Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P04040 (Catalase)
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Human Gene/Protein
Catalase 3577
catalase 1702
superoxide dismutase 962
glutathione peroxidase 415
GSH 310
peroxidase 293
Superoxide dismutase 281
Sep 243
antioxidant enzyme 221
SOD 212
glutathione reductase 209
Mol 198
xanthine oxidase 141
Glutathione peroxidase 100
NADH 91
NADPH 89
glutathione S-transferase 86
CAT 86
nov 74
ROS 70
caspase-3 64
lactate dehydrogenase 63
MnSOD 61
insulin 57
microsomal 52
ATP 49
reductase 46
myeloperoxidase 46
acetylcholinesterase 45
p53 44
cytochrome c 44
TNF 42
hemoglobin 41
GST 36
Bcl-2 34
nitric oxide synthase 34
Pseudomonas 33
alkaline phosphatase 33
cytokine 32
endoplasmic reticulum 32
albumin 30
glucose-6-phosphate dehydrogenase 30
SDS 29
EPR 29
collagen 29
IL-6 29
aspartate aminotransferase 28
ATPase 28
phosphatase 27
spermatozoa 27
p38 27
ESR 26
lipopolysaccharide 26
NAD 25
inducible nitric oxide synthase 25
polypeptide 25
cytochrome 25
Glutathione S-transferase 25
Nrf2 23
tumor necrosis factor 23
ADP 23
oxidoreductase 22
MAPK 22
Gen 21
serum albumin 21
casein 20
thioredoxin 20
SOD1 20
ferritin 19
membrane-bound 19
LDH 19
manganese superoxide dismutase 19
cyclooxygenase 18
acyl-CoA oxidase 18
JNK 18
cytochrome P-450 18
LPO 18
metallothionein 18
D-amino acid oxidase 17
AST 17
glutathione peroxidase 1 17
lipoxygenase 17
gut 16
glutathione transferase 16
acid phosphatase 16
c-Ha-ras 15
Met 14
COX-2 14
HSP70 14
malate dehydrogenase 14
Myeloperoxidase 14
alanine aminotransferase 14
ERK 14
guanylate cyclase 13
PEG 13
ERK1 13
cytochrome P450 12
carp 12
angiotensin II 12
interferon 12
SOD2 12
HO-1 12
DT-diaphorase 12
NMR 11
HPI 11
eNOS 11
myoglobin 11
methemoglobin 11
C18 11
CA1 10
P450 10
SIN 10
esterase 10
thymus 10
heme oxygenase-1 10
Pol 10
APE1 10
creatine kinase 10
interleukin-6 10
ubiquinone 10
kit 10
LPS 9
TOF 9
CAT1 9
STZ 9
GSR 9
xenobiotic 9
Metallothionein 9
heat shock protein 9
Cytochrome c 9
p65 9
CO2 9
aldehyde dehydrogenase 9
superoxide dismutase 1 9
glycolate oxidase 9
AChE 9
tumor necrosis factor alpha 9
lactoperoxidase 9
annexin V 9
diaphorase 8
C15 8
HPII 8
alcohol dehydrogenase 8
caspase-9 8
NAD+ 8
amine oxidase 8
HDL 8
NADP 8
ferredoxin 8
vascular endothelium 8
erythroid 8
amylase 8
ceruloplasmin 8
IFN 8
epididymal 8
Cu/Zn superoxide dismutase 8
CAT-3 8
isocitrate dehydrogenase 7
ANOVA 7
transferrin 7
more...
