Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P01889 (ankylosing spondylitis)
 5,717 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A cauda equina syndrome in association with ankylosing spondylitis is well recorded. We report the occurrence of an upper limb radiculopathy which progressed to a cauda equina syndrome in association with ankylosing spondylitis.
 ...
PMID:Radiculopathy as a complication of ankylosing spondylitis. 20 53

This article describes a case of the cauda equina syndrome associated with ankylosing spondylitis. The typical myelographic features and the computerized tomography (CT) scan of the lumbar spine are included. The CT scan may aid in elucidating the pathogenesis of the disorder.
 ...
PMID:Computerized tomography. An adjunct to early diagnosis in the cauda equina syndrome of ankylosing spondylitis. 62 30

Three patients with the combination of long-standing ankylosing spondylitis (AS) and cauda equina syndrome are described and compared with 17 from the literature. The nerve root lesion has been of gradual onset and has since the time of diagnosis either been stationary or progressed slowly. Radicular pain in the feet and legs, and genito-urinary complaints have been the dominant and most disabling symptoms. Typical myelographic findings were expansion of the dural sac and arachnoidal diverticula. There is a highly probable relationship between AS and the neurological syndrome. The pathogenesis is probably related to early arachnoiditis with subsequent loss of meningeal elasticity. Earlier recognition of the root lesion may result in a more effective treatment.
 ...
PMID:Cauda equina lesions in ankylosing spondylitis. 89 86

Six patients with ankylosing spondylitis and features of a cauda equina syndrome are described. The myelographic findings are discussed in relation to the pathogenesis of the disorder and its natural history. Present experience suggests that the cauda equina syndrome is a more common complication of ankylosing spondylitis than is usually thought.
 ...
PMID:Cauda equina syndrome in ankylosing spondylitis: a report of six cases. 101 Oct 27

The clinical and radiological findings in a patient with long-standing ankylosing spondylitis who developed the clinical features of a cauda equina syndrome are presented. CT and MRI revealed characteristic expansion of the lumbar spinal canal with scalloping of the laminae and spinous processes related to the presence of dorsal dural diverticulae. MRI permitted confident exclusion of other intradural pathology without recourse to invasive investigations.
 ...
PMID:Case report: CT and MRI of the cauda equina syndrome in ankylosing spondylitis. 173 29

Four new cases of ankylosing spondylitis complicated by a cauda equina syndrome are reported. Similarly to the previous descriptions, the patients present with long-standing and severe spondylitis at the time when neurological symptoms, mainly radicular pain, develop. Computed tomography of the lumbar spine demonstrates in all cases typical laminar erosions and posterior arachnoid diverticula. Up to now, magnetic resonance imaging has rarely been performed in this particular pathology, though it is helpful in determining the anatomical relations and the nature of the lesions. Based on the previous publications, our study aims at describing the clinical and pathogenic aspects of the disease and defining the most useful diagnostic investigations and treatment choices. Therapeutic possibilities are often limited because of a late diagnosis. Better knowledge of this rare complication could lead to earlier recognition and more efficient therapy.
 ...
PMID:[Ankylosing spondylarthritis and partial cauda equina syndrome. Apropos of 4 cases and review of the literature]. 192 99

The evolution of diagnostic imaging has been recently characterized by a wish for a better understanding of pathogenesis of diseases and by technologic progress. Many authors published papers reexamining old myths and old concepts of osteoarthritis. Correlations between clinical data, radiologic data, and MR findings have allowed better definition of the characteristics of osteoarthritis of the knee. MR imaging is of great value in evaluating rheumatoid arthritis in the early stages and in certain locations such as the cervical spine and temporomandibular joint. New imaging techniques, especially CT and MR imaging, are also useful for accurately diagnosing Andersson lesions and cauda equina syndrome in ankylosing spondylitis as well as sacroiliac joint abnormalities in Crohn's disease.
 ...
PMID:Imaging of arthropathies and disorders of connective tissue. 193 10

Typical cauda equina syndrome secondary to long-standing ankylosing spondylitis is reported in a 63-year-old man. Radionuclide cisternography demonstrated a resorption defect of cerebrospinal fluid in the enlarged lumbosacral dural sac. After transient symptomatic improvement with acetazolamide, a lumboperitoneal shunt was placed. The rate of cerebrospinal fluid, isotope resorption became normal. In the 5 years of follow-up, partial remission has been observed.
 ...
PMID:Cerebrospinal fluid dynamics in the tardive cauda equina syndrome of ankylosing spondylitis. 201 91

Cauda equina type of syndrome with neuropathic bladder is a rare but known complication of long-standing ankylosing spondylitis. From 1968 until now, diverticula from the subarachnoid space eroding into the bodies of the lumbosacral vertebrae have been reported in 46 cases of ankylosing spondylitis with cauda equina syndrome and neuropathic bladder. We report 3 cases of neuropathic bladder and ankylosing spondylitis with cauda equina symptoms. In 1 of the 3 patients, these rarely encountered spinal diverticula were demonstrated by computerized tomography (CT) scan. The etiology of these diverticula and their treatment are reviewed.
 ...
PMID:Neuropathic bladder in ankylosing spondylitis with spinal diverticula. 210 19

Cauda equina syndrome as a neurological complication of long-standing ankylosing spondylitis was first reported in 1961. The syndrome is relatively uncommon and its pathophysiology is still poorly understood. Based on their experience with such a case, the authors review the clinical, electrographic, histological, and radiographic features of the syndrome, including the findings of magnetic resonance (MR) imaging. The addition of MR imaging to the evaluation of patients with ankylosing spondylitis and the cauda equina syndrome not only aids in the diagnosis of the syndrome but may also provide valuable insight into the pathophysiology of this condition.
 ...
PMID:Cauda equina syndrome of long-standing ankylosing spondylitis. Case report and review of the literature. 220 Aug 56


1 2 3 4 5 6 Next >>