Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P01889 (ankylosing spondylitis)
 5,717 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
transmembrane and tetratricopeptide repeat containing 1 12.4
HLA-B*2712 12.4
ankyrin repeat domain 38 12.4
TTC38 12.4
ankylosing spondylitis 12.4
phospholipase D family, member 4 12.4
Major histocompatibility complex, class I, B 12.4
MRPL22 12.4
PADI 1 12.4
Peptidyl arginine deiminase, type IV 11.4
B*2706 11.4
HLA-B27 mRNA 11.4
MRPL25 11.4
HLA-B27 10.9
SAP30BP 10.9
craniofacial development protein 1 10.9
Leukocyte immunoglobulin-like receptor A3 10.9
G6E 10.9
mitochondrial ribosomal protein S11 10.9
endoplasmic reticulum aminopeptidase 2 10.7
HLA-B*27 10.7
B27 10.6
HLA-B27 protein 10.6
prefoldin subunit 5 10.4
RBP5 10.4
interleukin 17 receptor C 10.4
sterile alpha motif domain containing 9 10.4
HLA-Bw62 antigen 10.4
peptidyl arginine deiminase type IV 10.1
TST2 10.1
HLA class I alpha chain 10.1
ERAP1 10.1
Endoplasmic reticulum aminopeptidase 1 10.0
Fc receptor-like 5 9.9
Interleukin 23 receptor 9.9
HLA B 9.8
leucocyte immunoglobulin-like receptor 9.6
BAT5 9.6
KIF21B 9.6
BRWD1 9.4
HSP70-Hom 9.4
Phospholipase D4 9.3
G6C 9.3
B4GALT3 9.1
LECT1 9.1
integral membrane protein 2A 9.1
IL23R 9.1
ERAP2 9.1
PIP4K2C 9.0
IP6K3 9.0
PSMG1 9.0
protein tyrosine phosphatase receptor type C 9.0
CREG 8.9
killer-cell Ig-like receptor 8.9
SINTBAD 8.6
KLRC4 8.6
ANTXR2 8.5
HLA-B39 8.5
ANKH 8.5
B144 8.4
FCRL5 8.4
MICA protein 8.4
HLA-E protein 8.4
human leukocyte antigen B 8.4
KIR3DS1 8.4
p75 TNF receptor 8.4
TMEM45A 8.4
G6D 8.3
Cw*08 8.3
ribosomal protein L17 8.3
JARID1A 8.3
KIR2DL5A 8.3
OPLL 8.2
B60 8.2
DEFA3 8.2
GNG11 8.2
HAPLN1 8.2
Chloride intracellular channel protein 1 8.2
LILRA3 8.2
histocompatibility antigen 8.2
KIR2DL5 8.1
PSF2 8.1
NO66 8.1
DEL1 8.1
HLA-Cw1 8.1
HLA-B* 8.1
B3GNT2 8.0
proteoglycan link protein 8.0
KIR2DS5 8.0
RN6 8.0
Histocompatibility antigen 8.0
HLA B44 8.0
AHNAK2 7.9
C-X-C chemokine receptor type 5 7.9
FCRL4 7.9
PSF1 7.9
PADI2 7.9
K26 7.9
TREML2 7.9
DHRS3 7.7
RPL17 7.7
KIR3DL2 7.7
IL-1F10 7.7
NVL 7.7
IL-23R 7.7
PADI4 7.7
HLA-2 7.6
NG30 7.5
PSMA4 7.5
PSTPIP 7.5
orosomucoid 1 7.5
TNAP 7.5
A27 7.5
CL-43 7.5
AGK 7.5
HLA-B38 7.5
Chemokine-like factor 7.5
GALE 7.5
LST1 7.4
class I histocompatibility antigen 7.4
ADORA3 7.4
CCNF 7.4
HLA-B57 7.4
KPNA1 7.4
MUC19 7.4
ZMIZ1 7.4
LTBR 7.3
HLA-DNA 7.3
HLA protein 7.3
gliomedin 7.3
IRF-5 7.2
ME1 7.2
NKX2-3 7.2
CCP3 7.2
C1R 7.2
HLA-B51 7.2
HLA-DMA 7.2
LPIN2 7.2
UBE2D1 7.2
PSMA6 7.2
VIPR1 7.2
TNIP1 7.1
JMY 7.1
VH4-34 7.1
HLA-B 7.1
MHC class I protein 7.0
MAGI-3 7.0
SASP 7.0
Naf1 7.0
PG-Lb 7.0
tapasin 6.9
KIR3DL1 6.9
SART3 6.9
TNFRSF25 6.9
HLA-A*68 6.9
HLA-B15 6.9
HLA-A33 6.9
Human leukocyte antigen 6.8
MAPK7 6.8
HLA-DRB1*01 6.8
more...
