Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P01889 (
ankylosing spondylitis
)
5,717
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
ankylosing spondylitis
5717
HLA-B27
771
B27
540
HLA
471
TNF
371
Sep
337
tumor necrosis factor
275
C-reactive protein
217
cytokine
163
IgA
145
IL-17
117
TNF-alpha
103
human leukocyte antigen
102
CRP
98
rheumatoid factor
96
ESR
95
MRI
90
gut
84
Mol
82
major histocompatibility complex
74
HLA-B
64
IL-23
61
Tumor necrosis factor
56
collagen
51
IL-6
48
MHC
48
endoplasmic reticulum
47
tumor necrosis factor alpha
46
HLA-B*27
43
ERAP1
41
CD4
37
alkaline phosphatase
35
CD8
34
heavy chain
34
B*2706
34
Mal
34
HLA class I
33
She
32
histocompatibility antigen
30
IL-1
30
asymmetrical
29
IL23R
27
lymphoid
27
insulin
25
HLA-A
25
interleukin-17
25
HLA B
24
proteoglycan
24
Hip
24
MHC class I
23
TNF receptor
23
interferon
21
fused
20
cage
19
HLA-DR4
19
Endoplasmic reticulum aminopeptidase 1
18
IL-10
17
DR4
17
IFN
17
Human leukocyte antigen
17
hemoglobin
16
aminopeptidase
16
interleukin-6
16
IL-4
16
lipopolysaccharide
15
type II collagen
15
human leucocyte antigen
15
ANA
14
parathyroid hormone
14
IBD
13
B13
13
osteocalcin
13
COX-2
13
major histocompatibility complex class I
12
ERAP2
12
osteogenic
12
renal amyloidosis
12
Pol
12
TCR
12
IL-22
12
more...
Disease
ankylosing spondylitis
5709
rheumatoid arthritis
1627
arthritis
1091
psoriatic arthritis
889
HLA-B27
771
psoriasis
474
systemic lupus erythematosus
396
osteoarthritis
353
sacroiliitis
318
Crohn's disease
316
inflammatory bowel disease
311
Reiter's syndrome
282
spondyloarthropathy
247
uveitis
243
spondylitis
189
anterior uveitis
172
ulcerative colitis
168
enthesitis
162
arthropathy
158
arthrodesis
154
tuberculosis
141
juvenile rheumatoid arthritis
130
osteoporosis
125
Klebsiella
110
gout
106
hyperostosis
102
cancer
101
vasculitis
99
PSS
86
autoimmune disease
85
multiple sclerosis
84
synovitis
82
sarcoidosis
74
rheumatism
74
lupus
70
Spondyloarthritis
68
tumor
67
polyarthritis
67
fibromyalgia
66
Best
66
lupus
64
depression
62
diabetes
62
amyloidosis
61
cauda equina syndrome
60
aortic regurgitation
56
plaque
56
Yersinia
56
enthesopathy
52
cardiovascular disease
49
dermatomyositis
48
scleroderma
47
hypertension
44
atherosclerosis
43
polymyositis
43
iritis
40
dactylitis
40
osteitis
37
Behcet's disease
37
infectious diseases
33
chronic pain
31
asthma
30
mimicry
30
familial Mediterranean fever
30
lymphoma
29
colitis
29
leukemia
29
polymyalgia rheumatica
28
IgA nephropathy
27
mixed connective tissue disease
27
proteinuria
27
celiac disease
26
rash
26
Diffuse idiopathic skeletal hyperostosis
26
erythema nodosum
25
Still's disease
25
pyoderma gangrenosum
24
SLE
24
Chlamydia
24
systemic disease
24
more...
Symptom
pain
578
back pain
204
low back pain
117
fatigue
73
anesthesia
50
arthralgia
49
diarrhea
38
neck pain
36
weakness
35
headache
26
abdominal pain
21
discomfort
19
discomfort
19
dyspnea
18
chronic back pain
17
hip pain
17
cough
15
heel pain
15
sciatica
12
nausea
11
analgesia
11
swollen joints
10
chest pain
9
acute pain
9
distraction
9
shoulder pain
8
knee pain
8
numbness
8
dizziness
8
hemoptysis
8
paraparesis
7
paresthesia
7
regurgitation
7
erythema
6
dry eye
5
seizures
5
bone pain
5
paresis
5
vertigo
4
myalgia
4
vomiting
4
collapse
4
polymyalgia
4
anorexia
4
tinnitus
4
asthenia
4
leg pain
4
insomnia
4
Stiffness
4
clubbing
4
night sweats
3
thinning
3
spasm
3
shortness of breath
3
generalized pain
3
dystonia
3
respiratory distress
3
Poor sleep
3
groin pain
3
livedo
2
cachexia
2
cancer pain
2
functional recovery
2
thigh pain
2
dark urine
2
Hyperextension
2
arm pain
2
overweight
2
spasticity
2
eye pain
2
hemiplegia
2
Musculoskeletal symptoms
2
dysesthesia
2
chronic constipation
2
angina
2
Ill
2
syncope
2
dysarthria
2
dental pain
2
intestinal bleeding
2
more...
