Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P01889 (
ankylosing spondylitis
)
5,717
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Anti-tumor necrosis factor (TNF) agents have become central players in the management of autoimmune and rheumatic disease. With the wide use of anti-TNF agents today, we have become aware of rare autoimmune complications as systemic lupus erythematosus and psoriasis, yet rarely has large vessels vasculitis been described. We herein describe a case of cytoplasmic anti-neutrophil cytoplasmic antibody (c-ANCA) (with
myeloperoxidase
(
MPO
) antibodies)-associated large vessel vasculitis (aortitis) that developed during anti-TNF treatment for
ankylosing spondylitis
. Awareness of this rare, but serious, adverse event of these commonly used agents in rheumatic diseases is of importance.
...
PMID:Etanercept treatment-related c-ANCA-associated large vessel vasculitis. 2662 31
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