Disease
GSH 310
cancer 119
tumor 85
ischemia 76
diabetes 75
carcinogenesis 54
cold 31
Mycobacterium 29
SDS 29
hepatocellular carcinoma 24
Alzheimer's disease 22
hypertension 21
stroke 21
Parkinson's disease 20
depression 20
NAME 19
tuberculosis 19
leukemia 19
carcinoma 18
atherosclerosis 17
hyperglycemia 16
obesity 14
sepsis 13
myocardial ischemia 13
breast cancer 13
SEM 13
sepsis 13
melanoma 12
Zellweger syndrome 11
pheochromocytoma 10
asthma 10
MCF 10
chronic granulomatous disease 10
plaque 10
epididymis 9
worms 8
rheumatoid arthritis 8
cataract 8
preeclampsia 8
renal disease 8
cerebral ischemia 8
lymphoma 8
arthritis 7
type 1 diabetes 7
heart failure 7
dementia 7
cardiovascular disease 7
cognitive impairment 7
PCC 7
myocardial infarction 7
colon cancer 7
type 2 diabetes 7
neuroblastoma 7
lung cancer 7
colitis 7
prostate cancer 6
Evans 6
inflammatory bowel disease 6
pulmonary edema 6
tumorigenesis 6
adenocarcinoma 6
iron overload 6
vitiligo 6
Proteus 6
diabetic cardiomyopathy 6
Haemophilus 6
ash 6
anemia 6
colorectal cancer 5
multiple myeloma 5
Klebsiella 5
squamous cell carcinoma 5
hyperlipidemia 5
hypercholesterolemia 5
HIV 5
malaria 5
TEM 5
liver disease 5
cornea 5
gastric cancer 5
chronic renal failure 5
acute promyelocytic leukemia 5
hepatitis 5
TEM 4
male infertility 4
ICP 4
proteinuria 4
cholera 4
immunodeficiency 4
bladder cancer 4
gonococcal 4
cirrhosis 4
virus infection 4
osteoarthritis 4
hypothyroidism 4
renal ischemia 4
leprosy 4
neuropathy 4
vagina 4
thalassemia 4
uterus 4
cystic fibrosis 4
cardiomyopathy 4
ALD 4
dehydration 4
acute renal failure 4
chronic myeloid leukemia 4
renal failure 4
systemic lupus erythematosus 4
tumor progression 4
IBR 4
chronic obstructive pulmonary disease 4
metabolic disorder 4
WT1 4
Refsum disease 4
tumor growth 4
Brown 3
Helicobacter pylori infection 3
Down syndrome 3
Testis 3
cholestasis 3
Takahara 3
FBS 3
Disorder 3
Epstein 3
heart disease 3
BDE 3
B-cell lymphoma 3
diabetic nephropathy 3
Chlamydia 3
aggression 3
PHA 3
otitis media 3
amyotrophic lateral sclerosis 3
fatty liver 3
emphysema 3
vitamin A deficiency 3
status epilepticus 3
meningitis 3
glioma 3
acute pancreatitis 3
memory impairment 3
Testis 3
pulmonary hypertension 3
hyperthyroidism 3
epilepsy 3
gastritis 3
metabolic syndrome 3
gastroenteritis 3
PCA 3
liver fibrosis 3
mole 3
mole 3
coronary artery disease 3
conjunctivitis 3
Schistosoma mansoni 3
metastases 3
mastitis 3
gastric ulcer 3
Tumour necrosis 2
more...
Symptom
hyperoxia 22
starvation 17
tremor 8
collapse 8
seizures 8
fatigue 6
pain 6
diarrhea 5
hypotonia 4
anesthesia 4
hypercapnia 4
acidity 3
functional recovery 3
chills 3
hepatomegaly 3
exhaustion 3
agitation 2
thinning 2
stigma 2
respiratory distress 2
Neuropathic pain 1
hangover 1
ACHE 1
emaciation 1
nausea 1
angina 1
lethargy 1
Catch 1
Ill 1
acute stress 1
overweight 1
insomnia 1
weakness 1
Spots 1
ENT 1
HSA 1
DNA marker 1
Decreased activity 1
chorea 1
skin damage 1
memory loss 1
arthralgia 1
incoordination 1
hypoproteinemia 1
Drug
ascorbate 140
Glutathione 140
NADH 91
ROS 70
vitamin E 61
Indomethacin 20
Vitamin E 14
Cardiovasc 14
Dermatol 13
lysine 11
Ethanol 11
Leaf 10
Asn 9
Nitric Oxide 9
Desferal 9
Desferal 9
lactose 9
ZnO 8
Monit 8
Heme 8
ALA 8
Vitamin K 7
Gel 7
CSF 6
MAP 5
Mutagen 5
