Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P01889 (ankylosing spondylitis)
 5,717 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case of Crohn's disease involving the stomach and duodenum is presented. The patient had a four-and-a-half year history of ankylosing spondylitis. Double contrast radiography of the stomach and duodenum showed multiple superficial gastric erosions and a duodenal ulcer. There were typical changes of Crohn's disease in the terminal ileum. At endoscopy, numerous superficial erosions were seen in the stomach and duodenum and biopsies of the stomach showed granulomatous inflammation, consistent with Crohn's disease. These lesions are similar to those seen in the colon in the early stages of granulomatous colitis and it is likely that this represents the early stage of Crohn's disease in the stomach. With increasing application of double-contrast radiography and endoscopy, these lesions may be found more frequently.
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PMID:Multiple superficial gastric erosions due to Crohn's disease of the stomach. Radiologic and endoscopic diagnosis. 95 93

A retrospective investigation of the prescription of nonsteroidal antiinflammatory drugs (NSA) was performed in the Rheumatologic out-patient-institute in Zagreb, including 1000 patients of both sexes, aged 20-70 years. 500 outpatients were treated by NSA during 1987 and 1989 respectively for lumbosacral syndrome, rheumatoid arthritis, ankylosing spondylitis and coxarthrosis. The kind of NSA as well as the registered side-effects were analysed from case histories. During 1987, NSA were applied to 365 (73%) and during 1989 to 390 (78%) of the 500 patients. In both groups a phenyl-acetic acid derivative (diclophenac) was most often applied, followed by propionic acid derivatives and oxycams. The most rarely applied drugs were indol-acetic acid derivatives. Pyrazolones were given only to 2 patients with an acute flare of ankylosing spondylitis in 1987. A gastro-duodenal ulcer was the absolute counterindication for this kind of treatment. The number of side-effects in this investigation was relatively small (6.5% in 1987 and 5% in 1989), probably because this investigation was a retrospective one. The most common among them appeared in the gastro-intestinal tract.
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PMID:[Use of non-steroidal antiinflammatory drugs in specialty polyclinic practice]. 249 3

The authors are presenting the case of a 53 year-old patient, suffering from type II diabetes mellitus and ankylosing spondylitis, admitted in our clinic in July 1997 for gastrojejunocolic fistula, 5 years after a transmesocolic gastrojejunostomy for obstructive chronic duodenal ulcer. The severe metabolic disorders and the radiologic aspects which led to the diagnosis, as well as the morphopathologic lesions found and the ways to approach the fistula, the stenotic duodenal ulcer and the reconstruction of the digestive continuity in a single surgical procedure are further discussed. The conclusions are shown at the end.
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PMID:[Gastrojejunocolic fistula after transmesocolic gastrojejunostomy for stenotic duodenal ulcer]. 1495 46