Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P01889 (
ankylosing spondylitis
)
5,717
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A patient presented with typical features of
ankylosing spondylitis
, as well as some of the biochemical abnormalities expected in this disease. In addition the patient had symptoms and signs of biventricular heart failure (
dilated cardiomyopathy
) with conduction defect. No valve lesions were demonstrated. A non-reducible head tilt, seldom described in
ankylosing spondylitis
, was also present. A short review of the possible mechanisms in the development of
dilated cardiomyopathy
in
ankylosing spondylitis
is given.
...
PMID:[Dilated cardiomyopathy in a patient with ankylosing spondylitis. A case report]. 341 15
A 58 years old male with a long-standing history of HLA-B27 positive
ankylosing spondylitis
presented with increasing fatigue and dyspnea on exertion. He had left ventricular dysfunction and enlargement, flail right coronary leaflet of aortic valve with severe eccentric aortic insufficiency along with left ventricular non-compaction in echocardiography. The most common cardiac manifestations of
ankylosing spondylitis
are aortic insufficiency and conduction disturbances. Involvement of myocardium, in the form of
dilated cardiomyopathy
and restrictive cardiomyopathy, has also been reported. This case presents a very rare association of
ankylosing spondylitis
with non-compaction cardiomyopathy.
...
PMID:Left ventricular non-compaction in a patient with ankylosing. 2821 Apr 76
