Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P04626 (
erbB-2
)
5,251
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Benign and malignant cartilage tumours as well as normal cartilage were stained immunohistochemically with antibodies raised to a synthetic peptide from the sequence of the c-
erbB-2
protein. Positive staining was present in 18/23 of the chondrosarcomas and in one case of
osteochondroma
. Normal and benign neoplastic cartilage tissues revealed negative results. It is concluded that expression of the c-
erbB-2
protein may contribute to cell transformation in chondrosarcomas; it is not apparent whether the expression of c-
erbB-2
protein in chondrosarcomas characterizes a subpopulation of different prognostic significance.
...
PMID:Immunohistochemical detection of the c-erbB-2 proto-oncogene product in normal, benign and malignant cartilage tissues. 196 19
