Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P04637 (p53)
 77,613 document(s) hit in 31,850,051 MEDLINE articles (0.05 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
p53 1.000
p21 0.042
mutant p53 0.035
MDM2 0.031
Mdm2 0.016
p73 0.014
p53 target 0.013
p16 0.010
Bcl-2 0.010
tumour suppressor 0.009
WAF1 0.007
ATM 0.007
mdm2 0.006
bcl-2 0.006
p63 0.005
caspase-3 0.005
PUMA 0.005
Li-Fraumeni syndrome 0.005
Ki-67 0.005
CIP1 0.005
bax 0.004
pRb 0.004
MDM2 protein 0.004
INK4a 0.004
CDKN2A 0.003
PTEN 0.003
K-ras 0.003
ARF 0.003
MDMX 0.003
HDM2 0.003
Hdm2 0.003
p27 0.003
PIK3CA 0.003
KRAS 0.003
cyclin D1 0.003
RB1 0.003
p16INK4a 0.002
Chk2 0.002
E6 protein 0.002
CDKN1A 0.002
p21 protein 0.002
caspase-9 0.002
BAX 0.002
BRCA1 0.002
proliferating cell nuclear antigen 0.002
Chk1 0.002
MDM4 0.002
c-myc 0.002
cyclin-dependent kinase inhibitor 0.002
PARP 0.002
H2AX 0.002
cyclin E 0.002
E2F1 0.002
tumor suppressor protein 0.002
p14 0.001
ras 0.001
GADD45 0.001
cyclin 0.001
MIB 0.001
c-Myc 0.001
erbB-2 0.001
cyclin B1 0.001
SMAD4 0.001
ataxia telangiectasia mutated 0.001
CDK4 0.001
EGFR 0.001
MYC 0.001
BRCA2 0.001
ASPP2 0.001
p19ARF 0.001
p19 0.001
CIP1/WAF1 0.001
caspase-8 0.001
ARID1A 0.001
APC 0.001
p300 0.001
CHK2 0.001
survivin 0.001
cyclin-dependent kinase 0.001
Mol 0.001
more...
Disease
tumor 0.013
cancer 0.011
tumorigenesis 0.005
carcinogenesis 0.004
Li-Fraumeni syndrome 0.004
ATM 0.004
retinoblastoma 0.003
carcinoma 0.003
breast cancer 0.002
tumor progression 0.001
ARF 0.001
adenocarcinoma 0.001
squamous cell carcinoma 0.001
lung cancer 0.001
colon cancer 0.001
colorectal cancer 0.001
MCF 0.001
tumor growth 0.001
hepatocellular carcinoma 0.001
APC 0.001
glioblastoma 0.001
ovarian cancer 0.001
ATRX 0.001
glioma 0.001
non-small cell lung cancer 0.001
chronic lymphocytic leukemia 0.001
cervical cancer 0.000
leukemia 0.000
osteosarcoma 0.000
metastases 0.000
chronic lymphocytic leukemia 0.000
B-cell lymphoma 0.000
skin cancer 0.000
bladder cancer 0.000
dysplasia 0.000
melanoma 0.000
MDM 0.000
prostate cancer 0.000
lymphoma 0.000
gastric cancer 0.000
epithelial ovarian cancer 0.000
human papilloma virus 0.000
human papilloma virus 0.000
neoplastic transformation 0.000
CM1 0.000
pancreatic cancer 0.000
endometrial cancer 0.000
lung carcinoma 0.000
acute myeloid leukemia 0.000
adenoma 0.000
aggressiveness 0.000
liver cancer 0.000
neuroblastoma 0.000
glioblastoma multiforme 0.000
primary tumor 0.000
sarcoma 0.000
myelodysplastic syndrome 0.000
liver cancer 0.000
astrocytoma 0.000
tumor initiation 0.000
WT1 0.000
Hepatocellular carcinoma 0.000
medulloblastoma 0.000
brain tumor 0.000
Barrett's esophagus 0.000
anaplastic astrocytoma 0.000
oral cancer 0.000
familial cancer 0.000
papilloma 0.000
xeroderma pigmentosum 0.000
HNSCC 0.000
carcinoma in situ 0.000
esophageal cancer 0.000
ductal carcinoma in situ 0.000
ductal carcinoma 0.000
Epstein 0.000
adrenocortical carcinoma 0.000
refractory CLL 0.000
esophageal cancer 0.000
mantle cell lymphoma 0.000
more...
