Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P04626 (erbB-2)
 5,251 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
erbB-2 5251
epidermal growth factor 1147
EGF receptor 991
p53 745
HER2 517
epidermal growth factor receptor 510
neu 497
tyrosine kinase 478
EGFR 392
Mol 391
Sep 340
estrogen receptor 317
progesterone receptor 260
proto-oncogene 243
c-myc 184
Ki-67 180
A431 174
ras 165
p185 158
EGF 139
more...
Disease
tumor 1917
cancer 1894
breast cancer 1507
carcinoma 830
metastases 339
adenocarcinoma 210
carcinogenesis 209
ovarian cancer 184
squamous cell carcinoma 151
MCF 138
tumorigenesis 138
tumor growth 130
ductal carcinoma in situ 125
tumor progression 114
epithelial ovarian cancer 101
gastric cancer 99
ductal carcinoma 94
lung cancer 92
prostate cancer 85
metastatic breast cancer 79
more...
Symptom
pain 7
chills 5
diarrhea 3
headache 3
rigors 3
starvation 3
Ill 2
nipple discharge 2
nipple discharge 2
syncope 2
seizures 2
HSA 2
abdominal pain 2
cough 2
erythema 2
anesthesia 2
chest pain 2
nausea 2
hepatomegaly 1
hoarseness 1
more...
Drug
Herceptin 152
IFN-gamma 53
Paraffin 39
Dermatol 31
IL-2 22
lysine 16
CSF 14
Gefitinib 14
Angiotensin II 11
MAP 11
DNase I 10
Cetuximab 10
ICI 9
uPA 9
ABC 8
Gel 8
Taxol 8
Retinoic acid 7
Estrogens 7
Docetaxel 7
more...
Enzyme
ERK 814
mitogen-activated protein kinase 282
protein kinase 168
protein kinase C 129
MEK 66
cathepsin D 58
phosphatidylinositol 3-kinase 49
focal adhesion kinase 44
phospholipase C 43
peroxidase 37
topoisomerase 30
reverse transcriptase 28
topoisomerase 27
urokinase-type plasminogen activator 24
alkaline phosphatase 23
glutathione S-transferase 22
luciferase 22
caspase-3 21
P-glycoprotein 20
prostate-specific antigen 17
more...
Compound
DNA 730
tyrosine 615
Dec 384
Clin 300
MDA 128
calcium 96
threonine 75
acetate 72
ATP 67
phosphate 66
serine 60
sodium 42
methionine 40
cAMP 38
MEK 37
retinoic acid 35
Phe 32
oxygen 30
Estrogen 28
Estrogen 28
more...