Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UNIPROT:P04626 (erbB-2)
5,251 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein erbB-2 5251 epidermal growth factor 1147 EGF receptor 991 p53 745 HER2 517 epidermal growth factor receptor 510 neu 497 tyrosine kinase 478 EGFR 392 Mol 391 Sep 340 estrogen receptor 317 progesterone receptor 260 proto-oncogene 243 c-myc 184 Ki-67 180 A431 174 ras 165 p185 158 EGF 139 receptor tyrosine kinase 130 nodal 124 bcl-2 115 proliferating cell nuclear antigen 115 neuregulin 108 transforming growth factor-alpha 88 transforming growth factor alpha 79 p21 75 oestrogen receptor 72 glycoprotein 71 Bcl-2 71 ERK1 71 insulin 70 hormone receptor 69 ATP 67 cathepsin D 66 extracellular signal-regulated kinase 64 threonine 63 ERK 62 collagen 62 K-ras 61 platelet-derived growth factor 60 MAPK 60 c-erbB-3 60 E-cadherin 58 erbB-3 58 cyclin D1 57 cytokeratin 55 tyrosine kinase receptor 55 TGF-alpha 54 polypeptide 54 vascular endothelial growth factor 53 IFN-gamma 53 MIB 53 cytokine 51 H-ras 49 phosphatidylinositol 3-kinase 49 c-fos 48 vimentin 48 MAP kinase 46 MEK 45 CEA 44 mitogen-activated protein 43 CD8 42 amphiregulin 42 BRCA1 42 HLA-A2 41 c-Src 40 fused 40 matrix metalloproteinase 40 mutant p53 39 p38 38 heparin-binding EGF-like growth factor 38 protein tyrosine kinase 38 ERBB2 37 AKT 36 beta-catenin 35 peroxidase 32 transmembrane protein 32 carcinoembryonic antigen 32 more...

Disease tumor 1917 cancer 1894 breast cancer 1507 carcinoma 830 metastases 339 adenocarcinoma 210 carcinogenesis 209 ovarian cancer 184 squamous cell carcinoma 151 tumorigenesis 138 MCF 138 tumor growth 130 ductal carcinoma in situ 125 tumor progression 114 epithelial ovarian cancer 101 gastric cancer 99 ductal carcinoma 94 lung cancer 92 prostate cancer 85 metastatic breast cancer 79 primary tumor 78 endometrial cancer 70 mammary tumor 69 aggressiveness 64 bladder cancer 58 non-small cell lung cancer 55 pancreatic cancer 51 colorectal cancer 49 dysplasia 43 melanoma 43 adenoma 42 lung carcinoma 37 hepatocellular carcinoma 32 carcinoma of the breast 32 comedo 32 aggression 30 cervical cancer 30 carcinoma in situ 29 glioma 28 leukemia 27 neoplastic transformation 27 colon cancer 26 glioblastoma 26 retinoblastoma 24 infiltrating ductal carcinoma 23 transitional cell carcinoma 23 pertussis 23 PDB 22 lung metastases 22 renal cell carcinoma 21 osteosarcoma 19 SCID 19 liver metastases 19 uterine cervix 18 erythroblastosis 17 Barrett's esophagus 17 invasive cancer 16 small cell lung cancer 16 Dukes 16 carcinoma of the breast 16 BLM 14 tumor angiogenesis 14 sarcoma 14 mucinous carcinoma 13 esophageal cancer 12 endometrial adenocarcinoma 12 herpes simplex 12 residual disease 12 recurrent breast cancer 12 chronic pancreatitis 12 uterus 12 neuroblastoma 11 solid tumor 11 chronic myeloid leukemia 11 multiple myeloma 11 esophageal cancer 11 papilloma 11 cirrhosis 11 APC 11 hypertension 11 more...

Symptom pain 7 chills 5 starvation 3 headache 3 rigors 3 diarrhea 3 erythema 2 HSA 2 Ill 2 nipple discharge 2 cough 2 seizures 2 anesthesia 2 abdominal pain 2 syncope 2 nipple discharge 2 chest pain 2 nausea 2 cachexia 1 No adverse effect 1 female puberty 1 nausea and vomiting 1 dry eye 1 weakness 1 vomiting 1 functional recovery 1 asthenia 1 hepatomegaly 1 peri-menopausal 1 epigastric pain 1 dyspnea 1 fatigue 1 hoarseness 1 collapse 1 overweight 1 hemoptysis 1 acidity 1

