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Query: UNIPROT:P01889 (ankylosing spondylitis)
 5,717 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The ranges of spinal movement in 390 healthy children aged from 10 to 15 years have been recorded. These measurements are in two planes, anterior and lateral; they are quick and easy to perform and require no special equipment, just a tape measure. Many conditions occurring in childhood can lead to limitation of spinal movement: these include juvenile ankylosing spondylitis, spondylolisthesis, Scheuermann's vertebral osteochondritis, discitis and vertebral fractures, the latter being not uncommon in children receiving prolonged corticosteroid therapy. The purpose of the present paper is to define the normal range for anterior and lateral spinal flexion in adolescents and to correlate these with sex, age, height and weight.
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PMID:Spinal mobility in the adolescent. 49 6

From June, 1989 to March, 1991, 24 cases with various spinal disorders were treated in our department using the Dick technique. The results were as follows: In the fresh fracture group (7 cases), all the spine fractures were reduced anatomically: the 2 cases without neurological defects returned to work 3 months after operation; the 3 cases with incomplete paraplegia had rapid neurological recovery; and the 2 cases with complete paraplegia showed no recovery after operation. In the late fracture group (10 cases), traumatic kyphotic curves were partially reduced and back pain was decreased markedly in all: Muscle power was increased significantly in 3 cases; spasticity was remarkably improved in 2 cases; 3 cases obtained complete cure of incontinence; and 4 cases had no significant improvement. In 3 cases with ankylosing spondylitis, the initial average kyphotic curve was 73.3 degrees, while the postoperative average curve was 28.3 degrees. The result of treatment of spinal stenosis due to degenerative spondylolisthesis (1 case) was good; slipping vertebrae were stabilized and fused with the Dick system after thorough decompression. In 1 tumor and 2 Tb-spine cases, the patients recovered and were ambulatory soon after operation.
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PMID:The application of Dick instrumentation in spine surgery. 142 57

We report an unusual case of spinal fracture in ankylosing spondylitis. The fracture occurred through the S1 vertebral body and resembled a traumatic spondylolisthesis. Treatment consisted of prompt operative intervention after extensive diagnostic evaluation. The case emphasizes the difficulty of diagnosing spinal fractures in those with ankylosing spondylitis, the necessity for being alert to the possibility of fracture in this group, and the value of early surgical intervention for sacral fractures with neural deficit.
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PMID:Fracture of the S1 vertebral body in a patient with ankylosing spondylitis. 160 83

X-ray examinations of the lumbar spine from a two-year period in 268 Greenlanders and an equivalent number of danes were reviewed in order to diagnose all radiological lesions. Twenty-five percent of the X-ray examinations of the Greenlanders and 28% of the Danes showed normal conditions. Eighteen percent of the Greenlanders and 3% of the Danes had evident sacroliitis. Four Greenlanders and one Dane had radiological ankylosing spondylitis. The high frequency of sacroiliitis can probably be explained by the genetic structure of the population and the pattern of infections. Spondylolisthesis was found in 24% of the Greenlanders, confirming previous findings. Degenerative lesions, fractures, developmental anomalies and Scheuermann's disease were equally frequent in the two populations, while scolioses were less frequent among the Greenlanders than among the Danes.
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PMID:[Radiographic examination of the lumbar spine in Greenlanders]. 221 88

Fractures of the axis organ in ankylosing spondylitis display special features resulting from the peculiar underlying osteopathy. Depending on the localisation und extent of the vertebral ossification process, the mechanical load situations are different from case to case. Besides the disease-specific metaplastic-productive development, it is also possible that the peculiar destructive-absorptive component dominates in the overall pattern of the fracture, leading to false interpretations such as "non-typical fracture", "persistent pseudoarthrosis", specific spondylitis, stress fracture, suspected tumour, etc. Eight observations by the author demonstrate the risks, problems, differential diagnostic difficulties and the experience collected from observations of the course of the disease: four fractures of the cervical vertebral column (following mild traumas) were mainly flexion, luxation (compression) fractures at C 5/6 with partly extensive spondylodiscitic destruction, conservative treatment being sufficient in the absence of severe neurological symptoms (with one exception). A transvertebral fracture (after trauma) had occurred at the eleventh thoracic vertebral body with extremely protracted healing. Two stress fractures in which healing tendency was absent, were seen in a lumbar vertebral column sigment with spondylo-arthritically stiffened vertebral arch components, being probably a post-traumatic spondylolisthesis in segment L 5/S 1.
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PMID:[Fractures of the axis organ in ankylosing spondylitis (author's transl)]. 741 29

