Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P04626 (erbB-2)
5,251 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
erbB-2 12.6
SNX1A 12.6
tumor necrosis factor (ligand) superfamily, member 12 12.6
c-erbB-3 12.2
erbB-3 11.6
Sp2 transcription factor 11.6
Opioid binding protein/cell adhesion molecule-like 11.6
apoptosis repressor with CARD domain 11.0
p185 10.9
mutant p53 tumor suppressor 10.8
CBE1 10.6
ERBB3 protein 10.6
amplified in osteosarcoma 10.6
herstatin 10.6
Herstatin 10.5
c-ros-1 10.2
RING4 10.2
MUC11 10.2
CAB1 10.0
NAPG 10.0
putative transmembrane receptor 10.0
EGF receptor 9.9
NRG-4 9.8
neu 9.6
Ski oncoprotein 9.6
Eps15R 9.6
RABEP1 9.6
COLM 9.6
chemokine BRAK 9.6
TBC1D9 9.6
STARD10 9.4
VPS37B 9.4
VPS37C 9.4
NB3 9.4
MAGE2 9.2
Telethonin 9.1
rlf 9.1
Vascular endothelial growth factor D 9.1
GPR30 protein 9.0
HRG4 9.0
p55c-fgr 9.0
focal adhesion kinase 1 9.0
NRG4 9.0
HER4 8.9
Cyclin G-associated kinase 8.9
AKT2 protein 8.9
clathrin-associated protein 8.9
Br3 8.8
Calpain-2 8.8
phospholipase C-gamma 1 8.7
ErbB-3 8.7
NR6 8.7
betacellulin 8.7
B3-1 8.7
MED7 8.7
POB1 8.7
HRG 8.6
transforming growth factor-alpha 8.6
hepatocellular carcinoma related protein 1 8.6
HSTF1 8.6
CD349 8.6
SNX4 8.6
COPS3 8.6
Transforming growth factor-alpha 8.6
TOP2A protein 8.6
transforming growth factor alpha 8.5
MXI 8.5
thyroid hormone receptor alpha 1 8.5
CITED4 8.5
PINCH2 8.5
UBTF 8.5
GNN 8.5
eps15 8.4
neuregulin 8.4
STK1 8.3
tumor-related protein 8.3
lipophilin B 8.3
epidermal growth factor 8.3
HLC-1 8.2
Transforming growth factor alpha 8.2
more...
Disease
Basal cell carcinoma with sebaceous differentiation 12.6
Malignant insulinoma 9.6
Laryngeal papilloma 9.6
PanIN-1A 9.4
Psoriatic plaque 9.4
Paget's disease of the nipple 9.3
comedo carcinoma 9.2
stage IIB cervical cancer 9.1
MDD2 9.1
Secretory carcinoma of the breast 9.1
Small cell osteosarcoma 8.6
comedo 8.5
Gastric dysplasia 8.4
PanIN-1B 8.3
Salivary duct carcinoma 8.2
stage II NSCLC 8.0
PanIN-1 7.8
uterine carcinosarcoma 7.8
PanIN-3 7.7
stage IB cervical cancer 7.7
ductal carcinoma in situ 7.6
DA4 7.6
benign proliferative breast disease 7.6
cutaneous leiomyoma 7.5
infiltrating ductal carcinoma 7.5
Extramammary Paget's disease 7.4
stage III breast cancer 7.4
Endometrioid carcinoma 7.4
Liver mass 7.3
ductal carcinoma 7.3
Pleomorphic carcinoma 7.2
LCIS 7.2
erythroblastosis 7.1
ovarian tumors of low malignant potential 7.1
VIN III 7.1
PanIN-2 7.0
metaplastic carcinoma 7.0
Peritoneal metastases 7.0
metastatic endometrial cancer 6.9
stage D prostate cancer 6.9
bilateral cancer 6.9
benign ovarian cyst 6.9
stage II breast cancer 6.8
small cell carcinoma of the cervix 6.8
Hailey-Hailey disease 6.8
apocrine metaplasia 6.7
fallopian tube cancer 6.7
pediatric medulloblastoma 6.7
lobular carcinoma in situ 6.7
recurrent endometrial cancer 6.6
Precancerous lesions 6.6
bladder neoplasm 6.6
Medullary carcinoma 6.5
Ductal carcinoma 6.5
recurrent breast cancer 6.5
stage I NSCLC 6.5
Polycystic liver disease 6.5
Epithelial hyperplasia 6.4
Paget's disease of the vulva 6.4
mucinous carcinoma 6.4
breast fibroadenoma 6.2
papillary serous carcinoma 6.2
stage IIIA NSCLC 6.2
Microcystic adnexal carcinoma 6.2
GFD 6.2
Breast carcinoma 6.2
fibrocystic disease 6.2
carcinoma of the breast 6.1
extensive stage SCLC 6.0
mammary tumor 6.0
GIN 6.0
metastatic breast cancer 5.9
transitional cell carcinoma of the bladder 5.9
Meningeal carcinomatosis 5.9
Psammoma 5.9
Ullrich 5.9
in situ breast cancer 5.9
breast cancer 5.8
endocrine neoplasm 5.8
Endometrium 5.7
more...
