Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P01889 (ankylosing spondylitis)
 5,717 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
PADI 1 12.4
Major histocompatibility complex, class I, B 12.4
transmembrane and tetratricopeptide repeat containing 1 12.4
phospholipase D family, member 4 12.4
ankylosing spondylitis 12.4
MRPL22 12.4
HLA-B*2712 12.4
ankyrin repeat domain 38 12.4
TTC38 12.4
B*2706 11.4
MRPL25 11.4
HLA-B27 mRNA 11.4
Peptidyl arginine deiminase, type IV 11.4
HLA-B27 10.9
Leukocyte immunoglobulin-like receptor A3 10.9
G6E 10.9
mitochondrial ribosomal protein S11 10.9
SAP30BP 10.9
craniofacial development protein 1 10.9
endoplasmic reticulum aminopeptidase 2 10.7
HLA-B*27 10.7
B27 10.6
HLA-B27 protein 10.6
RBP5 10.4
HLA-Bw62 antigen 10.4
interleukin 17 receptor C 10.4
prefoldin subunit 5 10.4
sterile alpha motif domain containing 9 10.4
peptidyl arginine deiminase type IV 10.1
HLA class I alpha chain 10.1
TST2 10.1
ERAP1 10.1
Endoplasmic reticulum aminopeptidase 1 10.0
Interleukin 23 receptor 9.9
Fc receptor-like 5 9.9
HLA B 9.8
BAT5 9.6
leucocyte immunoglobulin-like receptor 9.6
KIF21B 9.6
BRWD1 9.4
HSP70-Hom 9.4
G6C 9.3
Phospholipase D4 9.3
integral membrane protein 2A 9.1
B4GALT3 9.1
LECT1 9.1
IL23R 9.1
ERAP2 9.1
PIP4K2C 9.0
IP6K3 9.0
protein tyrosine phosphatase receptor type C 9.0
PSMG1 9.0
CREG 8.9
killer-cell Ig-like receptor 8.9
SINTBAD 8.6
KLRC4 8.6
ANTXR2 8.5
HLA-B39 8.5
ANKH 8.5
MICA protein 8.4
human leukocyte antigen B 8.4
FCRL5 8.4
HLA-E protein 8.4
B144 8.4
KIR3DS1 8.4
p75 TNF receptor 8.4
TMEM45A 8.4
KIR2DL5A 8.3
ribosomal protein L17 8.3
G6D 8.3
Cw*08 8.3
JARID1A 8.3
OPLL 8.2
B60 8.2
DEFA3 8.2
GNG11 8.2
Chloride intracellular channel protein 1 8.2
HAPLN1 8.2
LILRA3 8.2
histocompatibility antigen 8.2
more...
Disease
Reactive arthropathy 12.4
Necrotizing esophagitis 12.4
Juvenile spondyloarthropathy 12.4
Follicular occlusion triad 12.4
ankylosing spondylitis 12.3
Romanus lesion 11.7
Acute uveitis 11.4
Acute anterior uveitis 11.4
Juvenile ankylosing spondylitis 11.2
sacroilitis 11.1
Vertebral osteoporosis 11.1
HLA-B27 10.9
yersinia enteritis 10.9
Seronegative arthritis 10.9
Skin deposits 10.9
sacroiliitis 10.8
MS-like syndrome 10.6
Spondyloarthritis 10.5
Esophageal infections 10.4
Reiter's syndrome 10.3
enthesitis 10.3
Seropositive rheumatoid arthritis 10.3
spondyloarthropathy 10.3
psoriatic arthritis 10.2
Enteropathic arthritis 10.1
Osteitis condensans ilii 9.9
Secondary osteoarthritis 9.9
enthesopathy 9.7
Gastrointestinal amyloidosis 9.6
Lupus-like syndrome 9.6
spondylitis 9.6
Juvenile psoriatic arthritis 9.4
Intervertebral disc calcification 9.4
anterior uveitis 9.3
Bony ankylosis 9.3
Plasma cell infiltration 9.3
Alkaptonuric ochronosis 9.3
dactylitis 9.2
panmyelophthisis 9.1
digestive infection 9.1
Protrusio acetabuli 9.1
Gastrointestinal inflammation 9.0
Launois 9.0
Ochronotic arthropathy 8.9
cauda equina syndrome 8.9
Reactive arthritis 8.9
Posterior synechiae 8.9
Band keratopathy 8.9
cervical spine syndrome 8.9
Diffuse idiopathic skeletal hyperostosis 8.8
Posterior uveitis 8.8
Inflammatory disease 8.7
Posner-Schlossman syndrome 8.7
Necrotizing scleritis 8.6
Phlyctenular keratoconjunctivitis 8.6
Erythrodermic psoriasis 8.5
PUVA lentigines 8.5
Non-secretory myeloma 8.5
Idiopathic hypoparathyroidism 8.5
coxitis 8.5
iritis 8.5
Spinal epidural hematoma 8.4
Cauda equina 8.4
hyperostosis 8.4
renal scleroderma 8.4
cervical disc degeneration 8.3
juvenile rheumatoid arthritis 8.2
OPLL 8.2
Chronic periaortitis 8.2
Erosive osteoarthritis 8.2
Bronchocentric granulomatosis 8.1
familial hypophosphatemia 8.1
polyarthrosis 8.1
Mild depression 8.0
migratory arthritis 8.0
spondylopathy 7.9
Bone marrow edema 7.9
iridocyclitis 7.9
cervical arthritis 7.7
Pulmonary vasculitis 7.7
more...
