Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P01889 (ankylosing spondylitis)
 5,717 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Patients with ankylosing spondylitis frequently experience back pain and they have a well-known propensity for spinal fractures, but they rarely manifest motor and sensory nerve root impairment. We recently encountered a patient with ankylosing spondylitis who complained of classical spinal claudication with urinary sphincter dysfunction. Computed axial tomography revealed marked lumbosacral lateral recess and foraminal spinal stenosis that was not evident on the myelogram; at operation the stenosis appeared to be the result of extensive posterior soft tissue ossification. This heretofore unrecognized yet potentially treatable complication of ankylosing spondylitis is discussed.
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PMID:Symptomatic spinal stenosis associated with ankylosing spondylitis. 715 36

Enlargement of the caudal sac with bony erosions of the spinal vertebrae may be a late sequel of ankylosing spondylitis. CT scans demonstrate typical changes. We report a case with spinal claudication and a neuropathic ulcer.
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PMID:[Spinal claudication and malum perforans pedis. Late sequela of ankylosing spondylitis (Bechterew disease) with cystic lumbosacral arachnopathy]. 785 10