Symptom
female puberty 5.6
peri-menopausal 5.1
nipple discharge 4.5
rigors 4.5
nipple discharge 4.5
No adverse effect 4.2
chills 2.8
HSA 2.0
dry eye 1.2
asthenia 1.2
hoarseness 1.0
epigastric pain 0.8
syncope 0.4
Ill 0.1
cachexia 0.1
hepatomegaly 0.1
hemoptysis -0.0
erythema -0.1
starvation -0.5
chest pain -0.5
nausea and vomiting -0.7
nausea -1.0
cough -1.0
functional recovery -1.1
acidity -1.3
abdominal pain -1.4
headache -1.6
diarrhea -1.7
overweight -2.1
dyspnea -2.2
collapse -2.2
vomiting -2.4
pain -2.6
weakness -2.6
seizures -2.7
fatigue -3.1
anesthesia -3.2
Drug
Gris-PEG 9.4
CEA-Scan 9.2
Herceptin 8.7
Tykerb 7.8
Radicicol 7.5
Pertuzumab 7.1
Paraffin 6.8
Ontak 6.7
Ontak 6.7
Vandetanib 6.5
TMX 6.3
Ixabepilone 6.2
Gefitinib 6.2
Batimastat 6.0
Batimastat 6.0
Cetuximab 6.0
NOV 5.8
Compound 18 5.7
Celebrex 5.6
Taxotere 5.6
RBT 5.4
Chlorate 5.4
Arimidex 5.4
Zileuton 5.3
Xeloda 5.3
Emodin 5.3
Panitumumab 5.2
Navelbine 5.1
Emodin 5.0
Pefloxacin 4.9
Doyle 4.9
R-gene 4.9
Flavopiridol 4.9
Tarceva 4.8
Estriol 4.8
uPA 4.7
Gleevec 4.7
Docetaxel 4.6
CDX 4.6
Zoladex 4.5
Bayer 4.5
CER 4.5
Myricetin 4.3
Zoladex 4.3
Estrogens 4.2
CDX 4.1
Filgrastim 4.1
Erlotinib 4.0
Taxol 3.9
Olive oil 3.9
Filgrastim 3.9
Imatinib 3.9
MDM 3.9
Vinorelbine 3.8
Rosuvastatin 3.7
Angiotensin II 3.7
Retinoic acid 3.6
Luteinizing 3.5
ETS 3.5
Imiquimod 3.5
DM1 3.5
IFN-gamma 3.5
IL-11 3.4
Indocyanine green 3.4
BTC 3.4
ICI 3.3
Arsenic trioxide 3.2
Lovastatin 3.2
G418 3.0
Bortezomib 3.0
DNase I 2.9
Gelatin 2.8
Bevacizumab 2.8
ETA 2.7
Rituximab 2.7
IFN-beta 2.6
ADR 2.6
-deoxyadenosine 2.5
Doxycycline 2.5
ABC 2.5
more...
