Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P04179 (MnSOD)
 2,777 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MnSOD 2777
superoxide dismutase 1060
catalase 735
SOD 634
glutathione peroxidase 419
GSH 256
antioxidant enzyme 230
Mol 223
Sep 187
manganese superoxide dismutase 161
ROS 153
glutathione reductase 150
SOD2 149
CAT 134
Superoxide dismutase 117
caspase-3 109
Bcl-2 94
insulin 88
SOD1 86
TNF 81
inducible nitric oxide synthase 79
p53 68
ATP 68
nitric oxide synthase 64
cytochrome c 63
Catalase 61
cytokine 59
heme oxygenase-1 58
IL-6 56
tumor necrosis factor 56
peroxidase 55
Nrf2 53
xanthine oxidase 51
HSP70 49
glutathione peroxidase 1 43
HO-1 43
lipopolysaccharide 42
Cu/Zn superoxide dismutase 42
eNOS 41
GST 37
glutathione S-transferase 36
thioredoxin 33
neuronal nitric oxide synthase 32
p38 32
aconitase 31
SOD3 31
NADPH 30
JNK 29
MAPK 29
COX-2 28
ERK 28
PGC 27
SIRT3 27
APE1 26
ERK1 26
LPS 25
metallothionein 25
GSTM1 24
caspase-9 24
myeloperoxidase 23
citrate synthase 23
cyclooxygenase-2 23
ADP 22
CA1 22
endoplasmic reticulum 22
GPX1 22
Manganese superoxide dismutase 21
cytochrome 21
NQO1 21
heat shock protein 21
Glutathione peroxidase 21
endothelial nitric oxide synthase 20
PARP 20
alanine aminotransferase 20
p65 20
lactate dehydrogenase 20
polypeptide 20
IFN 20
cytochrome c oxidase 19
GSTT1 19
AMPK 19
manganese-containing superoxide dismutase 19
IL-1 18
glucose-6-phosphate dehydrogenase 18
NADH 18
LDH 17
IL-8 17
ATPase 17
AKT 17
collagen 17
SIRT1 17
IL-10 17
GSTP1 17
AP-1 17
UCP2 17
LC3 16
interferon 16
NAD 16
extracellular superoxide dismutase 16
apoE 15
SDS 15
dimeric 15
carp 15
sirtuin 15
lysozyme 15
histone 15
GSR 15
TNF-alpha 15
microsomal 15
reductase 14
TFAM 14
aspartate aminotransferase 14
ATP synthase 14
EC-SOD 14
PEG 14
mTOR 13
p21 13
tumor necrosis factor alpha 13
Pseudomonas 13
caspase-8 13
NAC 13
DAF 12
EPR 12
albumin 12
peroxisome proliferator-activated receptor 12
interleukin-6 12
thymus 12
BAX 12
cytochrome P450 12
xenobiotic 12
erythroid 11
VEGF 11
HNE 11
hemoglobin 11
p22 11
PI3K 11
ubiquitin 11
phospholipid hydroperoxide glutathione peroxidase 11
peroxisome proliferator-activated receptor gamma 11
Gen 11
ICAM-1 11
creatine kinase 10
amyloid precursor protein 10
uncoupling protein 1 10
Bak 10
AIF 10
glutathione transferase 10
alkaline phosphatase 10
NMR 9
TLR4 9
occludin 9
CAT1 9
glycoprotein 9
ferritin 9
COMT 9
p62 9
glial fibrillary acidic protein 9
GCS 9
NOX4 9
DT-diaphorase 9
more...