Symptom
Ochronotic pigmentation 12.4
Sacroiliac joint laxity 12.4
Intermittent fever 8.7
rib pain 8.0
vaginal discomfort 8.0
pain in the buttock 7.7
polymyalgia 7.6
heel pain 7.5
Hyperextension 7.1
Cardiovascular symptoms 7.1
Radicular pain 7.0
chronic back pain 7.0
Livedoid 6.8
Musculoskeletal symptoms 6.7
postpartum pain 6.7
swollen joints 6.7
thoracic back pain 6.7
back pain 6.5
generalized pain 6.4
painful swallowing 6.4
low back pain 6.0
Overlying 6.0
lumbar instability 6.0
hip pain 5.7
cardiovascular impairment 5.7
neck pain 5.7
Poor sleep 5.5
sciatica 5.4
acute low back pain 5.3
dark urine 5.3
arthralgia 5.2
Severe pain 5.1
eye pain 4.9
pedal edema 4.7
clubbing 4.6
disturbed balance 4.6
aphonia 4.5
Stiffness 4.5
arm pain 4.5
groin pain 4.5
body pain 4.4
non-productive cough 4.3
urethral discharge 4.2
right lower quadrant pain 4.2
loin pain 4.1
Physical findings 4.1
thigh pain 4.1
shoulder pain 4.0
knee pain 4.0
loss of taste 3.9
paraparesis 3.8
night sweats 3.8
intestinal bleeding 3.8
livedo 3.7
acute pain 3.7
pain 3.6
Halo 3.6
motor symptom 3.6
dysesthesia 3.6
stomach pain 3.5
leg pain 3.4
dry eye 3.4
hyperesthesia 3.4
ankle pain 3.4
mental fatigue 3.3
Gastrointestinal symptoms 3.3
pleuritic chest pain 3.2
dental pain 3.2
neck stiffness 3.2
bone pain 3.2
rales 3.1
chronic constipation 3.1
numbness 3.1
asthenia 3.1
limb pain 3.1
paresthesia 3.0
fatigue 3.0
hemoptysis 2.9
renal colic 2.8
muscle cramps 2.6
more...
Drug
Golimumab 10.8
Feprazone 9.7
Alclofenac 9.7
Aristocort 9.6
Certolizumab pegol 9.2
Mobic 9.1
Adalimumab 9.1
Sulphasalazine 8.8
Tenoxicam 8.6
Infliximab 8.6
Infliximab 8.6
Aceclofenac 8.4
Pirprofen 8.4
Oxaprozin 8.1
Etodolac 8.1
Meclomen 7.9
Iguratimod 7.8
Fenoprofen 7.5
Isoxicam 7.5
Meclomen 7.4
Feldene 7.2
Fenbufen 6.9
Nabumetone 6.8
Lornoxicam 6.5
Adefovir dipivoxil 6.5
Arava 6.5
Tiaprofenic acid 6.5
Profenid 6.5
Abatacept 6.4
Anakinra 6.1
Diclofenac sodium 6.0
Anafranil 5.7
p75 5.6
Celebrex 5.5
Arthrex 5.5
Tuberculin 5.3
FLP 5.2
Auranofin 5.1
Salmon calcitonin 4.9
SPP 4.9
Novantrone 4.8
Rifaximin 4.7
IL-1ra 4.0
SBT 3.8
Rosuvastatin 3.6
THA 3.6
Moxifloxacin 3.6
Denosumab 3.3
Streptokinase 3.3
Rituximab 3.3
CED 3.3
RFP 3.2
Budesonide 3.1
Triad 3.0
Camp 2.9
Campath 2.9
Campath 2.9
CIA 2.8
CTX 2.8
CTX 2.8
Indomethacin 2.6
Methylprednisolone 2.6
Isoniazid 2.5
Omeprazole 2.5
Prednisone 2.5
EPI 2.4
BCG vaccine 2.3
AMC 2.2
Vitamin B12 2.2
ROC 2.1
Pronase 2.1
CTX 1.9
ABC 1.9
PTH 1.7
Diurnal 1.7
Check 1.5
NAG 1.4
Monit 1.3
CSF 1.2
Fluorescein 1.0
more...
