cancer 8
malaria 8
colon cancer 8
skin cancer 8
infectious diseases 8
glomerulonephritis 7
gastric cancer 7
lymphoma 7
synovitis 7
acute myeloid leukemia 7
HIV 7
MIP 7
pancreatic cancer 7
dysplasia 6
keratitis 6
ischemia 6
aggressiveness 6
ovarian cancer 6
vasculitis 6
uterus 6
MCF 6
transitional cell carcinoma 6
immunopathology 5
heart failure 5
lung disease 5
Kawasaki disease 5
multiple sclerosis 5
periodontal disease 5
myelodysplastic syndrome 5
myeloproliferative disorders 5
influenza 5
acute myocardial infarction 5
COPD 5
adenoma 5
renal disease 5
hyperglycemia 5
pneumonia 5
coronary artery disease 5
myocardial ischemia 5
uveitis 5
Vulvovaginal candidiasis 5
tuberculosis 5
arthropathy 4
lung carcinoma 4
Leukemia 4
cerebral ischemia 4
gout 4
fatty liver 4
FAS 4
metastatic breast cancer 4
urolithiasis 4
diabetic nephropathy 4
ulcerative colitis 4
MAC 4
candidiasis 4
chronic myeloid leukemia 4
endometritis 4
mastitis 4
anterior uveitis 4
dyslipidemia 4
graft-versus-host disease 4
vaccinia 4
lupus 4
respiratory failure 4
Klebsiella 4
glioma 3
cirrhosis 3
ductal carcinoma 3
cervical cancer 3
cardiomyopathy 3
ovarian cysts 3
endometrial cancer 3
Systemic juvenile idiopathic arthritis 3
cerebral infarction 3
pertussis 3
lupus nephritis 3
lymphadenopathy 3
bronchiolitis 3
Infection 3
Blocking 3
pancreatitis 3
cholera 3
SARS 3
osteoporosis 3
anemia 3
hypertension 3
depression 3
cytomegalovirus 3
colibacillosis 3
sarcoidosis 3
cornea 3
gingivitis 3
vagina 3
NOD 3
hyperkeratosis 3
LCA 3
SCID 3
Melanoma 3
HGF 3
emphysema 3
DBA 3
hepatitis 2
genetic disorder 2
chronic liver disease 2
preeclampsia 2
juvenile rheumatoid arthritis 2
abdominal obesity 2
meningitis 2
psoriatic arthritis 2
Spondyloarthritis 2
liver disease 2
giant cell arteritis 2
proteinuria 2
encephalitis 2
blindness 2
Lupus 2
sickle cell disease 2
dementia 2
lupus 2
familial Mediterranean fever 2
chorioamnionitis 2
ankylosing spondylitis 2
oropharyngeal squamous cell carcinoma 2
laryngeal squamous cell carcinoma 2
Placenta 2
essential thrombocythemia 2
systemic disease 2
metabolic syndrome 2
metastatic melanoma 2
Roth 2
irritable bowel syndrome 2
HLA-B27 2
thrombocytopenia 2
food allergy 2
skin tumor 2
infectious endocarditis 2
bronchopneumonia 2
acute lymphoblastic leukemia 2
Thrombus 2
primary myelofibrosis 2
head and neck cancer 2
impotence 2
chronic lymphocytic leukemia 2
Still's disease 2
renal cancer 2
HNSCC 2
Adhesion 2
ichthyosis 2
oral cancer 2
vaginal candidiasis 2
liver fibrosis 2
MAR 2
dental caries 2
ichthyosis 2
AIDS 2
schizophrenia 2
idiopathic pulmonary fibrosis 2
urinary tract infection 2
abortion 2
acute appendicitis 2
hypercholesterolemia 2
mastocytosis 2
neutropenia 2
coronary heart disease 2
hyperlipidemia 2
mole 2