Symptom
starvation 0.000
skin damage 0.000
hyperoxia 0.000
collapse 0.000
exhaustion 0.000
ataxia 0.000
prickling sensation 0.000
masculinization 0.000
Mucosal hyperplasia 0.000
High weight 0.000
Skin thickening 0.000
cardiovascular problem 0.000
splenomegaly 0.000
RNA marker 0.000
erythema 0.000
seizures 0.000
Scratch 0.000
abdominal pain 0.000
pachyonychia 0.000
cachexia 0.000
functional recovery 0.000
diarrhea 0.000
Flu-like symptoms 0.000
anal pain 0.000
abdominal fullness 0.000
Grimace 0.000
Sister Mary Joseph's nodule 0.000
nausea 0.000
acute stress 0.000
nipple discharge 0.000
thinning 0.000
nipple discharge 0.000
vomiting 0.000
HSA 0.000
disturbed balance 0.000
DNA marker 0.000
pain 0.000
epigastric pain 0.000
fatigue 0.000
male subfertility 0.000
memory loss 0.000
hypothermia 0.000
female puberty 0.000
decreased appetite 0.000
left upper quadrant pain 0.000
respiratory distress 0.000
headache 0.000
Physical findings 0.000
dysuria 0.000
hepatomegaly 0.000
forgetfulness 0.000
scaly skin 0.000
cerebellar ataxia 0.000
peri-menopausal 0.000
Neurologic symptoms 0.000
abdominal discomfort 0.000
impaired motor coordination 0.000
Noise-induced hearing loss 0.000
tingling 0.000
weakness 0.000
labored breathing 0.000
tenesmus 0.000
cough 0.000
abnormal breathing 0.000
paraparesis 0.000
sore throat 0.000
Anoxia 0.000
back pain 0.000
Fluctuation 0.000
hepatosplenomegaly 0.000
urethral discharge 0.000
right upper quadrant pain 0.000
chest pain 0.000
dyspnea 0.000
No adverse effect 0.000
bone pain 0.000
intention tremor 0.000
bradykinesia 0.000
Tenderness 0.000
low back pain 0.000
more...
Drug
PFT 0.001
ROS 0.000
MDM 0.000
Paraffin 0.000
lysine 0.000
Advexin 0.000
Mutagen 0.000
MDS 0.000
Taxol 0.000
Etoposide 0.000
Arsenic trioxide 0.000
AGG 0.000
CDX 0.000
BLM 0.000
GEO 0.000
Bortezomib 0.000
Adriamycin 0.000
G418 0.000
CDX 0.000
caffeine 0.000
Efaproxiral sodium 0.000
ETS 0.000
Teroxirone 0.000
Oxaliplatin 0.000
Flavopiridol 0.000
CPT-11 0.000
MAP 0.000
Parkin 0.000
Parkin 0.000
NVP 0.000
Vorinostat 0.000
Ibutamoren mesylate 0.000
Talactoferrin alfa 0.000
Pyrroloquinoline Quinone 0.000
Senega 0.000
Sophora root 0.000
PTC 0.000
Irinotecan 0.000
Valcyte 0.000
TTC 0.000
MRC 0.000
7-Hydroxystaurosporine 0.000
ADR 0.000
Canertinib dihydrochloride 0.000
Dermatol 0.000
VCR 0.000
Irofulven 0.000
Zedoary 0.000
CED 0.000
ABC 0.000
Canfosfamide hydrochloride 0.000
Dried yeast 0.000
Epigallocatechin 0.000
TAT 0.000
Fludarabine 0.000
2-Methoxyestradiol 0.000
Docetaxel 0.000
Haemanthamine 0.000
Motexafin lutetium 0.000
Apomorphine hydrochloride 0.000
Romidepsin 0.000
Olomoucine 0.000
Amifostine 0.000
Gefitinib 0.000
Icatibant acetate 0.000
Lexatumumab 0.000
Zebularine 0.000
Lenalidomide 0.000
Imatinib 0.000
uPA 0.000
Pemetrexed 0.000
p75 0.000
Propidium 0.000
TAC 0.000
APD-356 0.000
Apaziquone 0.000
Alimta 0.000
Trabectedin 0.000
CTT 0.000
Pazopanib hydrochloride 0.000
more...