Disease
GSH 256
cancer 188
ischemia 116
tumor 115
diabetes 90
breast cancer 44
carcinogenesis 41
Alzheimer's disease 41
hyperglycemia 35
hepatocellular carcinoma 34
stroke 34
Parkinson's disease 33
obesity 31
atherosclerosis 30
hypertension 29
heart failure 26
carcinoma 26
cold 24
amyotrophic lateral sclerosis 23
cardiomyopathy 22
neuroblastoma 21
cerebral ischemia 21
MCF 21
type 2 diabetes 17
depression 17
adenocarcinoma 16
cardiovascular disease 16
sepsis 15
SDS 15
sepsis 15
melanoma 15
prostate cancer 15
myocardial ischemia 15
lung cancer 13
NAME 13
glioma 12
diabetic retinopathy 12
tumor growth 12
dilated cardiomyopathy 11
cognitive impairment 11
leukemia 11
colorectal cancer 11
type 1 diabetes 11
squamous cell carcinoma 11
myocardial infarction 10
cirrhosis 10
hypercholesterolemia 10
gastric cancer 10
lung carcinoma 10
dementia 9
HIV 9
tumorigenesis 9
renal disease 9
colon cancer 9
tumor progression 9
asthma 8
Down syndrome 8
diabetic nephropathy 8
acute myocardial infarction 8
iron overload 8
plaque 7
B-cell lymphoma 7
fatty liver 7
epilepsy 7
tardive dyskinesia 7
OPA1 7
glioblastoma 7
liver disease 6
hyperlipidemia 6
FAS 6
coronary artery disease 6
Chagas 6
parkinsonism 6
mitochondrial disease 6
Copper deficiency 6
pheochromocytoma 6
subarachnoid hemorrhage 6
Diaphragm 6
chronic disease 5
bladder cancer 5
schizophrenia 5
muscular atrophy 5
heart disease 5
Graves' disease 5
vascular disease 5
metabolic syndrome 5
liver cancer 5
adenoma 5
respiratory failure 5
bacterial infection 5
dyslipidemia 5
inflammatory bowel disease 5
bronchopulmonary dysplasia 5
colitis 5
fibrosarcoma 5
HSP 4
congestive heart failure 4
Mycobacterium 4
IVF 4
proteinuria 4
Evans 4
virus infection 4
cerebral infarction 4
ATM 4
neoplastic transformation 4
ovarian cancer 4
brain edema 4
cornea 4
pneumonia 4
insulinoma 4
infectious diseases 4
uterus 4
Blocking 4
Endothelial dysfunction 4
liver fibrosis 4
Leigh syndrome 4
Barrett's esophagus 4
renal cancer 4
osteoporosis 4
coronary occlusion 4
hepatitis C 4
chronic hepatitis 4
endotoxic shock 4
chronic obstructive pulmonary disease 4
premature aging 4
hepatitis B 4
pulmonary fibrosis 3
TTP 3
diabetic cardiomyopathy 3
acute pancreatitis 3
worms 3
fungal infection 3
DBA 3
muscular dystrophy 3
psoriasis 3
TTP 3
aspergillosis 3
lactic acidosis 3
cystitis 3
hyperinsulinemia 3
polyneuropathy 3
Bladder 3
tuberculosis 3
dehydration 3
Crohn's disease 3
Huntington's disease 3
Bladder 3
neuronal ceroid lipofuscinosis 3
mole 3
obstructive sleep apnea 3
hyaline membrane disease 3
mole 3
MIP 3
hypertrophic cardiomyopathy 3
aggressiveness 3
memory impairment 3
autism 3
encephalopathy 3
autoimmune disease 3
TEM 3
more...
Symptom
hyperoxia 49
starvation 14
seizures 11
fatigue 10
anesthesia 6
collapse 6
exhaustion 6
pain 5
ophthalmoplegia 5
ataxia 5
angina 4
acidity 4
acute stress 4
weakness 3
tremor 3
hypothermia 3
functional recovery 3
chills 2
cachexia 2
cerebellar ataxia 1
tonic-clonic seizure 1
muscle rigidity 1
constipation 1
Decreased activity 1
respiratory distress 1
Catch 1
dyspnea 1
Mills 1
dystonia 1
cancer pain 1
menopausal symptoms 1