Enzyme
cathepsin D 6.4
N-acetylglucosaminyltransferase III 6.0
rhomboid protease 5.8
PTPase 5.8
alpha-methylacyl-CoA racemase 5.7
ERK 5.7
CEP 5.6
phosphatidylinositol 4-kinase 5.5
CEP 5.3
N-acetylglucosaminyltransferase V 5.3
triose-phosphate isomerase 5.0
phosphatidylinositol-4,5-bisphosphate 3-kinase 4.9
thymidine phosphorylase 4.9
dihydrodiol dehydrogenase 4.8
phosphatidylinositol 3-kinase 4.7
farnesyltransferase 4.5
MEK 4.5
GRK2 4.4
protein farnesyltransferase 4.3
interstitial collagenase 4.3
topoisomerase 4.2
topoisomerase 4.2
mitogen-activated protein kinase 4.2
MMP-3 4.1
ricin 4.1
endoglycosidase H 4.1
phosphoinositide 3-kinase 4.0
prostaglandin synthetase 4.0
cytosine deaminase 4.0
farnesyltransferase 4.0
protein kinase C 4.0
prostate-specific antigen 3.9
HCS 3.9
endoproteinase Glu-C 3.8
phospholipase C 3.8
CGT 3.8
urokinase-type plasminogen activator 3.8
matrix metalloproteinase 2 3.7
STK11 3.7
protein kinase 3.6
diacylglycerol kinase 3.6
N-acetylglucosaminyltransferase 3.6
TGT 3.6
MMP 3.5
5alpha-reductase 3.5
5alpha-reductase 3.5
p80 3.5
matrix metalloproteinase 9 3.5
3-hydroxy-3-methylglutaryl-CoA reductase 3.4
PI-PLC 3.4
prostate-specific membrane antigen 3.4
thymidine kinase 3.3
heparinase 3.3
porphobilinogen deaminase 3.3
poly(A) polymerase 3.2
P-glycoprotein 3.2
mu-calpain 3.1
fatty acid desaturase 3.1
CD13 3.1
chloramphenicol acetyltransferase 3.1
S1 nuclease 3.1
insulin-degrading enzyme 3.0
enolase 3.0
ADH 3.0
PNGase F 3.0
caspase-2 3.0
MCS 3.0
peptidyl-prolyl cis-trans isomerase 3.0
microsomal epoxide hydrolase 2.9
dihydropyrimidine dehydrogenase 2.9
caspase-2 2.9
NOS 2.9
dihydrofolate reductase 2.9
cdc2 2.9
dipeptidyl peptidase IV 2.9
AMPK 2.8
phosphorylase kinase 2.8
phospholipase D 2.7
TdT 2.7
caspase-8 2.6
more...
Compound
4-quinolinecarbaldehyde 11.6
C2B5 11.0
4-quinolinecarbaldehyde 11.0
4-quinolinecarbaldehyde 10.6
Dianon 10.2
3,4,5-trihydroxybenzaldehyde 10.2
NHU 10.0
DABI 9.2
4-ethoxyphenol 9.1
Aeroplysinin-1 8.8
chlorocyclohexane 8.0
Solamargine 7.8
NEU 7.6
Tectorigenin 7.6
IDC 7.4
N-ethylurea 7.2
Azoxymethane 7.2
Kyotorphin 6.9
Herbimycin 6.8
1,2,3,4,5,6-hexachlorocyclohexane 6.7
1,2,3,4,5,6-hexachlorocyclohexane 6.6
Tuberin 6.4
FANFT 6.2
TMU 6.1
Cbl 6.1
Estramustine 6.0
Latrunculin B 5.9
BTL 5.9
BDH 5.8
TIF 5.7
Glucosylceramide 5.7
Chlorate 5.7
DFS 5.7
Phosphoserine 5.6
Geldanamycin 5.6
ENU 5.5
MBT 5.5
INT 5.4
TFF 5.4
SP-1 5.4
3-octanone 5.3
Chlorate 5.3
tyrosine 5.3
Emodin 5.2
EOC 5.2
Leflunomide 5.2
DCC 5.2
Tyrosine 5.1
BTG 5.1
Withaferin A 5.1
Tunicamycin 5.1
ethyl cyanoacetate 5.1
BTG 5.1
TCC 5.1
MDA 5.0
Tamoxifen 4.9
Anastrozole 4.9
DGE 4.9
DGE 4.9
DGE 4.9
quinazoline 4.9
quinazoline 4.9
Tamoxifen 4.9
R-gene 4.9
phosphoserine 4.8
11,12-EET 4.8
delta-HCH 4.7
1,1,2-trichloroethane 4.7
DBI 4.7
(-)-Epigallocatechin 4.7
cyclohexanecarboxamide 4.7
Rottlerin 4.7
Rottlerin 4.6
Rottlerin 4.5
Capecitabine 4.5
o,p'-DDT 4.5
Phosphatidylinositol 4.5
Emodin 4.5
BSH 4.5
HBr 4.5
more...