Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P01350 (
gastrin
)
9,683
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
gastrin
9683
somatostatin
1776
cholecystokinin
1463
insulin
1098
glucagon
912
secretin
837
bombesin
670
pancreatic polypeptide
634
Sep
587
CCK
583
gut
551
CCK-B receptor
450
polypeptide
361
motilin
358
calcitonin
354
substance P
346
neurotensin
338
pepsinogen
266
proton pump
254
vasoactive intestinal peptide
222
chromogranin A
189
Mol
173
ECL
170
gastrin-releasing peptide
169
histidine decarboxylase
163
gastric inhibitory polypeptide
158
amylase
144
vasoactive intestinal peptide (VIP)
143
beta-endorphin
140
CCK-B
139
growth hormone
139
VIP
137
ATPase
130
CCK-A
129
ACTH
126
peptide YY
126
epidermal growth factor
115
G17
107
ghrelin
101
neuron-specific enolase
101
Met
97
prolactin
94
neuropeptide Y
92
GIP
88
CCK8
73
SRIF
73
GRP
73
synaptophysin
72
AMP
72
adenylate cyclase
67
parathyroid hormone
64
oxytocin
62
peroxidase
61
galanin
61
mucin
61
vasopressin
60
CCK-4
59
tRNA
58
AGS
56
SMS
55
chronic renal failure
55
EGF
55
5-hydroxytryptamine
55
somatostatin receptor
53
neuromedin B
48
dynorphin
46
intrinsic factor
45
ZES
42
B12
40
lipase
40
adrenocorticotropic hormone
39
She
39
carcinoembryonic antigen
38
Gen
37
albumin
36
tyrosine kinase
36
gastrointestinal peptide
34
GHRH
33
ATP
33
cyclooxygenase-2
32
ornithine decarboxylase
32
cytokine
32
Pol
31
alkaline phosphatase
31
Ghrelin
30
PTH
30
leptin
30
Calcitonin
30
glycoprotein
30
NSE
29
serum albumin
29
COX-2
29
kit
29
Sp1
28
enolase
28
endoplasmic reticulum
28
mast cell
28
Met-enkephalin
27
MEC
27
GAS
27
GLP-1
26
pepsinogen A
26
pituitary adenylate cyclase-activating polypeptide
26
parathormone
26
glucose-dependent insulinotropic polypeptide
25
muscarinic receptor
25
c-fos
25
PKC
25
PAO
24
CEA
24
GTP
24
NMR
24
Boc
24
cyclooxygenase
23
casein
23
chorionic gonadotropin
23
bradykinin
23
PGA
23
angiotensin II
23
cytokeratin
23
Epidermal growth factor
23
pepsinogen C
22
EGF receptor
22
tumor necrosis factor
22
ERK1
22
phosphodiesterase
22
GABA
21
chymotrypsin
21
transferrin
21
p53
21
TRH
21
histamine H2 receptor
21
proinsulin
21
amylin
21
vesicular monoamine transporter 2
20
nitric oxide synthase
20
colon carcinoma
20
Nle
20
acetylcholinesterase
20
lysozyme
20
CgA
20
corticotropin-releasing factor
20
collagenase
20
renin
19
PAP
19
Vasoactive intestinal peptide
19
collagen
19
Ki-67
19
Pepsinogen
19
membrane-bound
19
Histidine decarboxylase
19
membrane protein
19
MAPK
19
ERK
19
CGRP
18
PRL
18
TNF
18
IL-8
18
hemoglobin
18
COX-1
18
more...