Diaphragmatic weakness 1
bradykinesia 1
spasm 1
Drug
ROS 153
ascorbate 63
vitamin E 37
lysine 23
NADH 18
Glutathione 14
Vitamin E 12
MAP 12
Dermatol 11
Parkin 8
Parkin 8
Indomethacin 7
Ethanol 7
Capsicum 7
Cardiovasc 6
Adriamycin 6
nitroglycerin 5
Nephron 5
IL-2 5
Gel 5
Heme 4
Nitric Oxide 4
CSF 3
Asn 3
lactose 3
Vitamin A 3
TTC 3
Leaf 3
FLP 3
Nephron 3
Vitamin K 2
Asthma 2
Desferal 2
Alanine 2
EE2 2
Photofrin 2
IFN-gamma 2
Desferal 2
PCB 2
Nimesulide 2
Ciprofibrate 2
ALA 2
caffeine 2
G418 2
ABC 2
CoCl2 2
CoCl2 2
Pilocarpine 2
ETS 1
Levosimendan 1
Allergen 1
ZnCl2 1
SiO2 1
Pyridostigmine bromide 1
2-Methoxyestradiol 1
CTC 1
NBT 1
Frontal 1
Captopril 1
linolenate 1
Salicylate 1
Ranolazine 1
ZnCl2 1
Bezafibrate 1
Ketoconazole 1
Pyridostigmine bromide 1
Tirapazamine 1
Fluorescein 1
Sorafenib 1
Molsidomine 1
SMP 1
Beraprost sodium 1
beta-Galactosidase 1
ETA 1
Monit 1
Rosiglitazone 1
Bifidobacterium 1
Triclosan 1
DNase I 1
DMI 1
ZnO 1
CPR 1
Tacrolimus 1
Dithranol 1
Aloe 1
FAD 1
Gefitinib 1
Rosuvastatin 1
Fructose 1
ADR 1
4-Hydroxytamoxifen 1
Phosphatidylserine 1
Tenidap 1
Riboflavin 1
NOV 1
Lovastatin 1
CTC 1
AMC 1
Doxycycline 1
TAC 1
ICI 1
Tocopherol 1
Epigallocatechin 1
Arsenic trioxide 1
TAT 1
Mutagen 1
p75 1
Bosentan 1
Glucantime 1
Coral 1
DHT 1
Finasteride 1
Emodin 1
Emodin 1
Camp 1
Acacia 1
Cetuximab 1
DHT 1
Troglitazone 1
Lactose 1
Bosentan 1
Ranolazine 1
Diurnal 1
Pramlintide 1
Estrogens 1
Ulinastatin 1
MRC 1
niacin 1
TiO2 1
Enzyme
superoxide dismutase 1743
catalase 832
glutathione peroxidase 423
glutathione reductase 154
peroxidase 87
mitogen-activated protein kinase 82
caspase-3 79
glutathione S-transferase 76
NADPH oxidase 65
complex I 53
NADPH oxidase 50
xanthine oxidase 49
ascorbate peroxidase 42
ERK 36
NO synthase 32
aconitase 31
alanine aminotransferase 30
NQO1 28
AMP-activated protein kinase 27
PARP 24
protein kinase 24
citrate synthase 23
cytochrome oxidase 22
protein kinase C 22
glucose-6-phosphate dehydrogenase 22
lactate dehydrogenase 22
caspase-9 21
NOS 19
peroxiredoxin 19
ATPase 19
succinate dehydrogenase 19
AMPK 19
AMPK 19
aspartate aminotransferase 19
heme oxygenase 18
reverse transcriptase 16
lysozyme 15
ATP synthase 14
creatine kinase 14
luciferase 13
gamma-glutamylcysteine synthetase 11
diaphorase 11
isocitrate dehydrogenase 10
alkaline phosphatase 10
MEK 10
dehydroascorbate reductase 10
focal adhesion kinase 10
SOR 9
ceruloplasmin 9
CPR 9
tyrosine hydroxylase 9
caspase-8 9
AST 9
PKG 8
MAP 8
acetylcholinesterase 8
glyceraldehyde-3-phosphate dehydrogenase 8
phospholipid hydroperoxide glutathione peroxidase 8
acid phosphatase 8
glutamine synthetase 8
thioredoxin reductase 8
isocitrate dehydrogenase 7
malate dehydrogenase 7
beta-galactosidase 7
monoamine oxidase 7
DCF 6
lipoxygenase 6
IKK 6
arginase 6
trypsin 6
NADH dehydrogenase 6
glyceraldehyde-3-phosphate dehydrogenase 6
aldehyde dehydrogenase 5
ACE 5
gamma-glutamyl transpeptidase 5
RNA polymerase 5
proteasome 5
glyceraldehyde-3-phosphate dehydrogenase 5
TOR 5
aldose reductase 5
aldehyde dehydrogenase 4
aldehyde dehydrogenase 4
MPP 4
aldehyde dehydrogenase 4
GSK 4
aldehyde dehydrogenase 4
