Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UNIPROT:P04637 (p53)
77,613 document(s) hit in 31,850,051 MEDLINE articles (0.05 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein p53 77613 p21 8303 Mol 6846 Bcl-2 5050 Sep 4868 caspase-3 4298 MDM2 3176 mutant p53 3017 p16 2496 Ki-67 2138 tumour suppressor 2001 bcl-2 1895 ATM 1744 cyclin D1 1640 PTEN 1523 proliferating cell nuclear antigen 1422 p73 1399 Mdm2 1383 cytochrome c 1313 p27 1309 AKT 1250 ubiquitin 1247 caspase-9 1246 ras 1246 WAF1 1240 BRCA1 1220 c-myc 1195 KRAS 1194 PARP 1181 MAPK 1180 p63 1176 histone 1172 PI3K 1170 p38 1161 EGFR 1151 proteasome 1138 p53 target 1113 cyclin 1103 mTOR 1099 Fas 980 estrogen receptor 954 epidermal growth factor receptor 913 c-Myc 897 pRb 895 INK4a 891 bax 882 K-ras 845 caspase-8 844 CDKN2A 830 cytokine 829 ROS 825 ERK 805 BRAF 802 JNK 800 ARF 794 CIP1 790 APC 790 PIK3CA 787 HER2 784 catenin 773 cyclin E 767 BAX 752 erbB-2 745 H2AX 711 osteosarcoma 694 MYC 691 TNF 681 p16INK4a 680 Chk1 673 E-cadherin 670 BRCA2 667 cyclin-dependent kinase 642 PUMA 624 CDK4 616 vimentin 609 tumor necrosis factor 608 survivin 604 vascular endothelial growth factor 599 RB1 597 ATP 597 more...

Disease cancer 30066 tumor 26657 carcinoma 5540 breast cancer 5022 tumorigenesis 4795 carcinogenesis 4750 adenocarcinoma 2562 lung cancer 2393 hepatocellular carcinoma 2197 tumor progression 2141 ATM 2085 tumor growth 2079 squamous cell carcinoma 2041 colorectal cancer 2002 metastases 1812 leukemia 1800 retinoblastoma 1609 colon cancer 1510 MCF 1454 melanoma 1369 lymphoma 1364 prostate cancer 1251 ovarian cancer 1223 glioma 1175 glioblastoma 1015 dysplasia 975 non-small cell lung cancer 958 gastric cancer 957 cervical cancer 924 acute myeloid leukemia 832 APC 803 ARF 795 chronic lymphocytic leukemia 758 osteosarcoma 755 neuroblastoma 708 B-cell lymphoma 707 bladder cancer 697 lung carcinoma 685 pancreatic cancer 660 adenoma 644 sarcoma 623 skin cancer 610 primary tumor 584 Li-Fraumeni syndrome 583 chronic lymphocytic leukemia 578 epithelial ovarian cancer 535 liver cancer 528 multiple myeloma 520 Epstein 490 endometrial cancer 481 aggressiveness 477 myelodysplastic syndrome 469 GSH 454 diabetes 443 Alzheimer's disease 420 ischemia 412 glioblastoma multiforme 401 liver cancer 396 hepatitis B 389 brain tumor 379 Leukemia 365 acute lymphoblastic leukemia 353 Hodgkin's disease 351 renal cell carcinoma 347 neoplastic transformation 343 virus infection 318 WT1 317 HIV 308 esophageal cancer 302 astrocytoma 302 chronic myeloid leukemia 287 esophageal cancer 285 Hepatocellular carcinoma 277 atherosclerosis 260 Parkinson's disease 256 anemia 255 oral cancer 252 human papilloma virus 251 head and neck cancer 251 Barrett's esophagus 251 more...

Symptom starvation 255 collapse 124 pain 99 seizures 95 diarrhea 63 ataxia 62 exhaustion 62 hyperoxia 56 abdominal pain 51 fatigue 41 erythema 40 headache 38 splenomegaly 38 vomiting 36 nausea 33 skin damage 31 functional recovery 31 weakness 26 hypothermia 23 respiratory distress 23 masculinization 22 thinning 22 cachexia 20 cough 20 anesthesia 18 dyspnea 18 chest pain 14 acute stress 14 back pain 13 hepatomegaly 11 discomfort 11 acidity 11 memory loss 10 discomfort 10 epigastric pain 10 HSA 10 low back pain 9 anorexia 9 overweight 8 cerebellar ataxia 8 hepatosplenomegaly 7 dysuria 7 ENT 6 nausea and vomiting 6 Ill 6 paraparesis 6 sore throat 6 bone pain 5 Scratch 5 hemoptysis 5 abdominal discomfort 5 dizziness 5 decreased appetite 5 DNA marker 5 constipation 5 hypotonia 5 vertigo 4 numbness 4 abdominal fullness 4 hoarseness 4 bradykinesia 4 nipple discharge 4 angina 4 nipple discharge 4 arthralgia 4 paresis 4 tremor 4 paresthesia 4 tingling 4 pelvic pain 4 hypercapnia 3 blurred vision 3 facial pain 3 chills 3 flank pain 3 neck pain 3 anal pain 3 exertional dyspnea 3 flushing 3 syncope 3 more...