Disease
Reactive arthropathy 12.4
Juvenile spondyloarthropathy 12.4
Follicular occlusion triad 12.4
Necrotizing esophagitis 12.4
ankylosing spondylitis 12.3
Romanus lesion 11.7
Acute uveitis 11.4
Acute anterior uveitis 11.4
Juvenile ankylosing spondylitis 11.2
sacroilitis 11.1
Vertebral osteoporosis 11.1
HLA-B27 10.9
yersinia enteritis 10.9
Skin deposits 10.9
Seronegative arthritis 10.9
sacroiliitis 10.8
MS-like syndrome 10.6
Spondyloarthritis 10.5
Esophageal infections 10.4
Reiter's syndrome 10.3
enthesitis 10.3
Seropositive rheumatoid arthritis 10.3
spondyloarthropathy 10.3
psoriatic arthritis 10.2
Enteropathic arthritis 10.1
Osteitis condensans ilii 9.9
Secondary osteoarthritis 9.9
enthesopathy 9.7
Lupus-like syndrome 9.6
Gastrointestinal amyloidosis 9.6
spondylitis 9.6
Juvenile psoriatic arthritis 9.4
Intervertebral disc calcification 9.4
anterior uveitis 9.3
Alkaptonuric ochronosis 9.3
Bony ankylosis 9.3
Plasma cell infiltration 9.3
dactylitis 9.2
digestive infection 9.1
panmyelophthisis 9.1
Protrusio acetabuli 9.1
Gastrointestinal inflammation 9.0
Launois 9.0
Ochronotic arthropathy 8.9
cauda equina syndrome 8.9
Reactive arthritis 8.9
cervical spine syndrome 8.9
Band keratopathy 8.9
Posterior synechiae 8.9
Diffuse idiopathic skeletal hyperostosis 8.8
Posterior uveitis 8.8
Inflammatory disease 8.7
Posner-Schlossman syndrome 8.7
Necrotizing scleritis 8.6
Phlyctenular keratoconjunctivitis 8.6
Idiopathic hypoparathyroidism 8.5
Erythrodermic psoriasis 8.5
PUVA lentigines 8.5
Non-secretory myeloma 8.5
coxitis 8.5
iritis 8.5
Spinal epidural hematoma 8.4
Cauda equina 8.4
hyperostosis 8.4
renal scleroderma 8.4
cervical disc degeneration 8.3
juvenile rheumatoid arthritis 8.2
OPLL 8.2
Erosive osteoarthritis 8.2
Chronic periaortitis 8.2
Bronchocentric granulomatosis 8.1
polyarthrosis 8.1
familial hypophosphatemia 8.1
migratory arthritis 8.0
Mild depression 8.0
spondylopathy 7.9
Bone marrow edema 7.9
iridocyclitis 7.9
cervical arthritis 7.7
Pulmonary vasculitis 7.7
Yersinia enterocolitica infection 7.7
inflammatory joint disease 7.6
Achilles tendinitis 7.6
spondylosis 7.6
polyarticular arthritis 7.6
Aspergilloma 7.6
pseudogout 7.6
uveitis 7.5
arthritis of the wrist 7.5
Still's disease 7.5
Acne fulminans 7.5
Scheuermann's disease 7.5
Atlantoaxial instability 7.4
rheumatoid arthritis 7.4
Carcinoma cuniculatum 7.4
Drug eruption 7.4
SA block 7.4
