Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P02774 (
Gc-globulin
)
196
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The binding properties towards vitamin D metabolites of plasma from individuals with the three common
Gc-globulin
phenotypes, Gc-1, Gc-2 and Gc-2-1, have been found to be identical. In patients with liver disease there is a good correlation between the levels of
Gc-globulin
andalbumin in plasma. In addition the
Gc-globulin
levels correlate well with the ability of plasma to bind 25-hydroxycholecalciferol. Patients with the Gc-2-1 phenotype showed a significantly smaller
depression
in plasma
Gc-globulin
than those with the Gc-2 and Gc-1 phenotypes. The relation of these findings to the pathogenesis of disorders of calcium metabolism in liver disease is discussed.
...
PMID:Vitamin D binding globulin phenotypes in liver disease. 9 74
