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Query: UNIPROT:P01889 (ankylosing spondylitis)
 5,717 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In a group of 55 men of 18 to 58 years of age who were suffering from ankylosing spondylitis, changes in lung function were analysed by measuring the static parameters and by differentiating between the thoracic and abdominal parts in breathing at rest and under stress, using CO2 rebreathing. In accordance with the reduction in vital capacity, the thoracic share is restricted already at rest. At rest, there is compensation via the abdominal compartment, in contrast to the stress in CO2 rebreathing in which the abdominal part does not compensate.
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PMID:[Diagnosis of lung function in patients with ankylosing spondylitis]. 236 31

Fractures in ankylosing spondylitis (AS) are often difficult to identify and treat. If combined with osteoporosis, the spine becomes weaker and vulnerable to minor trauma. An 83-year-old woman with a history of chronic AS and severe osteoporosis developed paraparesis and voiding difficulty for 4 days prior. She had been placed in the lateral decubitus position in a bedridden state in a convalescent hospital due to the progressive paraparesis. The laboratory findings showed CO2 retention in the arterial blood gas analysis. After the patient was transferred to the computed tomography (CT) room, a CT was taken in the supine position. Approximately half an hour later, the resident in our neurosurgical department checked on her, and the neurological examination showed a complete paraplegic state. She was treated conservatively and finally expired 20 days later.
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PMID:Leading a Patient of Ankylosing Spondylitis to Death by Iatrogenic Spinal Fracture. 2743 20