Colitis 2
vaginal infection 2
cold 2
cognitive impairment 2
interstitial pneumonia 2
rash 2
renal cell carcinoma 2
lung metastases 2
embryonal carcinoma 2
vaginitis 2
leg ulcers 2
Johne's disease 2
monocytic leukemia 2
sarcoma 2
arthrodesis 2
pyometra 2
Hepatocellular carcinoma 2
lichen planus 2
type 1 diabetes 2
thrombocytosis 2
pulmonary fibrosis 2
polycythemia vera 2
familial adenomatous polyposis 1
Spleen 1
glycogen storage disease 1
diabetic cardiomyopathy 1
tumor vasculature 1
viral hepatitis 1
intracranial aneurysm 1
virus infection 1
infestation 1
trismus 1
vitamin D deficiency 1
bipolar disorder 1
transient ischemic attack 1
PSA 1
Esophageal squamous cell carcinoma 1
cellulitis 1
major depressive disorder 1
Graves' disease 1
Chagas 1
spondyloarthropathy 1
lymphatic vessels 1
Testes 1
warts 1
cancer recurrence 1
tophi 1
CTX 1
leprosy 1
plexiform neurofibroma 1
mouth disease 1
glioblastoma multiforme 1
otitis media 1
protein deficiency 1
premature rupture of membranes 1
Evans 1
chikungunya 1
anal cancer 1
atherosclerotic cardiovascular disease 1
pruritus 1
Zinc deficiency 1
PPR 1
BLM 1
glomerulosclerosis 1
xanthomatosis 1
cervical squamous cell carcinoma 1
chronic eosinophilic leukemia 1
Mastocytosis 1
eczema 1
SLE 1
epidermodysplasia verruciformis 1
transitional cell carcinoma of the bladder 1
cholecystitis 1
bone disease 1
aspergillosis 1
gallstones 1
Fibrodysplasia ossificans progressiva 1
middle ear 1
CACA 1
epidermolysis bullosa 1
cholesteatoma 1
muscular dystrophy 1
Mycoplasma 1
fibroma 1
facet joint degeneration 1
deep vein thrombosis 1
keratosis 1
encephalomyelitis 1
Spitz nevus 1
LAP 1
gastrointestinal cancer 1
worms 1
gastrointestinal stromal tumor 1
myelofibrosis 1
aplastic anemia 1
pulmonary edema 1
liver metastases 1
fibromyalgia 1
lymphadenitis 1
degenerative disease 1
fibrosarcoma 1
filariasis 1
peritonitis 1
B-ALL 1
peritonsillar abscess 1
liver cancer 1
more...
Symptom
pain 7
dry eye 4
erythema 4
starvation 4
diarrhea 3
Gastrointestinal symptoms 1
halitosis 1
exhaustion 1
respiratory distress 1
wheezing 1
skin damage 1
back pain 1
abdominal pain 1
chest pain 1
hepatomegaly 1
discomfort 1
Fluctuation 1
hypothermia 1
Scratch 1
microbial colonization 1
scaly skin 1
discomfort 1
muscle cramps 1
fever of unknown origin 1
functional recovery 1
weakness 1
Drug
Dermatol 31
CSF 9
IFN-gamma 7
G-CSF 7
ROS 6
ROC 5
Monit 4
Gel 4
IL-2 4
Activin 3
Retinoic acid 3
MAP 3
Cardiovasc 2
Imiquimod 2
GEO 2
Glutathione 2
p75 2
MRC 2
lysine 2
Asthma 2
Fulvestrant 1
Doxycycline 1
CTX 1
Pronase 1
ADM 1
Adriamycin 1
Prednisolone 1
Tocilizumab 1
uPA 1
NADH 1
Methylprednisolone 1
Glucagon 1
Camp 1
Angiotensin II 1
PTH 1
CTC 1
IL-1ra 1
PDL 1
Rutin 1
NOV 1
IFN-beta 1
Forskolin 1
-deoxyadenosine 1
