Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P04141 (
granulocyte-macrophage colony-stimulating factor
)
6,790
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We present the case of a 43-year-old woman with a diagnosis of pulmonary alveolar proteinosis, on chronic treatment with
sargramostim
, a recombinant
granulocyte-macrophage colony-stimulating factor
, who presented with the nephrotic syndrome secondary to biopsy-proven
membranous nephropathy
. We discuss potential underlying mechanisms, including speculated effects of
sargramostim
on mesangial cells and the kidney resident macrophages, and review the existing literature on the potential association between these two disorders.
...
PMID:Potential association between membranous nephropathy and sargramostim therapy for pulmonary alveolar proteinosis. 2904 31
