Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P04637 (
p53
)
77,613
document(s) hit in 31,850,051 MEDLINE articles (0.06 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
p53
77613
p21
8303
Mol
6846
Bcl-2
5050
Sep
4868
caspase-3
4298
MDM2
3176
mutant p53
3017
p16
2496
Ki-67
2138
tumour suppressor
2001
bcl-2
1895
ATM
1744
cyclin D1
1640
PTEN
1523
proliferating cell nuclear antigen
1422
p73
1399
Mdm2
1383
cytochrome c
1313
p27
1309
more...
Disease
cancer
30066
tumor
26657
carcinoma
5540
breast cancer
5022
tumorigenesis
4795
carcinogenesis
4750
adenocarcinoma
2562
lung cancer
2393
hepatocellular carcinoma
2197
tumor progression
2141
ATM
2085
tumor growth
2079
squamous cell carcinoma
2041
colorectal cancer
2002
metastases
1812
leukemia
1800
retinoblastoma
1609
colon cancer
1510
MCF
1454
melanoma
1369
more...
Symptom
starvation
255
collapse
124
pain
99
seizures
95
diarrhea
63
ataxia
62
exhaustion
62
hyperoxia
56
abdominal pain
51
fatigue
41
erythema
40
splenomegaly
38
headache
38
vomiting
36
nausea
33
functional recovery
31
skin damage
31
weakness
26
hypothermia
23
respiratory distress
23
more...
Drug
ROS
825
lysine
617
Dermatol
450
caffeine
195
Paraffin
156
PFT
141
Mutagen
135
MAP
134
MDM
111
Adriamycin
99
Taxol
95
Monit
95
ascorbate
94
IL-2
92
MDS
81
NADH
80
IFN-gamma
76
ABC
76
vitamin E
72
Cardiovasc
71
more...
Enzyme
ERK
3808
caspase-3
3259
mitogen-activated protein kinase
2993
protein kinase
1789
PARP
1385
proteasome
1145
cdc2
969
caspase-9
955
luciferase
820
APC
807
focal adhesion kinase
805
superoxide dismutase
674
catalase
653
caspase-8
631
MEK
502
AMP-activated protein kinase
432
topoisomerase
400
RNA polymerase
370
topoisomerase
368
glutathione S-transferase
365
more...
Compound
DNA
22910
Dec
5396
oxygen
3396
Clin
2237
MTT
1194
serine
1065
arginine
998
urea
959
glucose
799
MDA
786
lysine
760
TNF
681
calcium
671
water
649
tyrosine
646
ATP
597
cysteine
583
nitric oxide
551
threonine
533
hydrogen
515
more...