Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P04626 (erbB-2)
5,251 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
tumor necrosis factor (ligand) superfamily, member 12 12.6
erbB-2 12.6
SNX1A 12.6
c-erbB-3 12.2
erbB-3 11.6
Sp2 transcription factor 11.6
Opioid binding protein/cell adhesion molecule-like 11.6
apoptosis repressor with CARD domain 11.0
p185 10.9
mutant p53 tumor suppressor 10.8
CBE1 10.6
herstatin 10.6
ERBB3 protein 10.6
amplified in osteosarcoma 10.6
Herstatin 10.5
c-ros-1 10.2
RING4 10.2
MUC11 10.2
CAB1 10.0
NAPG 10.0
putative transmembrane receptor 10.0
EGF receptor 9.9
NRG-4 9.8
neu 9.6
COLM 9.6
chemokine BRAK 9.6
Ski oncoprotein 9.6
Eps15R 9.6
TBC1D9 9.6
RABEP1 9.6
VPS37C 9.4
NB3 9.4
VPS37B 9.4
STARD10 9.4
MAGE2 9.2
Telethonin 9.1
rlf 9.1
Vascular endothelial growth factor D 9.1
GPR30 protein 9.0
focal adhesion kinase 1 9.0
more...
Disease
Basal cell carcinoma with sebaceous differentiation 12.6
Malignant insulinoma 9.6
Laryngeal papilloma 9.6
Psoriatic plaque 9.4
PanIN-1A 9.4
Paget's disease of the nipple 9.3
comedo carcinoma 9.2
Secretory carcinoma of the breast 9.1
stage IIB cervical cancer 9.1
MDD2 9.1
Small cell osteosarcoma 8.6
comedo 8.5
Gastric dysplasia 8.4
PanIN-1B 8.3
Salivary duct carcinoma 8.2
stage II NSCLC 8.0
PanIN-1 7.8
uterine carcinosarcoma 7.8
PanIN-3 7.7
stage IB cervical cancer 7.7
ductal carcinoma in situ 7.6
DA4 7.6
benign proliferative breast disease 7.6
cutaneous leiomyoma 7.5
infiltrating ductal carcinoma 7.5
Extramammary Paget's disease 7.4
stage III breast cancer 7.4
Endometrioid carcinoma 7.4
Liver mass 7.3
ductal carcinoma 7.3
Pleomorphic carcinoma 7.2
LCIS 7.2
erythroblastosis 7.1
ovarian tumors of low malignant potential 7.1
VIN III 7.1
PanIN-2 7.0
metaplastic carcinoma 7.0
Peritoneal metastases 7.0
metastatic endometrial cancer 6.9
stage D prostate cancer 6.9
more...
Symptom
female puberty 5.6
peri-menopausal 5.1
nipple discharge 4.5
rigors 4.5
nipple discharge 4.5
No adverse effect 4.2
chills 2.8
HSA 2.0
dry eye 1.2
asthenia 1.2
hoarseness 1.0
epigastric pain 0.8
syncope 0.4
Ill 0.1
cachexia 0.1
hepatomegaly 0.1
hemoptysis -0.0
erythema -0.1
starvation -0.5
chest pain -0.5
nausea and vomiting -0.7
nausea -1.0
cough -1.0
functional recovery -1.1
acidity -1.3
abdominal pain -1.4
headache -1.6
diarrhea -1.7
overweight -2.1
dyspnea -2.2
collapse -2.2
vomiting -2.4
pain -2.6
weakness -2.6
seizures -2.7
fatigue -3.1
anesthesia -3.2
Drug
Gris-PEG 9.4
CEA-Scan 9.2
Herceptin 8.7
Tykerb 7.8
Radicicol 7.5
Pertuzumab 7.1
Paraffin 6.8
Ontak 6.7
Ontak 6.7
Vandetanib 6.5
TMX 6.3
Ixabepilone 6.2
Gefitinib 6.2
Batimastat 6.0
Batimastat 6.0
Cetuximab 6.0
NOV 5.8
Compound 18 5.7
Celebrex 5.6
Taxotere 5.6
RBT 5.4
Chlorate 5.4
Arimidex 5.4
Zileuton 5.3
Xeloda 5.3
Emodin 5.3
Panitumumab 5.2
Navelbine 5.1
Emodin 5.0
Pefloxacin 4.9
Doyle 4.9
R-gene 4.9
Flavopiridol 4.9
Tarceva 4.8
Estriol 4.8
uPA 4.7
Gleevec 4.7
Docetaxel 4.6
CDX 4.6
Zoladex 4.5
more...
Enzyme
cathepsin D 6.4
N-acetylglucosaminyltransferase III 6.0
rhomboid protease 5.8
PTPase 5.8
alpha-methylacyl-CoA racemase 5.7
ERK 5.7
CEP 5.6
phosphatidylinositol 4-kinase 5.5
CEP 5.3
N-acetylglucosaminyltransferase V 5.3
triose-phosphate isomerase 5.0
phosphatidylinositol-4,5-bisphosphate 3-kinase 4.9
thymidine phosphorylase 4.9
dihydrodiol dehydrogenase 4.8
phosphatidylinositol 3-kinase 4.7
farnesyltransferase 4.5
MEK 4.5
GRK2 4.4
protein farnesyltransferase 4.3
interstitial collagenase 4.3
topoisomerase 4.2
topoisomerase 4.2
mitogen-activated protein kinase 4.2
MMP-3 4.1
ricin 4.1
endoglycosidase H 4.1
phosphoinositide 3-kinase 4.0
prostaglandin synthetase 4.0
cytosine deaminase 4.0
farnesyltransferase 4.0
protein kinase C 4.0
prostate-specific antigen 3.9
HCS 3.9
endoproteinase Glu-C 3.8
phospholipase C 3.8
CGT 3.8
urokinase-type plasminogen activator 3.8
matrix metalloproteinase 2 3.7
STK11 3.7
protein kinase 3.6
more...
Compound
4-quinolinecarbaldehyde 11.6
4-quinolinecarbaldehyde 11.0
C2B5 11.0
4-quinolinecarbaldehyde 10.6
3,4,5-trihydroxybenzaldehyde 10.2
Dianon 10.2
NHU 10.0
DABI 9.2
4-ethoxyphenol 9.1
Aeroplysinin-1 8.8
chlorocyclohexane 8.0
Solamargine 7.8
NEU 7.6
Tectorigenin 7.6
IDC 7.4
N-ethylurea 7.2
Azoxymethane 7.2
Kyotorphin 6.9
Herbimycin 6.8
1,2,3,4,5,6-hexachlorocyclohexane 6.7
1,2,3,4,5,6-hexachlorocyclohexane 6.6
Tuberin 6.4
FANFT 6.2
TMU 6.1
Cbl 6.1
Estramustine 6.0
Latrunculin B 5.9
BTL 5.9
BDH 5.8
TIF 5.7
Glucosylceramide 5.7
Chlorate 5.7
DFS 5.7
Phosphoserine 5.6
Geldanamycin 5.6
ENU 5.5
MBT 5.5
INT 5.4
TFF 5.4
SP-1 5.4
more...