Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UNIPROT:P04626 (erbB-2)
5,251 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein erbB-2 5251 epidermal growth factor 1147 EGF receptor 991 p53 745 HER2 517 epidermal growth factor receptor 510 neu 497 tyrosine kinase 478 EGFR 392 Mol 391 Sep 340 estrogen receptor 317 progesterone receptor 260 proto-oncogene 243 c-myc 184 Ki-67 180 A431 174 ras 165 p185 158 EGF 139 receptor tyrosine kinase 130 nodal 124 proliferating cell nuclear antigen 115 bcl-2 115 neuregulin 108 transforming growth factor-alpha 88 transforming growth factor alpha 79 p21 75 oestrogen receptor 72 ERK1 71 glycoprotein 71 Bcl-2 71 insulin 70 hormone receptor 69 ATP 67 cathepsin D 66 extracellular signal-regulated kinase 64 threonine 63 ERK 62 collagen 62 more...

Disease tumor 1917 cancer 1894 breast cancer 1507 carcinoma 830 metastases 339 adenocarcinoma 210 carcinogenesis 209 ovarian cancer 184 squamous cell carcinoma 151 tumorigenesis 138 MCF 138 tumor growth 130 ductal carcinoma in situ 125 tumor progression 114 epithelial ovarian cancer 101 gastric cancer 99 ductal carcinoma 94 lung cancer 92 prostate cancer 85 metastatic breast cancer 79 primary tumor 78 endometrial cancer 70 mammary tumor 69 aggressiveness 64 bladder cancer 58 non-small cell lung cancer 55 pancreatic cancer 51 colorectal cancer 49 melanoma 43 dysplasia 43 adenoma 42 lung carcinoma 37 hepatocellular carcinoma 32 carcinoma of the breast 32 comedo 32 cervical cancer 30 aggression 30 carcinoma in situ 29 glioma 28 neoplastic transformation 27 more...

Symptom pain 7 chills 5 starvation 3 headache 3 rigors 3 diarrhea 3 erythema 2 HSA 2 Ill 2 nipple discharge 2 cough 2 seizures 2 anesthesia 2 abdominal pain 2 syncope 2 nipple discharge 2 chest pain 2 nausea 2 cachexia 1 No adverse effect 1 female puberty 1 nausea and vomiting 1 dry eye 1 weakness 1 vomiting 1 functional recovery 1 asthenia 1 hepatomegaly 1 peri-menopausal 1 epigastric pain 1 dyspnea 1 fatigue 1 hoarseness 1 collapse 1 overweight 1 hemoptysis 1 acidity 1

Drug Herceptin 152 IFN-gamma 53 Paraffin 39 Dermatol 31 IL-2 22 lysine 16 CSF 14 Gefitinib 14 Angiotensin II 11 MAP 11 DNase I 10 Cetuximab 10 ICI 9 uPA 9 ABC 8 Gel 8 Taxol 8 Estrogens 7 Docetaxel 7 Retinoic acid 7 Imatinib 6 Gleevec 6 Bayer 6 ETS 5 Taxotere 5 CAM 5 Asn 5 Monit 4 Cardiovasc 4 G-CSF 3 p75 3 ETA 3 ROC 3 Emodin 3 vitamin E 3 DM1 3 CTX 3 G418 3 EE2 3 Rituximab 3 more...

Enzyme ERK 814 mitogen-activated protein kinase 282 protein kinase 168 protein kinase C 129 MEK 66 cathepsin D 58 phosphatidylinositol 3-kinase 49 focal adhesion kinase 44 phospholipase C 43 peroxidase 37 topoisomerase 30 reverse transcriptase 28 topoisomerase 27 urokinase-type plasminogen activator 24 alkaline phosphatase 23 glutathione S-transferase 22 luciferase 22 caspase-3 21 P-glycoprotein 20 prostate-specific antigen 17 phosphoinositide 3-kinase 16 AMPK 14 thrombin 13 catalase 12 thymidine kinase 12 proteasome 12 PARP 11 APC 11 MMP-3 10 cdc2 10 CD10 10 trypsin 10 RNase 10 ricin 9 NOS 9 PTPase 9 phospholipase A2 9 calcineurin 9 RNase 9 collagenase 8 more...

Compound DNA 730 tyrosine 615 Dec 384 Clin 300 MDA 128 calcium 96 threonine 75 acetate 72 ATP 67 phosphate 66 serine 60 sodium 42 methionine 40 cAMP 38 MEK 37 retinoic acid 35 Phe 32 oxygen 30 Estrogen 28 alanine 28 Estrogen 28 leucine 27 formaldehyde 26 water 26 arginine 25 TNM 25 lysine 24 GTP 23 Tyrosine 22 MTT 22 glucose 22 cysteine 20 sulfate 20 Cbl 20 Triton X-100 19 Ang II 19 COS 18 pyrimidine 18 pyrimidine 18 Tamoxifen 18 more...

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