Disease
tumor
1053
duodenal ulcer
689
cancer
629
Zollinger-Ellison syndrome
555
gastrinoma
384
gastritis
370
peptic ulcer
352
atrophic gastritis
304
carcinoid
289
carcinoma
266
gastric cancer
242
metastases
217
multiple endocrine neoplasia
198
gastric ulcer
181
adenocarcinoma
177
carcinogenesis
161
pernicious anemia
145
diabetes
134
hypoglycemia
120
gastroesophageal reflux disease
111
Helicobacter pylori infection
111
SEM
103
colon cancer
85
hyperparathyroidism
80
chronic renal failure
74
tumor growth
73
dysplasia
71
dyspepsia
68
colorectal cancer
67
pancreatic cancer
66
MEN1
66
neuroendocrine tumor
65
esophagitis
64
insulinoma
62
adenoma
62
hypercalcemia
61
liver metastases
61
medullary thyroid carcinoma
60
small cell lung cancer
60
AGS
56
SMS
55
celiac disease
49
primary hyperparathyroidism
48
lung cancer
48
obesity
48
Pancreas
45
Pancreas
45
anemia
42
cirrhosis
40
hyperglycemia
37
cold
37
depression
37
glucagonoma
35
tumorigenesis
35
lung carcinoma
33
Barrett's esophagus
33
carcinoid syndrome
32
reflux esophagitis
31
pertussis
30
prostate cancer
29
type 2 diabetes
29
malabsorption
29
acromegaly
28
renal failure
28
chronic pancreatitis
28
hyperinsulinemia
27
glioblastoma
26
hypertension
26
primary tumor
25
glioma
23
tumor progression
23
pancreatic gastrinoma
23
neuroendocrine carcinoma
23
H pylori infection
22
somatostatinoma
22
islet cell carcinoma
22
cholera
22
infectious diseases
21
Cushing's syndrome
21
gallstones
21
breast cancer
21
gastrointestinal disease
20
duodenitis
20
Infection
20
G cell hyperplasia
19
INS
18
glucose intolerance
18
Best
18
Helicobacter pylori gastritis
18
malnutrition
18
hyperthyroidism
17
type 1 diabetes
17
worms
17
stress ulcer
17
pituitary tumor
16
lymphoma
16
SDS
16
rheumatoid arthritis
15
pancreatitis
15
ischemia
15
Gastric Cancer
15
Crohn's disease
15
WDHA syndrome
15
neoplastic transformation
14
pheochromocytoma
14
Stomach
14
Stomach
13
hypothyroidism
13
aggression
13
irritable bowel syndrome
13
short bowel syndrome
13
Stomach
13
iron deficiency anemia
13
achalasia
13
gastrointestinal cancer
13
Stomach
13
uremia
12
hyperprolactinemia
12
hyperphagia
12
pituitary adenoma
12
acute pancreatitis
12
vitamin B12 deficiency
12
leukemia
12
Esophageal
12
Pineal
11
megaloblastic anemia
11
uterus
11
steatorrhea
11
tuberculosis
11
renal disease
10
alcoholism
10
pruritus
10
Luminal
10
gastric mucosal atrophy
10
HCG
10
non-small cell lung cancer
10
pancreatic insufficiency
10
cystic fibrosis
10
renal insufficiency
10
macrocytic anemia
10
drug withdrawal
10
paraganglioma
9
mucosa-associated lymphoid tissue
9
mastocytosis
9
autonomic neuropathy
9
neuroblastoma
9
Hyperplasia
9
influenza
9
esophageal cancer
9
perforated duodenal ulcer
9
hiatal hernia
9
gastroparesis
9
rare disease
9
BPP
9
Chagas
9
Graves' disease
9
peritonitis
9
iron deficiency
8
neurofibromatosis
8
neurofibromatosis type 1
8
more...