Enzyme
galactosylhydroxylysyl glucosyltransferase 6.1
oxytocinase 5.6
aminopeptidase I 5.5
proteinase-3 5.0
homogentisate 1,2-dioxygenase 4.9
Lod 4.8
methionine synthase reductase 4.8
type III procollagen 4.6
nitrogenase 4.3
dimethylarginine dimethylaminohydrolase 4.2
peptidylarginine deiminase 4.0
pullulanase 3.9
chymopapain 3.8
chymopapain 3.7
factor D 3.6
MDP 3.6
prolidase 3.5
CDH 3.3
uricase 3.2
alanine aminopeptidase 2.9
TMT 2.8
microsomal epoxide hydrolase 2.8
SPS 2.8
MMP-3 2.7
p100 2.6
chondroitinase 2.5
chondroitinase 2.4
21-hydroxylase 2.3
Thy1 2.2
ceruloplasmin 2.1
11beta-hydroxysteroid dehydrogenase 2.1
SPC 2.1
alkaline phosphatase 2.0
deoxyribonuclease 1.9
deoxyribonuclease 1.9
thyroid peroxidase 1.8
caspase-1 1.8
aldehyde dehydrogenase 1.8
leucine aminopeptidase 1.8
dipeptidyl peptidase IV 1.7
phosphoglucose isomerase 1.7
paraoxonase 1.7
cathepsin G 1.6
gamma-glutamyl transpeptidase 1.6
prolyl hydroxylase 1.6
prostaglandin synthetase 1.6
PDE 1.6
cathepsin K 1.6
paraoxonase 1.4
MMP 1.4
MIP 1.2
MAP 1.2
peroxiredoxin 1.1
AST 0.9
elastase 0.9
hyaluronidase 0.8
proteasome 0.8
papain 0.8
aldolase 0.7
carbonic anhydrase 0.6
phosphodiesterase 0.6
proteinase K 0.5
neutrophil elastase 0.5
cathepsin B 0.4
pepsin 0.4
MDR 0.3
collagenase 0.3
creatine kinase 0.2
transglutaminase 0.2
kinesin 0.1
deaminase 0.1
adenosine deaminase 0.1
adenosine deaminase 0.1
chymotrypsin 0.0
demethylase 0.0
peroxidase -0.1
trypsin -0.1
AMPK -0.2
alanine aminotransferase -0.3
GSK -0.3
more...
Compound
Ibuproxam 10.4
Radium-224 10.1
Etanercept 9.3
A 435 9.3
Etoricoxib 8.8
Oxaprozin 8.6
Sulfasalazine 8.5
HAQ 8.2
ETN 7.9
Benoxaprofen 7.8
Fenoprofen 7.7
BAS 7.6
Azapropazone 7.3
dIMP 7.1
Homogentisate 6.8
Phthalimide 6.8
Red R 6.8
IBP 6.7
IBP 6.7
CZP 6.7
Propoxyphene 6.6
Flucloxacillin 6.5
B17 6.4
Rifamycin 6.4
238A 6.2
Meclofenamate 6.1
Rifamycin 6.1
Meloxicam 6.1
Rifamycin 6.0
2-naphthylacetic acid 6.0
Auramine 5.8
Phenylbutazone 5.7
Naproxen 5.5
Pamidronate 5.4
Piroxicam 5.4
Rifamycin 5.4
Captan 5.3
C 5 5.3
Polydatin 5.3
Orange G 5.2
Diflunisal 5.2
Diclofenac 5.2
Leflunomide 5.1
TNF 5.1
Sulindac 5.1
Tumor Necrosis Factor 5.0
Rofecoxib 4.9
Levamisole 4.8
phenylacetic acid 4.7
phenylacetic acid 4.7
phenylacetic acid 4.7
T11 4.6
Relaxant 4.6
ANCA 4.6
Celecoxib 4.5
Triamcinolone 4.5
PBG 4.5
ASK 4.5
phenylacetic acid 4.5
Ketoprofen 4.5
INN 4.4
Propafenone 4.4
BIP 4.4
S 1 4.4
CCP 4.4
TAP 4.3
MHS 4.3
DMB 4.3
Methotrexate 4.2
Naringin 4.2
ANA 4.2
ANA 4.2
MTX 4.1
MEP 4.1
Puromycin 4.0
DMB 4.0
MEP 3.9
PMS 3.7
Moxifloxacin 3.6
Guo 3.6
more...