Behcet's disease 7.4
Haglund's deformity 7.4
MSSD 7.4
Myofascial pain 7.3
Osteitis pubis 7.3
AA amyloidosis 7.3
episcleritis 7.2
Geographic atrophy 7.2
GALE 7.2
rheumatism 7.2
cyclitis 7.2
shoulder syndrome 7.2
Retinal vasculitis 7.2
Fuchs' heterochromic cyclitis 7.1
Cervical myelopathy 7.1
TINU 7.1
capsulitis 7.1
Witts 7.0
calcaneal spur 7.0
Macrophage activation syndrome 7.0
polymyalgia rheumatica 7.0
psoriasis 7.0
Klebsiella infection 7.0
Plaque psoriasis 7.0
Aspergillus pneumonia 6.9
ochronosis 6.9
sclerokeratitis 6.9
Aortic rupture 6.9
Whipple's disease 6.9
Jaccoud 6.9
Nail psoriasis 6.9
arthritis of the knee 6.9
mixed connective tissue disease 6.9
gout 6.8
Primary osteoarthritis 6.8
aortitis 6.8
Steinbrocker 6.8
chondrocalcinosis 6.8
valvulitis 6.8
pars planitis 6.8
osteitis 6.8
polyarthritis 6.8
polychondritis 6.8
Erythema elevatum diutinum 6.7
scleromalacia 6.7
chronic bronchiolitis 6.7
SAPHO syndrome 6.7
arthropathy 6.7
inflamed eye 6.7
malignant fibrous histiocytoma of bone 6.7
arthrodesis 6.7
Chronic arthritis 6.7
infectious arthritis 6.6
incomplete paraplegia 6.6
fibrothorax 6.6
Sjogren's syndrome 6.6
discitis 6.6
drug induced lupus 6.6
Secondary glaucoma 6.6
hydroxyapatite deposition 6.5
Renal amyloidosis 6.5
familial Mediterranean fever 6.5
Crush syndrome 6.5
more...
Symptom
Sacroiliac joint laxity 12.4
Ochronotic pigmentation 12.4
Intermittent fever 8.7
vaginal discomfort 8.0
rib pain 8.0
pain in the buttock 7.7
polymyalgia 7.6
heel pain 7.5
Hyperextension 7.1
Cardiovascular symptoms 7.1
Radicular pain 7.0
chronic back pain 7.0
Livedoid 6.8
Musculoskeletal symptoms 6.7
postpartum pain 6.7
swollen joints 6.7
thoracic back pain 6.7
back pain 6.5
generalized pain 6.4
painful swallowing 6.4
low back pain 6.0
Overlying 6.0
lumbar instability 6.0
hip pain 5.7
cardiovascular impairment 5.7
neck pain 5.7
Poor sleep 5.5
sciatica 5.4
acute low back pain 5.3
dark urine 5.3
arthralgia 5.2
Severe pain 5.1
eye pain 4.9
pedal edema 4.7
clubbing 4.6
disturbed balance 4.6
aphonia 4.5
Stiffness 4.5
arm pain 4.5
groin pain 4.5
body pain 4.4
non-productive cough 4.3
urethral discharge 4.2
right lower quadrant pain 4.2
loin pain 4.1
Physical findings 4.1
thigh pain 4.1
shoulder pain 4.0
knee pain 4.0
loss of taste 3.9
paraparesis 3.8
night sweats 3.8
intestinal bleeding 3.8
livedo 3.7
acute pain 3.7
pain 3.6
Halo 3.6
motor symptom 3.6