Drug Herceptin 152 IFN-gamma 53 Paraffin 39 Dermatol 31 IL-2 22 lysine 16 Gefitinib 14 CSF 14 Angiotensin II 11 MAP 11 DNase I 10 Cetuximab 10 uPA 9 ICI 9 ABC 8 Gel 8 Taxol 8 Docetaxel 7 Retinoic acid 7 Estrogens 7 Bayer 6 Imatinib 6 Gleevec 6 ETS 5 CAM 5 Taxotere 5 Asn 5 Monit 4 Cardiovasc 4 G-CSF 3 ROC 3 Emodin 3 ETA 3 Pertuzumab 3 DM1 3 ROS 3 CTX 3 vitamin E 3 p75 3 EE2 3 Rituximab 3 G418 3 IFN-beta 3 Emodin 3 -deoxyadenosine 2 TAT 2 Erlotinib 2 Bevacizumab 2 Bortezomib 2 Doyle 2 Tykerb 2 Adriamycin 2 Radicicol 2 Vitamin A 2 ADR 2 Lovastatin 2 Gelatin 2 Vandetanib 2 NOV 2 IL-11 2 Arsenic trioxide 2 NADH 2 Luteinizing 2 Leaf 2 EPA 1 BTC 1 Estriol 1 Flavopiridol 1 Zileuton 1 Filgrastim 1 DHT 1 TMX 1 BH4 1 Chlorate 1 Allergen 1 Pronase 1 CER 1 L-tyrosine 1 balanced salt solution 1 Nephron 1 more...

Enzyme ERK 814 mitogen-activated protein kinase 282 protein kinase 168 protein kinase C 129 MEK 66 cathepsin D 58 phosphatidylinositol 3-kinase 49 focal adhesion kinase 44 phospholipase C 43 peroxidase 37 topoisomerase 30 reverse transcriptase 28 topoisomerase 27 urokinase-type plasminogen activator 24 alkaline phosphatase 23 luciferase 22 glutathione S-transferase 22 caspase-3 21 P-glycoprotein 20 prostate-specific antigen 17 phosphoinositide 3-kinase 16 AMPK 14 thrombin 13 thymidine kinase 12 proteasome 12 catalase 12 APC 11 PARP 11 trypsin 10 CD10 10 cdc2 10 MMP-3 10 RNase 10 PTPase 9 phospholipase A2 9 calcineurin 9 NOS 9 ricin 9 RNase 9 beta-galactosidase 8 collagenase 8 MMP 8 chloramphenicol acetyltransferase 7 caspase-8 7 endonuclease 7 dihydrofolate reductase 7 CEP 7 glyceraldehyde-3-phosphate dehydrogenase 6 GSK 6 lactate dehydrogenase 6 CEP 6 MAP 6 acid phosphatase 6 superoxide dismutase 6 NADPH oxidase 6 RNA polymerase 6 CD13 5 thymidine phosphorylase 5 tyrosine hydroxylase 5 matrix metalloproteinase 2 5 endoglycosidase H 5 S1 nuclease 5 enolase 5 prostaglandin synthetase 5 NADPH oxidase 5 ATPase 5 phosphatidylinositol 4-kinase 5 matrix metalloproteinase 9 4 caspase-9 4 guanylate cyclase 4 farnesyltransferase 4 phospholipase D 4 farnesyltransferase 4 lipoxygenase 4 gamma-glutamyl transpeptidase 4 elastase 4 DNase 4 adenylate cyclase 3 NO synthase 3 cathepsin B 3 more...

Compound DNA 730 tyrosine 615 Dec 384 Clin 300 MDA 128 calcium 96 threonine 75 acetate 72 ATP 67 phosphate 66 serine 60 sodium 42 methionine 40 cAMP 38 MEK 37 retinoic acid 35 Phe 32 oxygen 30 alanine 28 Estrogen 28 Estrogen 28 leucine 27 formaldehyde 26 water 26 arginine 25 TNM 25 lysine 24 GTP 23 MTT 22 Tyrosine 22 glucose 22 cysteine 20 Cbl 20 sulfate 20 Ang II 19 Triton X-100 19 COS 18 Tamoxifen 18 pyrimidine 18 Tamoxifen 18 pyrimidine 18 hydrogen 15 Asp 15 silver 15 ADP 15 ADP 15 ADP 15 NH2 14 DCC 14 TPA 13 TPA 13 H2O2 13 phosphoserine 12 glutamic acid 12 Pac 12 DFS 11 manganese 11 Angiotensin II 11 Ile 11 iron 11 Insulin 11 PEG 11 iodine 11 Gly 11 valine 11 TNF 10 Phosphatidylinositol 10 bromide 10 salt 10 quinazoline 9 proline 9 ICI 9 AMP 9 quinazoline 9 IDC 9 CAM 8 urea 8 His 8 dUTP 8 zinc 8 more...

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