Captopril 5
Arsenic trioxide 5
Alanine 4
Clofibrate 4
IFN-gamma 4
FeCl3 4
caffeine 4
Adenosine deaminase 4
NBT 4
Honey 4
Gelatin 4
Adriamycin 4
Simvastatin 3
pyridoxal phosphate 3
Ouabain 3
Albumin 3
Fluorescein 3
ampicillin 3
CTX 3
Rasburicase 3
FAD 3
citric acid 3
EE2 3
Deuterium oxide 3
Myricetin 3
balanced salt solution 3
TiO2 3
Kenyan 3
nitroglycerin 3
Malonaldehyde 3
IFN-beta 3
Fructose 2
IL-2 2
TAC 2
Angiotensin II 2
Acacia 2
Silica 2
MEA 2
Bifidobacterium 2
Metrizamide 2
Asthma 2
ZnCl2 2
Rutin 2
Histamine 2
L-tyrosine 2
AZT 2
ADR 2
Nephron 2
CoCl2 2
ZnCl2 2
ETA 2
CoCl2 2
CAM 2
AZT 2
Fluorescein 2
Apomorphine 1
TTC 1
Dithranol 1
Atrovent 1
Ferrous sulfate 1
Vitamin B 1
CTX 1
Cimetidine 1
Gluthathione 1
Spectrum 1
Estrogens 1
Wine 1
CaCl2 1
CaCl2 1
Vitamin B12 1
Carbidopa 1
Phosphatidylserine 1
PCB 1
Ciprofibrate 1
Epigallocatechin 1
Cimetidine 1
Cellulase 1
Iloprost 1
Lead acetate 1
Idarubicin 1
Glycerol 1
1,2,4-Triazole 1
Isoniazid 1
NAG 1
Luteinizing 1
Glucose-6-Phosphate 1
Salicylic Acid 1
Donepezil 1
Ranitidine 1
PPA 1
Emodin 1
Kainic acid 1
EPA 1
niacin 1
VCR 1
Adenosine triphosphate 1
FLP 1
THF 1
NAH 1
Aloe 1
Sodium hypochlorite 1
NH3 1
Pyridostigmine bromide 1
VCR 1
ETS 1
Isoxsuprine hydrochloride 1
BH4 1
Orgotein 1
Areca 1
Rhamnose 1
linolenate 1
Spectrum 1
Brij 30 1
MIL 1
Soybean oil 1
Methylene blue 1
Riboflavin 1
Peracetic acid 1
Vorinostat 1
Cobalamin 1
CTX 1
9-THC 1
Adenosine Monophosphate 1
Sodium nitroprusside 1
CaCl2 1
CrCl3 1
Methylprednisolone 1
Pyridostigmine bromide 1
SMP 1
Lipoic Acid 1
OTC 1
Fipronil 1
ENT 1
Photofrin 1
more...
Enzyme
catalase 1775
superoxide dismutase 1119
glutathione peroxidase 426
peroxidase 364
glutathione reductase 188
xanthine oxidase 135
glutathione S-transferase 130
lactate dehydrogenase 66
mitogen-activated protein kinase 57
ascorbate peroxidase 55
aspartate aminotransferase 46
glucose oxidase 43
alanine aminotransferase 43
caspase-3 42
acetylcholinesterase 39
NADPH oxidase 38
glucose-6-phosphate dehydrogenase 35
alkaline phosphatase 33
NADPH oxidase 33
urease 33
urease 33
ATPase 30
NQO1 27
uricase 26
diaphorase 26
acyl-CoA oxidase 24
tyrosinase 22
succinate dehydrogenase 20
protein kinase 20
CPR 18
cytochrome oxidase 18
acid phosphatase 17
AST 17
ERK 17
lipoxygenase 17
monoamine oxidase 16
glycolate oxidase 14
complex I 14
guanylate cyclase 14
NO synthase 14
malate dehydrogenase 14
nitrate reductase 13
nitrate reductase 13
nitrate reductase 13
nitrate reductase 13
nitrate reductase 13
cholinesterase 13
nitrate reductase 13
creatine kinase 12
invertase 12
luciferase 12
protein kinase C 12
trypsin 12
delta-aminolevulinic acid dehydratase 11
gamma-glutamyl transpeptidase 11
peroxiredoxin 10
diamine oxidase 10
ceruloplasmin 10
MEK 10
aldehyde dehydrogenase 10
aldehyde dehydrogenase 10
NADPH-diaphorase 9
aldehyde dehydrogenase 9
SOR 9
alcohol dehydrogenase 9
cytochrome c peroxidase 9
dehydroascorbate reductase 9
aldehyde dehydrogenase 9
AMP-activated protein kinase 9
aldehyde dehydrogenase 9
diaphorase 9
glyceraldehyde-3-phosphate dehydrogenase 8
HPI 8
beta-galactosidase 8
chymotrypsin 7
isocitrate dehydrogenase 7
PAH 7
ACE 7
isocitrate dehydrogenase 7
phospholipase A2 7
elastase 7
lysozyme 7
NOS 7
thrombin 7
DCF 7
citrate synthase 7
glyceraldehyde-3-phosphate dehydrogenase 7