glutathione synthetase 4
renin 4
calcineurin 4
enolase 4
cholinesterase 4
DNA ligase 3
DNA ligase 3
MIP 3
nitrogenase 3
phospholipase A2 3
lipoprotein lipase 3
TdT 3
phosphatidylinositol 3-kinase 3
caspase-1 3
PDK1 3
transcriptase 3
glyceraldehyde-3-phosphate dehydrogenase 3
AMP-activated kinase 3
cathepsin D 3
chaperonin 3
ACS 3
choline acetyltransferase 3
coproporphyrinogen oxidase 3
guanylate cyclase 3
histone acetyltransferase 3
myosin light chain kinase 3
cysteine synthase 3
glyceraldehyde-3-phosphate dehydrogenase 3
HPI 3
glucose oxidase 2
acyl-CoA dehydrogenase 2
soluble epoxide hydrolase 2
nitrate reductase 2
glutamate dehydrogenase 2
peptidyl-prolyl cis-trans isomerase 2
glutamate dehydrogenase 2
glutamate dehydrogenase 2
collagenase 2
lipase 2
MMP 2
xanthine dehydrogenase 2
nitrate reductase 2
farnesyltransferase 2
nitrate reductase 2
oxalate oxidase 2
proteinase K 2
nitrate reductase 2
nitrate reductase 2
chymotrypsin 2
transglutaminase 2
nitrate reductase 2
ALDH 2
pyruvate kinase 2
phosphoglycerate kinase 2
thymidine kinase 2
pyruvate dehydrogenase 2
arginine kinase 2
ferrochelatase 2
acyl-CoA oxidase 2
phospholipase C 2
ECH 2
caspase-7 2
farnesyltransferase 2
fumarase 2
LPL 2
CPS 2
pyruvate carboxylase 2
acetyl-CoA carboxylase 2
alpha-glucosidase 2
caspase-7 2
aldolase 2
coproporphyrinogen III oxidase 2
orotate phosphoribosyltransferase 1
topoisomerase 1
more...
Compound
oxygen 811
manganese 306
DNA 304
GSH 267
GSH 267
hydrogen 217
Dec 216
copper 206
zinc 166
H2O2 162
superoxide radical 148
nitric oxide 135
CAT 134
CAT 134
CAT 134
iron 122
water 121
glucose 110
TNF 81
MDA 75
ATP 68
GSSG 65
Clin 49
sodium 49
nitrogen 49
calcium 46
salt 46
cysteine 44
ethanol 42
N-acetylcysteine 41
cadmium 37
alanine 37
tyrosine 37
cyanide 32
phosphate 31
selenium 31
NADPH 30
NADPH 30
lysine 27
8-OHdG 27
arginine 26
PEG 25
acetate 25
sulfate 23
ADP 22
ammonium 22
ADP 22
ADP 22
His 21
proline 20
NAD 20
glutamate 20
NADH 18
methionine 18
potassium 17
SDS 17
NAD 16
nicotinamide 16
galactose 16
PEG 16
MTT 15
serine 15
Resveratrol 15
nitrate 15
glutamine 14
Adriamycin 14
Panam 13
urea 13
Vitamin E 13
Melatonin 13
Ascorbic acid 13
Insulin 12
MAP 11
2-nonenal 11
nickel 11
creatinine 11
threonine 11
cGMP 11
Asp 10
HCl 10
diacetate 10
hydroxide 10
NH2 10
leucine 10
CO2 10
TOF 9
tryptophan 9
iodine 9
ADR 9
tryptophan 9
EDTA 9
MPTP 9
EDTA 9
NADP 9
tryptophan 9
tryptophan 9
dUTP 8
Cardiol 8
Paraquat 8
Paraquat 8
ammonia 8
tert-butyl hydroperoxide 8
Cu(II) 8
bromide 8
DBA 7
pyrene 7
acrylamide 7
STZ 7
cAMP 7
aldehyde 7
aldehyde 7
mercury 7
salicylic acid 7
MEK 7
Thiobarbituric acid 6
naphthoquinone 6
DMSO 6
chloroform 6
naphthoquinone 6
cobalt 6
coenzyme Q10 6
naphthoquinone 6
AMP 6
aluminum 6
naphthoquinone 6
DPPH 6
silver 6
anthracene 6
Quercetin 6
benzoic acid 6
naphthoquinone 6
COX 6
naphthoquinone 6
fluorine 6
Phe 6
TCA 6
naphthoquinone 6
guanidine 5
APAP 5
8-hydroxyguanosine 5
Hearts 5
methanol 5
chromium 5
DETA 5
ALP 5
Malondialdehyde 5
TEM 5
Estrogen 5
Tempol 5
Estrogen 5
valine 5
hydroquinone 5
ASA 5
PMA 5
retinoic acid 5
BSO 5
CdCl2 5
Cytochrome c 5
Off 5
aspartic acid 4
more...