Enzyme
caspase-3 0.004
ERK 0.002
PARP 0.002
caspase-9 0.002
cdc2 0.001
mitogen-activated protein kinase 0.001
caspase-8 0.001
STK11 0.001
proteasome 0.001
APC 0.001
protein kinase 0.001
luciferase 0.000
topoisomerase 0.000
caspase-2 0.000
topoisomerase 0.000
focal adhesion kinase 0.000
caspase-2 0.000
AMP-activated protein kinase 0.000
MEK 0.000
AMPK 0.000
caspase-7 0.000
caspase-7 0.000
histone acetyltransferase 0.000
superoxide dismutase 0.000
catalase 0.000
AMPK 0.000
glutathione S-transferase 0.000
polo-like kinase 1 0.000
phosphatidylinositol 3-kinase 0.000
TdT 0.000
CGT 0.000
thymidylate synthase 0.000
CEP 0.000
beta-galactosidase 0.000
ubiquitin-protein ligase 0.000
P-glycoprotein 0.000
GSK 0.000
NQO1 0.000
RNA polymerase 0.000
ribonucleotide reductase 0.000
ribonucleotide reductase 0.000
caspase-6 0.000
caspase-6 0.000
CEP 0.000
CD10 0.000
phosphoinositide 3-kinase 0.000
DNA methyltransferase 0.000
cathepsin D 0.000
thymidine kinase 0.000
protein kinase C 0.000
calcineurin 0.000
caspase-1 0.000
protein phosphatase 2A 0.000
IKK 0.000
glutathione peroxidase 0.000
reverse transcriptase 0.000
DNA polymerase 0.000
lactate dehydrogenase 0.000
AGT 0.000
TGT 0.000
endonuclease 0.000
MAP 0.000
phosphatidylinositol-4,5-bisphosphate 3-kinase 0.000
ADE2 0.000
histone demethylase 0.000
isocitrate dehydrogenase 0.000
bovine leukemia virus protease 0.000
isocitrate dehydrogenase 0.000
PDK1 0.000
thymidine phosphorylase 0.000
caspase-10 0.000
caspase-10 0.000
DNA ligase 0.000
DNA ligase 0.000
BAT 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
ornithine decarboxylase 0.000
caspase-4 0.000
MDR 0.000
MMP 0.000
more...
Compound
DNA 0.008
NOXA 0.001
MTT 0.001
oxygen 0.000
MDA 0.000
dUTP 0.000
DDP 0.000
DCC 0.000
serine 0.000
ADP-ribose 0.000
urea 0.000
Dec 0.000
arginine 0.000
TNM 0.000
MEK 0.000
Adriamycin 0.000
N-acetylcysteine 0.000
Resveratrol 0.000
boron 0.000
ADR 0.000
aflatoxin B1 0.000
TNF 0.000
pyrene 0.000
lysine 0.000
threonine 0.000
Curcumin 0.000
SCC 0.000
GSH 0.000
GSH 0.000
5-FU 0.000
NAD 0.000
pyrimidine 0.000
pyrimidine 0.000
cysteine 0.000
CAT 0.000
CAT 0.000
NAD 0.000
tyrosine 0.000
CAT 0.000
XPA 0.000
XPA 0.000
Ubiquitin 0.000
retinoic acid 0.000
proline 0.000
VP-16 0.000
Oridonin 0.000
Clin 0.000
8-OHdG 0.000
nitric oxide 0.000
anthracene 0.000
methionine 0.000
bromide 0.000
Histone 0.000
Triptolide 0.000
ATP 0.000
BLM 0.000
Serine 0.000
iodine 0.000
ATF 0.000
TGT 0.000
zinc 0.000
PALA 0.000
nicotinamide 0.000
H2O2 0.000
Vimentin 0.000
5-Aza-2'-deoxycytidine 0.000
Temozolomide 0.000
Apigenin 0.000
glucose 0.000
CCC 0.000
Thymoquinone 0.000
acridine 0.000
Sulforaphane 0.000
Paclitaxel 0.000
Nitidine 0.000
methyl methanesulfonate 0.000
Bathocuproine 0.000
caffeine 0.000
BCR 0.000
Hoechst 33342 0.000
more...