Symptom
acidity
235
diarrhea
211
vomiting
60
abdominal pain
59
pain
51
starvation
38
anesthesia
34
constipation
34
nausea
31
anorexia
28
heartburn
24
epigastric pain
19
hunger
15
flushing
14
nausea and vomiting
13
fatigue
12
erythema
10
headache
9
discomfort
7
overweight
7
weakness
7
discomfort
7
bloating
6
analgesia
6
regurgitation
6
Wind
5
hypothermia
5
abdominal discomfort
5
Gastrointestinal symptoms
5
dizziness
4
belching
4
colic
4
cachexia
4
dysuria
3
paresis
3
hepatomegaly
3
abdominal cramps
3
tense
3
chronic constipation
2
intestinal bleeding
2
blurred vision
2
angina
2
respiratory distress
2
arthralgia
2
asthenia
2
seizures
2
myalgia
2
retching
2
hypoproteinemia
2
back pain
2
thinning
2
ataxia
2
low back pain
2
chest pain
2
decreased appetite
2
lethargy
2
Welt
2
vertigo
2
splenomegaly
2
exertional dyspnea
1
Peptic ulcer symptoms
1
dysesthesia
1
sleepiness
1
hyperemesis
1
Bilious vomiting
1
pallor
1
Ill
1
bitter taste
1
syncope
1
emaciation
1
abdominal fullness
1
Cushingoid
1
stomach distension
1
tremor
1
collapse
1
distraction
1
insomnia
1
hemoptysis
1
astasia
1
leg edema
1
Gurgling
1
acute abdomen
1
No pain
1
bone pain
1
Burning pain
1
Bladder distention
1
ACHE
1
catarrh
1
Cushingoid
1
wheezing
1
mastalgia
1
right lower quadrant pain
1
cerebellar ataxia
1
polydipsia
1
Scratch
1
Mucosal hyperplasia
1
agitation
1
exhaustion
1
spasm
1
stomach pain
1
general problem
1
hypotonia
1
adipsia
1
night sweats
1
shortness of breath
1
clubbing
1
Drug
Histamine
125
Omeprazole
106
Secretin
95
Atropine
89
Glucagon
68
Cimetidine
54
Cimetidine
53
Gel
47
Proglumide
38
PTH
32
lysine
28
Ranitidine
26
Asn
22
Indomethacin
21
Gastro
19
Enprostil
17
Portal
16
Nephron
16
caffeine
15
Ethanol
14
GRF
12
CaCl2
11
Forskolin
11
CaCl2
11
CaCl2
11
HCG
10
Gastrin I
10
Histalog
10
Loxiglumide
10
Histalog
10
ENT
9
Sandostatin
9
Sandostatin
9
CAM
8
MTC
8
Growth hormone
7
Dial
7
Nephron
7
Biopolymers
7
Bisacodyl
6
Growth hormone
6
Paraffin
6
Vitamin B12
6
Tetragastrin
6
Misoprostol
6
ETA
6
ascorbate
6
Ciprofibrate
5
MAP
5
Cobalamin
5
OctreoScan
5
MEA
5
ICI
4
Monit
4
Apomorphine
4
Rioprostil
4
BTC
4
Dermatol
4
Peptavlon
4
IFN-gamma
4
Cardiovasc
4
IL-2
3
Scopolamine
3
Leaf
3
Fluorescein
3
Maalox
3
Domperidone
3
Orion
3
Pitressin
3
Cisapride
3
Alanine
3
Sandostatin LAR
3
Calcium gluconate
3
Ranitidine hydrochloride
3
EE2
3
Luteinizing
2
ADR
2
DNase I
2
Angiotensin II
2
Tiotidine
2
Retinoic acid
2
L 364718
2
Captopril
2
Vioxx
2
niacin
2
ADM
2
Wine
2
Indapamide
2
Theophylline
2
Sodium nitroprusside
2
Ammonium chloride
2
Atropine sulfate
2
PFT
2
ALA
2
Reserpine
2
CER
2
Sulpiride
2
Medetomidine
2
CSF
2
AGG
2
Orphan
2
ZnCl2
2
Carbenoxolone
2
ZnCl2
2
Diphenhydramine
2
Ranitidine bismuth citrate
1
Magnesium trisilicate
1
Edrophonium chloride
1
Midostaurin
1
Fructose
1
Lapaquistat acetate
1
Regadenoson
1
Dakar
1
Gelatin
1
balanced salt solution
1
Guanethidine
1
Enprofylline
1
Aprotinin
1
Rilonacept
1
Primperan
1
Estriol
1
Fluorescein
1
NAG
1
Monosodium glutamate
1
AMC
1
Ouabain
1
Ecabet sodium
1
IL-11
1
Riopan
1
Lutalyse
1
Metoclopramide hydrochloride
1
Exenatide
1
Motexafin gadolinium
1
Forodesine hydrochloride
1
Orlistat
1
uPA
1
Phentolamine
1
Itopride hydrochloride
1
Ferumoxytol
1
MRC
1
Dronedarone hydrochloride
1
Lioresal
1
ROC
1
Rolipram
1
Papaverine
1
VCR
1
CTT
1
Spectrum
1
Nitric Oxide
1
nitroglycerin
1
Salbutamol
1
Dextrose
1
Hoelen
1
Adenosine triphosphate
1
Zosuquidar trihydrochloride
1
Adriamycin
1
Imatinib
1
Tipifarnib
1
Vitamin E
1
Epigallocatechin
1
more...