dysesthesia 3.6
stomach pain 3.5
leg pain 3.4
dry eye 3.4
hyperesthesia 3.4
ankle pain 3.4
mental fatigue 3.3
Gastrointestinal symptoms 3.3
pleuritic chest pain 3.2
dental pain 3.2
neck stiffness 3.2
bone pain 3.2
rales 3.1
chronic constipation 3.1
numbness 3.1
asthenia 3.1
limb pain 3.1
paresthesia 3.0
fatigue 3.0
hemoptysis 2.9
renal colic 2.8
muscle cramps 2.6
distraction 2.4
weakness 2.4
urinary frequency 2.3
productive cough 2.3
hypoproteinemia 2.3
paresis 2.3
regurgitation 2.2
discomfort 2.2
dizziness 2.2
muscle stiffness 2.2
discomfort 2.1
Neuropathic pain 2.0
abdominal pain 1.9
diarrhea 1.9
anosmia 1.9
cancer pain 1.9
dyspnea 1.8
photophobia 1.8
cough 1.8
despair 1.8
torticollis 1.8
myalgia 1.8
tinnitus 1.8
shortness of breath 1.7
neuralgia 1.7
vertigo 1.6
dysarthria 1.6
chest pain 1.5
hemiplegia 1.5
chronic cough 1.5
fever of unknown origin 1.4
chorea 1.4
nausea 1.4
headache 1.4
erythema 1.3
anesthesia 1.3
rhinorrhea 1.3
dysuria 1.2
spasm 1.2
tachypnea 1.1
analgesia 1.1
insomnia 1.1
sore throat 1.0
dystonia 1.0
cachexia 1.0
hoarseness 0.9
spasticity 0.8
exertional dyspnea 0.7
epigastric pain 0.7
anorexia 0.7
cerebellar ataxia 0.6
thinning 0.6
apathy 0.4
chills 0.4
syncope 0.3
Ill -0.0
lethargy -0.0
sleepiness -0.2
respiratory distress -0.2
functional recovery -0.3
collapse -0.4
vomiting -0.5
nausea and vomiting -0.8
splenomegaly -0.8
constipation -0.9
angina -0.9
overweight -1.2
stigma -1.3
ataxia -1.5
seizures -1.5
Drug
Golimumab 10.8
Feprazone 9.7
Alclofenac 9.7
Aristocort 9.6
Certolizumab pegol 9.2
Mobic 9.1
Adalimumab 9.1
Sulphasalazine 8.8
Tenoxicam 8.6
Infliximab 8.6
Infliximab 8.6
Aceclofenac 8.4
Pirprofen 8.4
Oxaprozin 8.1
Etodolac 8.1
Meclomen 7.9
Iguratimod 7.8
Fenoprofen 7.5
Isoxicam 7.5
Meclomen 7.4
Feldene 7.2
Fenbufen 6.9
Nabumetone 6.8
Lornoxicam 6.5
Adefovir dipivoxil 6.5
Arava 6.5
Tiaprofenic acid 6.5
Profenid 6.5
Abatacept 6.4
Anakinra 6.1
Diclofenac sodium 6.0
Anafranil 5.7
p75 5.6
Celebrex 5.5
Arthrex 5.5
Tuberculin 5.3
FLP 5.2
Auranofin 5.1
Salmon calcitonin 4.9
SPP 4.9
Novantrone 4.8
Rifaximin 4.7
IL-1ra 4.0
SBT 3.8
Rosuvastatin 3.6
THA 3.6
Moxifloxacin 3.6
Denosumab 3.3
Streptokinase 3.3
Rituximab 3.3
CED 3.3
RFP 3.2
Budesonide 3.1
Triad 3.0
Camp 2.9
Campath 2.9
Campath 2.9
CIA 2.8
CTX 2.8
CTX 2.8
Indomethacin 2.6
Methylprednisolone 2.6
Isoniazid 2.5
Omeprazole 2.5
Prednisone 2.5
EPI 2.4
BCG vaccine 2.3