From June, 1989 to March, 1991, 24 cases were treated in our department with the Dick technique. The study population included 7 patients with fresh horacolumber spine fracture, 10 with late spinal fracture (15 of the above 17 cases had incomplete paraplegia), 3 with ankylosing spondylitis, 2 with tuberculosis, and one each with spondylolisthesis and spine tumor. The results of these 24 cases were as follows. In the fresh fracture group, all the spine fractures were reduced completely. The 2 patients without neurological defects returned to work 3 months after operation. The 3 with incomplete paraplegia had rapid neurological recovery and could walk with a brace 3 months after surgical treatment. The 2 with complete paraplegia did not recover after toperation. In the late fracture group, traumatic kyphotic curve were reduced partially and back pain was decreased markedly in all 10 cases. Muscular power was increased significantly in 3 cases; they are all able to walk with a cane. Spasticity was remarkably improved in 2 patients after operation; they can now walk with crutches. Three patients obtained complete cure of incontinence. Four patients had no significant improvement. In the 3 patients with ankylosing spondylitis, the initial average kyphotic curve was 73.3 degrees, while the postoperative average curve was 28.3 degrees. The result in treating spinal stenosis due to degenerative spondylolisthesis was good: the slipping vertebrae were stabilized and fused with the Dick system after thorough decompression. In the tumor and Tb-spine cases, the patients recovered and were ambulatory soon after operation, thanks to rigid internal fixation.
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PMID:[The application of Dick instrumentation in the field of spine surgery]. 832 36

This article examines cervical deformities and their treatments, such as iatrogenic deformities, posttraumatic deformities, ankylosing spondylitis, rheumatoid arthritis, degenerative subaxial spondylolisthesis, myopathy, infectious spondylitis, and tumors. Congenital scoliosis and kyphosis and torticollis and rotatory atlanto-axial subluxation also are discussed.
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PMID:Cervical deformity: rationale for selecting the appropriate fusion technique (anterior, posterior, and 360 degree). 975 71

Nonphysiologic hyperextension and lateral forces acting on the cervical spine and soft-tissue structures of the neck can result in a wide spectrum of injury patterns. Multiple factors (eg, patient age; the underlying morphologic features of the cervical spine; the magnitude, vector, and maximal focus of the force) all influence the observed patterns and the severity of injury. A review of the 5-year trauma database in two trauma centers revealed various injury patterns that were frequently recognized in patients with clinical evidence or historical documentation of a predominant hyperextension mechanism. Injuries included anterior arch avulsion and posterior arch compression fractures of the atlas, odontoid fractures, traumatic spondylolisthesis and teardrop fracture of C2, laminar and articular pillar fractures, and hyperextension dislocation injuries. More severe injuries were observed in patients with underlying predisposing conditions (eg, degenerative spondylosis, ankylosing spondylitis, diffuse idiopathic skeletal hyperostosis). Knowledge of the involved biomechanical factors provides a framework for understanding these injury patterns. Diagnostic imaging, especially computed tomography and magnetic resonance imaging, plays a fundamental role in the assessment of patients with suspected cervical injury. Furthermore, cross-sectional imaging facilitates the recognition of accompanying injuries to the face, the head, and the vascular structures of the neck.
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PMID:Spectrum of imaging findings in hyperextension injuries of the neck. 1616 Jan 9

Computed tomography image-guided surgery (CTGS) clearly improves the accuracy of pedicle screw insertion. Recent reports claim that a fluoroscopy-guided system (FGS) offered high accuracy and easy application. However, the superiority of either technique remains unclear in clinical application. This study compares the accuracy of pedicle screws installed using CTGS with that of screws installed using FGS. Seventy-four screws inserted using FGS in 13 patients and 76 screws inserted using CTGS in 11 patients were compared. The study population included ten cases of vertebral fracture, five cases of degenerative spondylolisthesis, three cases of spondylolytic spondylolisthesis, two cases of tuberculous spondylitis, two cases of failed earlier back surgery and two case of ankylosing spondylitis with pseudarthrosis. The installed vertebral levels ranged from T8 to S1. Screw positions were assessed with postoperative radiographs and computed tomography. Sixty-nine (93.2%) screws were correctly placed in the FGS group, and seventy-three (96.1%) screws were correctly placed in the CTGS group (P=0.491). The results indicated that both image-guided systems offer high accuracy. However, the fluoroscope image-guided system could be considered the primary tool for lower thoracic and lumbosacral pedicle placement because it enables real-time navigation and does not require a preoperative CT scan.
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PMID:Pedicle screw insertion: computed tomography versus fluoroscopic image guidance. 1741 Mar 63