Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P02794 (ferritin)
17,525 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Septicemia of Vibrio spp. such as non-O1 Vibrio cholerae presented with diarrhea, fasciitis, cellulitis or otitis media are common in cirrhotic patients (Lin, C.-J., Chiu, C.-T., Lin, D.-Y., et al., Am. J. Gastroenterol., 91, 336-340, 1996). It may result from a lower C3/C4 level, a lower serum ferritin level or opsonophagocytosis dysfunction. High mortality in such cases has been noted. However, endophthalmitis is rare in such patients, and has never been reported. We present a cirrhotic patient of non-O1 and non-O139 V. cholerae septicemia complicated with endophthalmitis.
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PMID:A case of non-O1 and non-O139 Vibrio cholerae septicemia with endophthalmitis in a cirrhotic patient. 1905 Mar 58

Gram-positive Streptococcus species are responsible for millions of cases of meningitis, bacterial pneumonia, endocarditis, erysipelas and necrotizing fasciitis. Iron is essential for the growth and survival of Streptococcus in the host environment. Streptococcus species have developed various mechanisms to uptake iron from an environment with limited available iron. Streptococcus can directly extract iron from host iron-containing proteins such as ferritin, transferrin, lactoferrin and hemoproteins, or indirectly by relying on the employment of specialized secreted hemophores (heme chelators) and small siderophore molecules (high affinity ferric chelators). This review presents the most recent discoveries in the iron acquisition system of Streptococcus species - the transporters as well as the regulators.
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PMID:Iron acquisition and regulation systems in Streptococcus species. 2466 93