AMC 2.2
Vitamin B12 2.2
ROC 2.1
Pronase 2.1
CTX 1.9
ABC 1.9
PTH 1.7
Diurnal 1.7
Check 1.5
NAG 1.4
Monit 1.3
CSF 1.2
Fluorescein 1.0
Posture 1.0
IFN-gamma 0.9
CAM 0.9
Nephron 0.9
IFN-beta 0.9
Heme 0.8
Retinoic acid 0.7
Fluorescein 0.6
MAP 0.5
IL-2 0.4
Nephron 0.3
Dermatol 0.3
G-CSF 0.1
Asn -0.1
CaCl2 -0.2
CaCl2 -0.2
Asthma -0.2
CaCl2 -0.2
EE2 -0.5
ENT -0.6
nitroglycerin -0.7
lysine -0.8
Leaf -1.0
Gel -1.4
Dial -1.5
vitamin E -1.7
ROS -1.8
NADH -2.0
ascorbate -2.1
Cardiovasc -2.4
Enzyme
galactosylhydroxylysyl glucosyltransferase 6.1
oxytocinase 5.6
aminopeptidase I 5.5
proteinase-3 5.0
homogentisate 1,2-dioxygenase 4.9
Lod 4.8
methionine synthase reductase 4.8
type III procollagen 4.6
nitrogenase 4.3
dimethylarginine dimethylaminohydrolase 4.2
peptidylarginine deiminase 4.0
pullulanase 3.9
chymopapain 3.8
chymopapain 3.7
factor D 3.6
MDP 3.6
prolidase 3.5
CDH 3.3
uricase 3.2
alanine aminopeptidase 2.9
TMT 2.8
microsomal epoxide hydrolase 2.8
SPS 2.8
MMP-3 2.7
p100 2.6
chondroitinase 2.5
chondroitinase 2.4
21-hydroxylase 2.3
Thy1 2.2
ceruloplasmin 2.1
11beta-hydroxysteroid dehydrogenase 2.1
SPC 2.1
alkaline phosphatase 2.0
deoxyribonuclease 1.9
deoxyribonuclease 1.9
thyroid peroxidase 1.8
caspase-1 1.8
aldehyde dehydrogenase 1.8
leucine aminopeptidase 1.8
dipeptidyl peptidase IV 1.7
phosphoglucose isomerase 1.7
paraoxonase 1.7
cathepsin G 1.6
gamma-glutamyl transpeptidase 1.6
prolyl hydroxylase 1.6
prostaglandin synthetase 1.6
PDE 1.6
cathepsin K 1.6
paraoxonase 1.4
MMP 1.4
MIP 1.2
MAP 1.2
peroxiredoxin 1.1
AST 0.9
elastase 0.9
hyaluronidase 0.8
proteasome 0.8
papain 0.8
aldolase 0.7
carbonic anhydrase 0.6
phosphodiesterase 0.6
proteinase K 0.5
neutrophil elastase 0.5
cathepsin B 0.4
pepsin 0.4
MDR 0.3
collagenase 0.3
creatine kinase 0.2
transglutaminase 0.2
kinesin 0.1
deaminase 0.1
adenosine deaminase 0.1
adenosine deaminase 0.1
chymotrypsin 0.0
demethylase 0.0
peroxidase -0.1
trypsin -0.1
AMPK -0.2
alanine aminotransferase -0.3
GSK -0.3
ATP synthase -0.3
neuraminidase -0.4
aspartate aminotransferase -0.4
urease -0.4
NOS -0.4
glutathione peroxidase -0.4
urease -0.4
DNase -0.5
catalase -0.5
lipoxygenase -0.6
focal adhesion kinase -0.7
plasmin -0.7
ACE -0.7
transcriptase -0.8
CD10 -0.8
superoxide dismutase -0.8
ERK -0.9
urokinase-type plasminogen activator -0.9
glutathione S-transferase -1.0
tissue plasminogen activator -1.0
