Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P04179 (MnSOD)
2,777 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MnSOD 2777
superoxide dismutase 1060
catalase 735
SOD 634
glutathione peroxidase 419
GSH 256
antioxidant enzyme 230
Mol 223
Sep 187
manganese superoxide dismutase 161
ROS 153
glutathione reductase 150
SOD2 149
CAT 134
Superoxide dismutase 117
caspase-3 109
Bcl-2 94
insulin 88
SOD1 86
TNF 81
inducible nitric oxide synthase 79
p53 68
ATP 68
nitric oxide synthase 64
cytochrome c 63
Catalase 61
cytokine 59
heme oxygenase-1 58
tumor necrosis factor 56
IL-6 56
peroxidase 55
Nrf2 53
xanthine oxidase 51
HSP70 49
glutathione peroxidase 1 43
HO-1 43
lipopolysaccharide 42
Cu/Zn superoxide dismutase 42
eNOS 41
GST 37
more...
Disease
GSH 256
cancer 188
ischemia 116
tumor 115
diabetes 90
breast cancer 44
Alzheimer's disease 41
carcinogenesis 41
hyperglycemia 35
hepatocellular carcinoma 34
stroke 34
Parkinson's disease 33
obesity 31
atherosclerosis 30
hypertension 29
carcinoma 26
heart failure 26
cold 24
amyotrophic lateral sclerosis 23
cardiomyopathy 22
neuroblastoma 21
MCF 21
cerebral ischemia 21
type 2 diabetes 17
depression 17
cardiovascular disease 16
adenocarcinoma 16
SDS 15
sepsis 15
prostate cancer 15
myocardial ischemia 15
melanoma 15
sepsis 15
lung cancer 13
NAME 13
tumor growth 12
glioma 12
diabetic retinopathy 12
leukemia 11
type 1 diabetes 11
more...
Symptom
hyperoxia 49
starvation 14
seizures 11
fatigue 10
anesthesia 6
collapse 6
exhaustion 6
pain 5
ophthalmoplegia 5
ataxia 5
angina 4
acidity 4
acute stress 4
weakness 3
tremor 3
hypothermia 3
functional recovery 3
chills 2
cachexia 2
cerebellar ataxia 1
tonic-clonic seizure 1
muscle rigidity 1
constipation 1
Decreased activity 1
respiratory distress 1
Catch 1
dyspnea 1
Mills 1
dystonia 1
cancer pain 1
menopausal symptoms 1
Diaphragmatic weakness 1
bradykinesia 1
spasm 1
Drug
ROS 153
ascorbate 63
vitamin E 37
lysine 23
NADH 18
Glutathione 14
MAP 12
Vitamin E 12
Dermatol 11
Parkin 8
Parkin 8
Indomethacin 7
Capsicum 7
Ethanol 7
Cardiovasc 6
Adriamycin 6
Nephron 5
IL-2 5
Gel 5
nitroglycerin 5
Nitric Oxide 4
Heme 4
lactose 3
CSF 3
FLP 3
Leaf 3
Vitamin A 3
Nephron 3
Asn 3
TTC 3
Ciprofibrate 2
Desferal 2
Desferal 2
ALA 2
IFN-gamma 2
Asthma 2
Alanine 2
G418 2
Nimesulide 2
EE2 2
more...
Enzyme
superoxide dismutase 1743
catalase 832
glutathione peroxidase 423
glutathione reductase 154
peroxidase 87
mitogen-activated protein kinase 82
caspase-3 79
glutathione S-transferase 76
NADPH oxidase 65
complex I 53
NADPH oxidase 50
xanthine oxidase 49
ascorbate peroxidase 42
ERK 36
NO synthase 32
aconitase 31
alanine aminotransferase 30
NQO1 28
AMP-activated protein kinase 27
protein kinase 24
PARP 24
citrate synthase 23
protein kinase C 22
glucose-6-phosphate dehydrogenase 22
cytochrome oxidase 22
lactate dehydrogenase 22
caspase-9 21
AMPK 19
aspartate aminotransferase 19
succinate dehydrogenase 19
NOS 19
AMPK 19
ATPase 19
peroxiredoxin 19
heme oxygenase 18
reverse transcriptase 16
lysozyme 15
creatine kinase 14
ATP synthase 14
luciferase 13
more...
Compound
oxygen 811
manganese 306
DNA 304
GSH 267
GSH 267
hydrogen 217
Dec 216
copper 206
zinc 166
H2O2 162
superoxide radical 148
nitric oxide 135
CAT 134
CAT 134
CAT 134
iron 122
water 121
glucose 110
TNF 81
MDA 75
ATP 68
GSSG 65
Clin 49
nitrogen 49
sodium 49
calcium 46
salt 46
cysteine 44
ethanol 42
N-acetylcysteine 41
tyrosine 37
alanine 37
cadmium 37
cyanide 32
phosphate 31
selenium 31
NADPH 30
NADPH 30
8-OHdG 27
lysine 27
more...