CTC 1
Taxol 1
CIA 1
CTX 1
TiO2 1
Albumin 1
Ferumoxytol 1
Allergen 1
CTX 1
ABC 1
Enzyme
mitogen-activated protein kinase 46
ERK 37
luciferase 34
peroxidase 29
trypsin 16
NADPH oxidase 12
NADPH oxidase 12
protein kinase C 10
collagenase 10
dihydrofolate reductase 9
lysozyme 8
protein kinase 8
focal adhesion kinase 7
alkaline phosphatase 7
glutathione S-transferase 7
MIP 7
reverse transcriptase 6
arginase 5
superoxide dismutase 5
lactate dehydrogenase 5
caspase-3 5
caspase-1 4
MMP-3 4
alanine aminotransferase 4
NO synthase 4
neutrophil elastase 3
alpha-amylase 3
cathepsin D 3
lipase 3
urokinase-type plasminogen activator 3
glutathione peroxidase 3
SNO 3
dihydropteroate synthase 3
elastase 3
matrix metalloproteinase 2 3
NOS 3
ATP synthase 3
aspartate aminotransferase 3
chitinase 3
catalase 3
MAP 3
P-glycoprotein 2
NQO1 2
cathepsin B 2
TMT 2
proteinase K 2
ACE 2
plasmin 2
proteasome 2
BAL 2
furin 2
proteinase-3 2
RNase 2
phospholipase A2 2
ceruloplasmin 2
indoleamine 2,3-dioxygenase 2
MMP 2
RNase 2
lysyl oxidase 2
renin 2
peroxiredoxin 2
GSK 2
cathepsin L 2
heparinase 2
calcineurin 2
TACE 2
chloramphenicol acetyltransferase 2
transglutaminase 2
AMP-activated protein kinase 1
urease 1
lipoxygenase 1
thymidine kinase 1
transaldolase 1
interstitial collagenase 1
ALA synthase 1
acid phosphatase 1
enolase 1
methylenetetrahydrofolate dehydrogenase 1
cyclohydrolase 1
thrombin 1
RNA polymerase 1
tryptase 1
Omi/HtrA2 1
AST 1
12-lipoxygenase 1
acyl-CoA dehydrogenase 1
SPT 1
creatine kinase 1
tissue plasminogen activator 1
retinal dehydrogenase 1
amylomaltase 1
kynureninase 1
IKK 1
PGM 1
ATPase 1
AMPK 1
S1 nuclease 1
histone demethylase 1
endonuclease 1
topoisomerase 1
phosphodiesterase 1
hyaluronidase 1
CD10 1
glutamine synthetase 1
tryptophan hydroxylase 1
DNA polymerase 1
DNase 1
ribonuclease 1
topoisomerase 1
SST 1
PHD 1
caspase-4 1
hexokinase 1
factor C 1
nicotinamide phosphoribosyltransferase 1
ribonuclease 1
KLK7 1
phospholipase C 1
phosphoserine phosphatase 1
neuropathy target esterase 1
urease 1
ubiquitin-protein ligase 1
glucokinase 1
MDR 1
glutathione reductase 1
tyrosinase 1
polo-like kinase 1 1
FPS 1
neutrophil collagenase 1
cathepsin G 1
matrix metalloproteinase 9 1
PARP 1
phosphatidylinositol 3-kinase 1
adenosine deaminase 1
S-adenosyl-L-homocysteine hydrolase 1
chondroitinase 1
chymotrypsin 1
LTA4 hydrolase 1
MDP 1
MEK 1
AMPK 1
chondroitinase 1
kallikrein 1
methylenetetrahydrofolate dehydrogenase 1
caspase-4 1
LPL 1
cathepsin K 1
prostaglandin synthetase 1
AGT 1
adenosine deaminase 1
Compound
calcium 195
DNA 90
Dec 88
TNF 65
Clin 45
zinc 43
oxygen 38
sodium 23
His 19
water 18
sulfate 18
methionine 16
TOF 15
manganese 15
acetate 14
glucose 12
retinoic acid 12
THP 11
THP 11
nitric oxide 11