AMPK -1.2
luciferase -1.2
acid phosphatase -1.2
AMP-activated protein kinase -1.2
beta-galactosidase -1.4
thrombin -1.6
DNA polymerase -1.6
calcineurin -1.6
endonuclease -1.7
mitogen-activated protein kinase -1.8
lysozyme -1.9
protein kinase -2.3
lactate dehydrogenase -2.4
reverse transcriptase -2.5
RNA polymerase -2.6
caspase-3 -2.7
ATPase -3.6
Compound
Ibuproxam 10.4
Radium-224 10.1
Etanercept 9.3
A 435 9.3
Etoricoxib 8.8
Oxaprozin 8.6
Sulfasalazine 8.5
HAQ 8.2
ETN 7.9
Benoxaprofen 7.8
Fenoprofen 7.7
BAS 7.6
Azapropazone 7.3
dIMP 7.1
Homogentisate 6.8
Phthalimide 6.8
Red R 6.8
IBP 6.7
IBP 6.7
CZP 6.7
Propoxyphene 6.6
Flucloxacillin 6.5
B17 6.4
Rifamycin 6.4
238A 6.2
Meclofenamate 6.1
Rifamycin 6.1
Meloxicam 6.1
Rifamycin 6.0
2-naphthylacetic acid 6.0
Auramine 5.8
Phenylbutazone 5.7
Naproxen 5.5
Pamidronate 5.4
Piroxicam 5.4
Rifamycin 5.4
Polydatin 5.3
Captan 5.3
C 5 5.3
Orange G 5.2
Diflunisal 5.2
Diclofenac 5.2
Leflunomide 5.1
TNF 5.1
Sulindac 5.1
Tumor Necrosis Factor 5.0
Rofecoxib 4.9
Levamisole 4.8
phenylacetic acid 4.7
phenylacetic acid 4.7
phenylacetic acid 4.7
T11 4.6
Relaxant 4.6
ANCA 4.6
Celecoxib 4.5
Triamcinolone 4.5
PBG 4.5
ASK 4.5
phenylacetic acid 4.5
Ketoprofen 4.5
INN 4.4
Propafenone 4.4
BIP 4.4
S 1 4.4
CCP 4.4
TAP 4.3
MHS 4.3
DMB 4.3
Methotrexate 4.2
Naringin 4.2
ANA 4.2
ANA 4.2
MTX 4.1
MEP 4.1
Puromycin 4.0
DMB 4.0
MEP 3.9
PMS 3.7
Moxifloxacin 3.6
Guo 3.6
MNA 3.6
MNA 3.6
T10 3.6
BMD 3.5
Hydroxychloroquine 3.5
Naringin 3.5
D-Ala-D-Ala 3.5
Xenon 3.4
Ibuprofen 3.3
Mycophenolate mofetil 3.2
Isoform 3.2
CDH 3.1
Homocysteine 3.1
Homocysteine 3.1
prostaglandin F1 3.1
DOS 3.1
CES 3.0
Guo 3.0
Wellcome 3.0
Spironolactone 2.9
A 42 2.9
A 71 2.9
Abbott 2.9
3-methylhistidine 2.8
propionic acid 2.8
propionic acid 2.8
PAG 2.8
Indomethacin 2.8
Hearts 2.8
HfO2 2.7
Methylprednisolone 2.7
Acetazolamide 2.7
TCC 2.6
Pima 2.6
Ceftriaxone 2.6
DRB 2.5
PPD 2.5
Congo red 2.5
Imipramine 2.5
Imipramine 2.5
DMN 2.5
PDH 2.5
PPi 2.5
Azathioprine 2.5
PPD 2.4
PBE 2.4
Neo 2.3
TIC 2.3
Atorvastatin 2.3
Calcitonin 2.3
Rose Bengal 2.3
Coronal 2.3
INH 2.3
vitamin D 2.3
Leucine 2.2
Omeprazole 2.2
PAN 2.2
keratan sulfate 2.2
homocysteine 2.1
GGG 2.1
PEA 2.1
Formal 2.0
1,1'-biphenyl 2.0
Nitrite 1.9
CTX 1.9
Clin 1.9
DPA 1.9
DPA 1.9
DPA 1.9
DPA 1.9
DPA 1.9
Prednisone 1.8
Tetracycline 1.8
Vitamin D 1.7
SPF 1.7
APAP 1.6
DOPAC 1.6
PVP 1.6
His 1.5
MCP 1.5
more...