Drug
Infliximab
79
Infliximab
79
Dermatol
57
Adalimumab
51
p75
33
Golimumab
25
Monit
15
CSF
13
Sulphasalazine
12
IFN-gamma
10
Tenoxicam
9
CTX
7
Cardiovasc
7
CTX
7
FLP
7
IL-2
7
CTX
7
Indomethacin
7
lysine
6
ABC
6
ROC
6
Etodolac
6
Certolizumab pegol
6
Aceclofenac
5
Diclofenac sodium
5
Rituximab
5
Asthma
4
Nephron
4
PTH
4
IL-1ra
4
Nephron
4
Tuberculin
4
MAP
4
Abatacept
3
Oxaprozin
3
Anakinra
3
Posture
2
Adefovir dipivoxil
2
CAM
2
EPI
2
THA
2
RFP
2
Arthrex
2
Feprazone
2
Nabumetone
2
Asn
2
SPP
2
Auranofin
2
Dial
2
Fenoprofen
2
Alclofenac
2
Leaf
2
Pirprofen
2
ENT
1
Rifaximin
1
Mobic
1
Campath
1
Tiaprofenic acid
1
Lornoxicam
1
Methylprednisolone
1
Arava
1
Rosuvastatin
1
Salmon calcitonin
1
G-CSF
1
Isoxicam
1
SBT
1
CED
1
AMC
1
CaCl2
1
BCG vaccine
1
EE2
1
Gel
1
NAG
1
Fenbufen
1
Check
1
IFN-beta
1
CaCl2
1
NADH
1
ascorbate
1
Triad
1
more...
Enzyme
alkaline phosphatase
35
nitrogenase
13
peroxidase
11
ERK
9
proteasome
9
catalase
7
trypsin
7
superoxide dismutase
6
MDP
6
gamma-glutamyl transpeptidase
5
phosphodiesterase
5
focal adhesion kinase
5
mitogen-activated protein kinase
5
aldehyde dehydrogenase
4
collagenase
4
MMP-3
4
ceruloplasmin
4
alanine aminotransferase
4
creatine kinase
4
caspase-1
4
elastase
3
luciferase
3
MAP
3
type III procollagen
3
protein kinase
3
glutathione peroxidase
3
aspartate aminotransferase
3
glutathione S-transferase
2
PDE
2
hyaluronidase
2
proteinase-3
2
pullulanase
2
pepsin
2
neuraminidase
2
carbonic anhydrase
2
MMP
2
uricase
2
chymotrypsin
2
oxytocinase
2
SPC
2
papain
2
ACE
2
thyroid peroxidase
2
thrombin
2
MIP
2
chondroitinase
2
chondroitinase
2
AST
2
proteinase K
1
tissue plasminogen activator
1
plasmin
1
urokinase-type plasminogen activator
1
deoxyribonuclease
1
chymopapain
1
endonuclease
1
deaminase
1
CD10
1
acid phosphatase
1
cathepsin K
1
homogentisate 1,2-dioxygenase
1
AMPK
1
peptidylarginine deiminase
1
ATPase
1
CDH
1
11beta-hydroxysteroid dehydrogenase
1
methionine synthase reductase
1
aldolase
1
urease
1
lysozyme
1
cathepsin G
1
DNA polymerase
1
dipeptidyl peptidase IV
1
caspase-3
1
GSK
1
ATP synthase
1
AMPK
1
prostaglandin synthetase
1
transglutaminase
1
AMP-activated protein kinase
1
calcineurin
1
more...
Compound
Clin
1042
Dec
425
TNF
371
DNA
84
Etanercept
71
calcium
54
His
41
Sulfasalazine
29
sodium
29
arginine
28
vitamin D
24
glucose
22
oxygen
21
HAQ
20
Cardiol
19
Methotrexate
17
leucine
17
BAS
17
phosphate
15
ANA
14
ANA
14
tyrosine
13
water
13
cysteine
13
PEG
13
Asp
13
lysine
11
phosphorus
10
creatinine
9
homocysteine
9
acetate
9
ANCA
8
salt
8
zinc
8
iron
8
Etoricoxib
8
propionic acid
8
B17
8
propionic acid
8
T11
8
sulfate
7
Phe
7
CTX
7
BMD
7
Diclofenac
7
Guo
7
Indomethacin
7
MTX
7
copper
7
Guo
7
Hearts
6
nitric oxide
6
TAP
6
CCP
6
alanine
6
nitrogen
6
Abbott
5
Tumor Necrosis Factor
5
CO2
5
phenylacetic acid
5
phenylacetic acid
5
Naproxen
5
ethanol
5
phenylacetic acid
5
T10
5
phenylacetic acid
5
hyaluronic acid
4
aspartic acid
4
Celecoxib
4
Insulin
4
Congo red
4
A 42
4
Levamisole
4
Vitamin D
4
aspartic acid
4
ACTH
4
Meloxicam
4
DBA
4
aspartic acid
4
acetic acid
4
more...