Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: UNIPROT:P04179 (MnSOD)
2,777 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein MnSOD 2777 superoxide dismutase 1060 catalase 735 SOD 634 glutathione peroxidase 419 GSH 256 antioxidant enzyme 230 Mol 223 Sep 187 manganese superoxide dismutase 161 ROS 153 glutathione reductase 150 SOD2 149 CAT 134 Superoxide dismutase 117 caspase-3 109 Bcl-2 94 insulin 88 SOD1 86 TNF 81 inducible nitric oxide synthase 79 p53 68 ATP 68 nitric oxide synthase 64 cytochrome c 63 Catalase 61 cytokine 59 heme oxygenase-1 58 IL-6 56 tumor necrosis factor 56 peroxidase 55 Nrf2 53 xanthine oxidase 51 HSP70 49 glutathione peroxidase 1 43 HO-1 43 lipopolysaccharide 42 Cu/Zn superoxide dismutase 42 eNOS 41 GST 37 glutathione S-transferase 36 thioredoxin 33 neuronal nitric oxide synthase 32 p38 32 aconitase 31 SOD3 31 NADPH 30 JNK 29 MAPK 29 ERK 28 COX-2 28 PGC 27 SIRT3 27 APE1 26 ERK1 26 metallothionein 25 LPS 25 caspase-9 24 GSTM1 24 citrate synthase 23 myeloperoxidase 23 cyclooxygenase-2 23 ADP 22 CA1 22 endoplasmic reticulum 22 GPX1 22 Glutathione peroxidase 21 heat shock protein 21 NQO1 21 cytochrome 21 Manganese superoxide dismutase 21 polypeptide 20 lactate dehydrogenase 20 PARP 20 alanine aminotransferase 20 endothelial nitric oxide synthase 20 p65 20 IFN 20 cytochrome c oxidase 19 GSTT1 19 more...

Disease GSH 256 cancer 188 ischemia 116 tumor 115 diabetes 90 breast cancer 44 carcinogenesis 41 Alzheimer's disease 41 hyperglycemia 35 stroke 34 hepatocellular carcinoma 34 Parkinson's disease 33 obesity 31 atherosclerosis 30 hypertension 29 carcinoma 26 heart failure 26 cold 24 amyotrophic lateral sclerosis 23 cardiomyopathy 22 cerebral ischemia 21 neuroblastoma 21 MCF 21 depression 17 type 2 diabetes 17 cardiovascular disease 16 adenocarcinoma 16 melanoma 15 prostate cancer 15 myocardial ischemia 15 sepsis 15 sepsis 15 SDS 15 NAME 13 lung cancer 13 tumor growth 12 glioma 12 diabetic retinopathy 12 dilated cardiomyopathy 11 leukemia 11 squamous cell carcinoma 11 type 1 diabetes 11 colorectal cancer 11 cognitive impairment 11 myocardial infarction 10 lung carcinoma 10 hypercholesterolemia 10 cirrhosis 10 gastric cancer 10 dementia 9 tumorigenesis 9 HIV 9 colon cancer 9 renal disease 9 tumor progression 9 iron overload 8 asthma 8 Down syndrome 8 diabetic nephropathy 8 acute myocardial infarction 8 B-cell lymphoma 7 OPA1 7 fatty liver 7 epilepsy 7 plaque 7 tardive dyskinesia 7 glioblastoma 7 hyperlipidemia 6 FAS 6 Chagas 6 liver disease 6 Copper deficiency 6 coronary artery disease 6 mitochondrial disease 6 parkinsonism 6 pheochromocytoma 6 subarachnoid hemorrhage 6 Diaphragm 6 schizophrenia 5 chronic disease 5 more...

Symptom hyperoxia 49 starvation 14 seizures 11 fatigue 10 anesthesia 6 collapse 6 exhaustion 6 pain 5 ophthalmoplegia 5 ataxia 5 angina 4 acidity 4 acute stress 4 weakness 3 tremor 3 hypothermia 3 functional recovery 3 chills 2 cachexia 2 cerebellar ataxia 1 tonic-clonic seizure 1 muscle rigidity 1 constipation 1 Decreased activity 1 respiratory distress 1 Catch 1 dyspnea 1 Mills 1 dystonia 1 cancer pain 1 menopausal symptoms 1 Diaphragmatic weakness 1 bradykinesia 1 spasm 1

