Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P04179 (
MnSOD
)
2,777
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
MnSOD
2777
superoxide dismutase
1060
catalase
735
SOD
634
glutathione peroxidase
419
GSH
256
antioxidant enzyme
230
Mol
223
Sep
187
manganese superoxide dismutase
161
ROS
153
glutathione reductase
150
SOD2
149
CAT
134
Superoxide dismutase
117
caspase-3
109
Bcl-2
94
insulin
88
SOD1
86
TNF
81
inducible nitric oxide synthase
79
p53
68
ATP
68
nitric oxide synthase
64
cytochrome c
63
Catalase
61
cytokine
59
heme oxygenase-1
58
tumor necrosis factor
56
IL-6
56
peroxidase
55
Nrf2
53
xanthine oxidase
51
HSP70
49
glutathione peroxidase 1
43
HO-1
43
lipopolysaccharide
42
Cu/Zn superoxide dismutase
42
eNOS
41
GST
37
more...
Disease
GSH
256
cancer
188
ischemia
116
tumor
115
diabetes
90
breast cancer
44
Alzheimer's disease
41
carcinogenesis
41
hyperglycemia
35
hepatocellular carcinoma
34
stroke
34
Parkinson's disease
33
obesity
31
atherosclerosis
30
hypertension
29
carcinoma
26
heart failure
26
cold
24
amyotrophic lateral sclerosis
23
cardiomyopathy
22
neuroblastoma
21
MCF
21
cerebral ischemia
21
type 2 diabetes
17
depression
17
cardiovascular disease
16
adenocarcinoma
16
SDS
15
sepsis
15
prostate cancer
15
myocardial ischemia
15
melanoma
15
sepsis
15
lung cancer
13
NAME
13
tumor growth
12
glioma
12
diabetic retinopathy
12
leukemia
11
type 1 diabetes
11
more...
Symptom
hyperoxia
49
starvation
14
seizures
11
fatigue
10
anesthesia
6
collapse
6
exhaustion
6
pain
5
ophthalmoplegia
5
ataxia
5
angina
4
acidity
4
acute stress
4
weakness
3
tremor
3
hypothermia
3
functional recovery
3
chills
2
cachexia
2
cerebellar ataxia
1
tonic-clonic seizure
1
muscle rigidity
1
constipation
1
Decreased activity
1
respiratory distress
1
Catch
1
dyspnea
1
Mills
1
dystonia
1
cancer pain
1
menopausal symptoms
1
Diaphragmatic weakness
1
bradykinesia
1
spasm
1
Drug
ROS
153
ascorbate
63
vitamin E
37
lysine
23
NADH
18
Glutathione
14
MAP
12
Vitamin E
12
Dermatol
11
Parkin
8
Parkin
8
Indomethacin
7
Capsicum
7
Ethanol
7
Cardiovasc
6
Adriamycin
6
Nephron
5
IL-2
5
Gel
5
nitroglycerin
5
Nitric Oxide
4
Heme
4
lactose
3
CSF
3
FLP
3
Leaf
3
Vitamin A
3
Nephron
3
Asn
3
TTC
3
Ciprofibrate
2
Desferal
2
Desferal
2
ALA
2
IFN-gamma
2
Asthma
2
Alanine
2
G418
2
Nimesulide
2
EE2
2
more...
Enzyme
superoxide dismutase
1743
catalase
832
glutathione peroxidase
423
glutathione reductase
154
peroxidase
87
mitogen-activated protein kinase
82
caspase-3
79
glutathione S-transferase
76
NADPH oxidase
65
complex I
53
NADPH oxidase
50
xanthine oxidase
49
ascorbate peroxidase
42
ERK
36
NO synthase
32
aconitase
31
alanine aminotransferase
30
NQO1
28
AMP-activated protein kinase
27
protein kinase
24
PARP
24
citrate synthase
23
protein kinase C
22
glucose-6-phosphate dehydrogenase
22
cytochrome oxidase
22
lactate dehydrogenase
22
caspase-9
21
AMPK
19
aspartate aminotransferase
19
succinate dehydrogenase
19
NOS
19
AMPK
19
ATPase
19
peroxiredoxin
19
heme oxygenase
18
reverse transcriptase
16
lysozyme
15
creatine kinase
14
ATP synthase
14
luciferase
13
more...
Compound
oxygen
811
manganese
306
DNA
304
GSH
267
GSH
267
hydrogen
217
Dec
216
copper
206
zinc
166
H2O2
162
superoxide radical
148
nitric oxide
135
CAT
134
CAT
134
CAT
134
iron
122
water
121
glucose
110
TNF
81
MDA
75
ATP
68
GSSG
65
Clin
49
nitrogen
49
sodium
49
calcium
46
salt
46
cysteine
44
ethanol
42
N-acetylcysteine
41
tyrosine
37
alanine
37
cadmium
37
cyanide
32
phosphate
31
selenium
31
NADPH
30
NADPH
30
8-OHdG
27
lysine
27
more...