Drug ROS 825 lysine 617 Dermatol 450 caffeine 195 Paraffin 156 PFT 141 Mutagen 135 MAP 134 MDM 111 Adriamycin 99 Taxol 95 Monit 95 ascorbate 94 IL-2 92 MDS 81 NADH 80 ABC 76 IFN-gamma 76 vitamin E 72 Cardiovasc 71 CSF 67 G418 63 Gel 63 GEO 59 ETS 58 Arsenic trioxide 56 BLM 56 Bortezomib 56 Etoposide 56 MRC 53 DNase I 49 CAM 46 CPT-11 46 Parkin 45 Parkin 45 AGG 43 p75 42 Asn 41 PTC 40 ADR 40 TTC 39 TAT 38 Glutathione 37 Imatinib 34 VCR 34 ZnO 33 Oxaliplatin 33 ADM 32 uPA 31 Docetaxel 31 NVP 31 Retinoic acid 30 CTX 30 Heme 27 ROC 27 Irinotecan 26 TAC 26 -deoxyadenosine 25 Gefitinib 24 CDX 24 Angiotensin II 24 CDX 24 Rituximab 23 Fluorescein 23 EE2 23 Ethanol 22 Sorafenib 22 Indomethacin 22 IFN-beta 21 ENT 21 Meth 21 Simvastatin 20 Nitric Oxide 20 CED 19 G-CSF 19 Gleevec 19 Leaf 18 CCL 18 Vorinostat 18 Vitamin E 17 more...

Enzyme ERK 3808 caspase-3 3259 mitogen-activated protein kinase 2993 protein kinase 1789 PARP 1385 proteasome 1145 cdc2 969 caspase-9 955 luciferase 820 APC 807 focal adhesion kinase 805 superoxide dismutase 674 catalase 653 caspase-8 631 MEK 502 AMP-activated protein kinase 432 topoisomerase 400 RNA polymerase 370 topoisomerase 368 glutathione S-transferase 365 protein kinase C 356 AMPK 271 AMPK 267 reverse transcriptase 262 beta-galactosidase 260 phosphatidylinositol 3-kinase 246 lactate dehydrogenase 246 P-glycoprotein 240 peroxidase 221 ATPase 220 glutathione peroxidase 220 calcineurin 208 DNA polymerase 191 CD10 182 endonuclease 181 GSK 168 NQO1 159 STK11 151 alanine aminotransferase 147 histone acetyltransferase 145 thymidine kinase 140 phosphoinositide 3-kinase 140 thymidylate synthase 138 aspartate aminotransferase 130 alkaline phosphatase 129 DNA methyltransferase 126 caspase-1 123 caspase-2 110 MAP 107 IKK 105 ACS 105 caspase-2 105 RNase 105 cathepsin D 105 ribonucleotide reductase 104 RNase 101 TdT 101 ribonucleotide reductase 100 caspase-7 97 caspase-7 94 collagenase 93 polo-like kinase 1 92 NADPH oxidase 91 NADPH oxidase 85 protein phosphatase 2A 85 urokinase-type plasminogen activator 82 glyceraldehyde-3-phosphate dehydrogenase 79 ornithine decarboxylase 78 glutathione reductase 75 prostate-specific antigen 73 NO synthase 73 complex I 68 isocitrate dehydrogenase 67 chloramphenicol acetyltransferase 67 dihydrofolate reductase 67 gamma-glutamyl transpeptidase 64 demethylase 64 MDR 64 isocitrate dehydrogenase 63 MMP 62 more...

Compound DNA 22910 Dec 5396 oxygen 3396 Clin 2237 MTT 1194 serine 1065 arginine 998 urea 959 glucose 799 MDA 786 lysine 760 TNF 681 calcium 671 water 649 tyrosine 646 ATP 597 cysteine 583 nitric oxide 551 threonine 533 hydrogen 515 sodium 480 GSH 479 GSH 479 zinc 464 dUTP 421 DDP 417 methionine 416 boron 390 pyrene 375 phosphate 368 NAD 364 iodine 359 bromide 352 proline 351 MEK 351 alanine 341 acetate 320 N-acetylcysteine 315 pyrimidine 312 pyrimidine 309 retinoic acid 307 iron 301 ADP-ribose 297 NAD 295 TNM 281 Adriamycin 279 His 264 H2O2 259 nitrogen 253 ADP 233 leucine 224 ADR 224 ethanol 217 ADP 217 ADP 217 copper 207 DCC 202 Curcumin 202 CAT 199 CAT 198 CAT 198 cAMP 196 5-FU 196 Resveratrol 195 caffeine 195 sulfate 192 nicotinamide 190 aflatoxin B1 190 anthracene 175 Asp 173 Pac 168 NH2 161 selenium 156 glutamate 152 formaldehyde 152 NOXA 151 silver 141 cadmium 139 SCC 138 salt 138 more...

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