Drug ROS 153 ascorbate 63 vitamin E 37 lysine 23 NADH 18 Glutathione 14 Vitamin E 12 MAP 12 Dermatol 11 Parkin 8 Parkin 8 Ethanol 7 Capsicum 7 Indomethacin 7 Adriamycin 6 Cardiovasc 6 Nephron 5 IL-2 5 Gel 5 nitroglycerin 5 Nitric Oxide 4 Heme 4 Asn 3 lactose 3 Vitamin A 3 TTC 3 CSF 3 FLP 3 Nephron 3 Leaf 3 G418 2 CoCl2 2 Desferal 2 Vitamin K 2 Alanine 2 Asthma 2 Nimesulide 2 Pilocarpine 2 EE2 2 caffeine 2 PCB 2 CoCl2 2 ALA 2 Desferal 2 IFN-gamma 2 ABC 2 Ciprofibrate 2 Photofrin 2 ETS 1 Levosimendan 1 Allergen 1 ZnCl2 1 SiO2 1 Pyridostigmine bromide 1 2-Methoxyestradiol 1 CTC 1 NBT 1 Frontal 1 Ranolazine 1 linolenate 1 Salicylate 1 Ranolazine 1 ZnCl2 1 Bezafibrate 1 Ketoconazole 1 Pyridostigmine bromide 1 Tirapazamine 1 Fluorescein 1 Sorafenib 1 Molsidomine 1 SMP 1 Beraprost sodium 1 beta-Galactosidase 1 ETA 1 Rosiglitazone 1 DMI 1 Bifidobacterium 1 Aloe 1 Tacrolimus 1 FAD 1 more...

Enzyme superoxide dismutase 1743 catalase 832 glutathione peroxidase 423 glutathione reductase 154 peroxidase 87 mitogen-activated protein kinase 82 caspase-3 79 glutathione S-transferase 76 NADPH oxidase 65 complex I 53 NADPH oxidase 50 xanthine oxidase 49 ascorbate peroxidase 42 ERK 36 NO synthase 32 aconitase 31 alanine aminotransferase 30 NQO1 28 AMP-activated protein kinase 27 protein kinase 24 PARP 24 citrate synthase 23 glucose-6-phosphate dehydrogenase 22 cytochrome oxidase 22 protein kinase C 22 lactate dehydrogenase 22 caspase-9 21 aspartate aminotransferase 19 AMPK 19 AMPK 19 succinate dehydrogenase 19 ATPase 19 NOS 19 peroxiredoxin 19 heme oxygenase 18 reverse transcriptase 16 lysozyme 15 ATP synthase 14 creatine kinase 14 luciferase 13 gamma-glutamylcysteine synthetase 11 diaphorase 11 isocitrate dehydrogenase 10 alkaline phosphatase 10 dehydroascorbate reductase 10 MEK 10 focal adhesion kinase 10 ceruloplasmin 9 tyrosine hydroxylase 9 CPR 9 AST 9 SOR 9 caspase-8 9 thioredoxin reductase 8 PKG 8 glutamine synthetase 8 acetylcholinesterase 8 glyceraldehyde-3-phosphate dehydrogenase 8 phospholipid hydroperoxide glutathione peroxidase 8 MAP 8 acid phosphatase 8 monoamine oxidase 7 isocitrate dehydrogenase 7 malate dehydrogenase 7 beta-galactosidase 7 DCF 6 IKK 6 trypsin 6 NADH dehydrogenase 6 lipoxygenase 6 arginase 6 glyceraldehyde-3-phosphate dehydrogenase 6 gamma-glutamyl transpeptidase 5 aldose reductase 5 ACE 5 proteasome 5 glyceraldehyde-3-phosphate dehydrogenase 5 aldehyde dehydrogenase 5 TOR 5 RNA polymerase 5 more...

Compound oxygen 811 manganese 306 DNA 304 GSH 267 GSH 267 hydrogen 217 Dec 216 copper 206 zinc 166 H2O2 162 superoxide radical 148 nitric oxide 135 CAT 134 CAT 134 CAT 134 iron 122 water 121 glucose 110 TNF 81 MDA 75 ATP 68 GSSG 65 Clin 49 nitrogen 49 sodium 49 calcium 46 salt 46 cysteine 44 ethanol 42 N-acetylcysteine 41 alanine 37 tyrosine 37 cadmium 37 cyanide 32 phosphate 31 selenium 31 NADPH 30 NADPH 30 8-OHdG 27 lysine 27 arginine 26 acetate 25 PEG 25 sulfate 23 ADP 22 ADP 22 ADP 22 ammonium 22 His 21 glutamate 20 NAD 20 proline 20 NADH 18 methionine 18 potassium 17 SDS 17 NAD 16 nicotinamide 16 galactose 16 PEG 16 Resveratrol 15 MTT 15 serine 15 nitrate 15 glutamine 14 Adriamycin 14 Melatonin 13 Panam 13 urea 13 Ascorbic acid 13 Vitamin E 13 Insulin 12 threonine 11 creatinine 11 MAP 11 nickel 11 2-nonenal 11 cGMP 11 hydroxide 10 HCl 10 more...

---