SDS 10
cysteine 10
copper 10
alanine 10
PMA 9
PMA 8
Asp 7
ATP 7
ClO 6
serine 6
creatinine 6
iron 6
hydrogen 6
silver 5
phosphate 5
cAMP 5
ethanol 5
PGE 4
leucine 4
DBA 4
threonine 4
lysine 4
DBA 3
TNM 3
NADPH 3
MTT 3
oxalate 3
MAP 3
galactose 3
MDA 3
Optimal 3
H2O2 3
vitamin D 3
DBA 3
Adriamycin 3
Cardiol 3
PGE2 3
NAD 3
urea 3
pyrimidine 3
NADPH 3
tryptophan 3
Phe 3
nitrogen 3
arginine 3
COS 3
pyrimidine 3
AGE 2
Heparan sulfate 2
DAMP 2
tryptophan 2
anthracene 2
tryptophan 2
SO3 2
Keratin 2
CoA 2
DAMP 2
palmitic acid 2
naphthalene 2
H2S 2
PPBP 2
NAD 2
chromate 2
diacetate 2
tyrosine 2
BAL 2
tryptophan 2
ADR 2
bromide 2
STZ 2
NTA 2
PAS 2
Lip 2
DMSO 2
Gly 2
FMLP 2
GSH 2
GSH 2
chloroform 2
retinol 2
potassium 2
Tumor Necrosis Factor 2
palmitic acid 2
TACE 2
Trenimon 1
Diclofenac 1
IPA 1
A 3 1
Sulforaphane 1
Narciclasine 1
NH2 1
TPA 1
MDR 1
ANS 1
Tris 1
4-chlorophenyl 1
Pyrimethamine 1
5,5-dimethyl-1,3-cyclohexanedione 1
Tazarotene 1
boron 1
DAG 1
trifluoroacetic acid 1
SSH 1
Metformin 1
Tamoxifen 1
P-D 1
Brefeldin A 1
4-chlorophenyl 1
Dibutyryl cyclic AMP 1
TPA 1
Cbl 1
THE 1
DEAE 1
titanium 1
5-Aza-2'-deoxycytidine 1
DEK 1
Oleic acid 1
TAR 1
Cordycepin 1
stearic acid 1
Metformin 1
TTNPB 1
Phorbol 12-myristate 13-acetate 1
Oil Red O 1
Estrogen 1
acetonitrile 1
Cordycepin 1
MES 1
DBP 1
IPA 1
phosphorus 1
XTT 1
Oil Red O 1
TEM 1
vinyl 1
BAP 1
PGFM 1
Prostaglandin 1
Evans Blue 1
stearic acid 1
phenazine 1
formaldehyde 1
NADH 1
Carrageenan 1
EDTA 1
quinoline 1
salt 1
Prostaglandin 1
DBP 1
LIN 1
Daunorubicin 1
IPA 1
UDP 1
trifluoroacetic acid 1
TCA 1
Resveratrol 1
stearic acid 1
trifluoroacetic acid 1
hydroxide 1
Pac 1
Brefeldin A 1
Angiotensin II 1
IPA 1
Estrogen 1
Ang II 1
Cordycepin 1
trifluoroacetic acid 1
Dibutyryl cyclic AMP 1
Vitamin D 1
PEG 1
CTX 1
IDC 1
TIF 1
UTP 1
Cysteine 1
Cycloheximide 1
Lead 1
Lactate 1
Doxycycline 1
trifluoroacetic acid 1
DTE 1
Flucloxacillin 1
SCC 1
PPD 1
Fibrinogen 1
keratan sulfate 1
Tamoxifen 1
Plasmin 1
Phorbol 1
Prednisolone 1
Rutin 1
Mg2+ 1
BCG 1
Cyclosporine 1
Forskolin 1
4-hydroxybenzoic acid 1
glutamic acid 1
GSSG 1
2-hydroxy-3-methoxybenzaldehyde 1
PVA 1
Triton X-100 1
Isoproterenol 1
LPC 1
pyrrolidine 1
ANS 1
Poly(I:C) 1
CHIP 1
L-DOPA 1
Flavonoid 1
PEG 1
3,4-dihydroxybenzaldehyde 1
COX 1
Insulin 1
NMDA 1
CTP 1
thioglycollate 1
Methylprednisolone 1
TTA 1
ammonia 1
BLM 1
DAD 1
EDTA 1
fluorine 1
selenium 1
myricetin 1
nicotinamide 1
ABL 1
Thymine 1
DTPA 1
DPP 1
PPD 1
MES 1
methanol 1
TAA 1
ICI 1
aluminum 1
quinoline 1
3,4-dihydroxybenzaldehyde 1
isopropanol 1
Serine 1
5-HT 1
pyrrolidine 1
Tris 1
MEK 1
6-12 1
Brilliant Blue 1
ASC 1
Glucagon 1
ADP-ribose 1
Coenzyme A 1
phenol 1
Fibrinopeptide A 1
C2H2 1
Arachidonic acid 1
DHA 1
Leukotriene B4 1
Hemoglobin 1