glyceraldehyde-3-phosphate dehydrogenase 6
Fpg protein 6
phenol oxidase 6
glutamate dehydrogenase 6
hydroxypyruvate reductase 6
focal adhesion kinase 6
malate synthase 6
caspase-9 6
isocitrate lyase 6
hydroxypyruvate reductase 6
ECH 6
reverse transcriptase 6
heme oxygenase 6
glutamate dehydrogenase 6
glutamate dehydrogenase 6
NADH dehydrogenase 5
alcohol oxidase 5
beta-glucuronidase 5
PARP 5
topoisomerase 5
phosphoenolpyruvate carboxykinase 5
topoisomerase 5
phosphatidylinositol 3-kinase 5
glutamine synthetase 5
sucrase 5
glyceraldehyde-3-phosphate dehydrogenase 5
5'-nucleotidase 5
pyruvate oxidase 5
gamma-glutamylcysteine synthetase 5
papain 5
NADH peroxidase 5
pyruvate oxidase 5
glyceraldehyde-3-phosphate dehydrogenase 5
deaminase 4
ACS 4
phospholipid hydroperoxide glutathione peroxidase 4
phospholipase C 4
laccase 4
lipase 4
fumarase 4
phenylalanine hydroxylase 4
aconitase 4
thioredoxin reductase 4
ATP synthase 4
PAL 4
proteasome 4
xanthine dehydrogenase 4
cathepsin D 4
KAT 4
arginase 4
ALDH 4
phosphodiesterase 3
formate dehydrogenase 3
RNase 3
3-hydroxyacyl-CoA dehydrogenase 3
carbonic anhydrase 3
cellulase 3
hexokinase 3
phosphoenolpyruvate carboxykinase 3
6-phosphogluconate dehydrogenase 3
sulfiredoxin 3
paraoxonase 3
phosphoenolpyruvate carboxylase 3
alpha-ketoglutarate dehydrogenase 3
collagenase 3
tyrosine hydroxylase 3
phosphoenolpyruvate carboxykinase 3
alpha-glucosidase 3
AMPK 3
polyamine oxidase 3
ornithine decarboxylase 3
caspase-8 3
AMPK 3
more...
Compound
oxygen 979
hydrogen 778
H2O2 667
GSH 413
GSH 413
DNA 384
water 286
Dec 274
iron 194
glucose 186
sodium 180
copper 179
ethanol 122
nitric oxide 120
superoxide radical 118
Clin 103
acetate 101
NADH 91
NADPH 89
cysteine 89
NADPH 89
CAT 86
CAT 86
CAT 86
nitrogen 85
phosphate 82
calcium 79
Ascorbic acid 76
Malondialdehyde 76
zinc 74
arginine 68
manganese 68
tyrosine 65
cyanide 65
His 64
EDTA 63
EDTA 61
sulfate 60
MDA 59
Cu(II) 56
GSSG 56
nitrate 55
salt 55
cadmium 52
urea 51
methionine 51
selenium 49
ATP 49
N-acetylcysteine 42
TNF 42
potassium 42
methanol 38
creatinine 36
ammonium 35
DMSO 32
thiourea 32
SDS 31
NAD 30
aldehyde 29
proline 27
alanine 27
galactose 26
diacetate 26
ADP 25
NAD 25
PEG 25
glycerol 25
hydroquinone 24
ADP 23
phenol 23
ADP 23
tryptophan 22
tryptophan 22
tryptophan 22
CO2 22
tryptophan 22
acetaldehyde 21
iodine 21
DFO 21
glutamate 21
DSM 21
mercury 20
Phe 20
acetic acid 20
chromium 19
PEG 19
MTT 18
CoA 18
8-OHdG 18
hydroxide 17
Vitamin E 17
pyrene 17
hydroxylamine 17
bromide 17
L-DOPA 16
pyridine 16
hydroxylamine 16
salicylic acid 15
ammonia 15
silver 15
Cardiol 15
alloxan 15
formaldehyde 14
Thiobarbituric acid 14
piperidine 14
formaldehyde 14
acrylamide 14
Indomethacin 14
Menadione 14
piperidine 14
Triton X-100 13
serine 13
STZ 13
Lactate 12
Mannitol 12
ubiquinone 12
cobalt 12
DEAE 12
ACh 12
leucine 12
NADP 12
ATA 11
Mannitol 11
nicotinamide 11
chromate 11
Asp 11
Mg2+ 10
Lead 10
Dexamethasone 10
Tris 10
vanadium 10
prostacyclin 10
cGMP 10
aldehyde 10
formic acid 10
nickel 10
NH2 10
Tris 10
xylose 10
Heme 9
lysine 9
Desferal 9
alcohol dehydrogenase 9
Insulin 9
Adriamycin 9
DPPH 9
ABA 9
TOF 9
retinol 9
DTPA 9
gallic acid 9
Cysteine 9
Gly 9
pentose 9
ClO 9
Cytochrome c 9
Tempol 8
pentose 8
hexose 8
ABA 8
more...