Enzyme
pepsin
264
histidine decarboxylase
175
ATPase
144
protein kinase C
91
trypsin
89
mitogen-activated protein kinase
72
adenylate cyclase
71
peroxidase
67
ERK
63
protein kinase
57
lipase
40
urease
40
urease
39
luciferase
39
phospholipase C
37
ornithine decarboxylase
32
alkaline phosphatase
31
monoamine oxidase
28
enolase
28
acetylcholinesterase
27
GAS
27
reverse transcriptase
26
focal adhesion kinase
25
collagenase
24
phosphodiesterase
22
MEK
22
lysozyme
20
chymotrypsin
20
renin
19
carbonic anhydrase
17
catalase
17
invertase
17
CD10
16
sucrase
15
alanine aminotransferase
14
lactase
14
RNA polymerase
13
caspase-3
12
RNase
12
RNase
11
alpha-glucosidase
11
diamine oxidase
10
alpha-amylase
9
phosphatidylinositol 3-kinase
9
NO synthase
9
tyrosine hydroxylase
9
ACE
8
phenylalanyl-tRNA synthetase
8
NOS
8
superoxide dismutase
8
carboxypeptidase E
8
AMPK
8
guanylate cyclase
7
calcineurin
7
lactate dehydrogenase
7
PAM
7
urokinase-type plasminogen activator
7
thymidine kinase
7
carboxypeptidase B
7
cholinesterase
7
aspartate aminotransferase
6
S1 nuclease
6
endonuclease
6
H,K-ATPase
6
alcohol dehydrogenase
5
MAP
5
TGT
5
glutamate decarboxylase
5
APC
5
furin
5
DNase
5
transcriptase
5
sulfatase
5
ECH
4
aspartyl-tRNA synthetase
4
proteasome
4
meprin
4
tryptase
4
DOPA decarboxylase
4
succinate dehydrogenase
4
arylsulfatase
4
acid phosphatase
4
3-hydroxyacyl-CoA dehydrogenase
3
CD13
3
kallikrein
3
ADH
3
aromatic L-amino acid decarboxylase
3
phospholipase A2
3
caspase-9
3
astacin
3
myosin light chain kinase
3
MMP-3
3
ribonuclease
3
aequorin
3
cathepsin D
3
gastricsin
3
subtilisin
3
3-hydroxyacyl-CoA dehydrogenase
3
ribonuclease
3
prostate-specific antigen
3
beta-galactosidase
3
ACS
3
succinic dehydrogenase
3
chloramphenicol acetyltransferase
3
leucine aminopeptidase
3
prostate-specific membrane antigen
3
cathepsin B
2
aldehyde dehydrogenase
2
aldehyde dehydrogenase
2
sucrase-isomaltase
2
penicillin binding protein
2
glutathione peroxidase
2
aldehyde dehydrogenase
2
phosphofructokinase
2
glyceraldehyde-3-phosphate dehydrogenase
2
cytochrome oxidase
2
aldehyde dehydrogenase
2
aldehyde dehydrogenase
2
CaMKII
2
histamine N-methyltransferase
2
ceruloplasmin
2
gamma-glutamyl transpeptidase
2
citrate synthase
2
carboxypeptidase Y
2
thrombin
2
5'-nucleotidase
2
chymosin
2
firefly luciferase
2
choline acetyltransferase
2
proprotein convertase
2
P-glycoprotein
2
sorbitol dehydrogenase
2
malate dehydrogenase
2
phosphoinositide 3-kinase
2
creatine kinase
2
thymidylate synthase
2
ALA synthase
2
neuraminidase
2
dipeptidyl peptidase IV
2
phospholipase D
2
CYP3A4
2
SST
2
PAL
2
RNA ligase
2
PARP
1
cathepsin G
1
ADP-ribosyltransferase
1
papain
1
methylmalonyl-CoA mutase
1
thyroid peroxidase
1
ADP-ribosyltransferase
1
fumarase
1
cathepsin S
1
glyceraldehyde-3-phosphate dehydrogenase
1
prolyl endopeptidase
1
dextranase
1
methionine synthase
1
pyruvate dehydrogenase
1
methionyl-tRNA synthetase
1
KAT
1
more...
Compound
Dec
675
Clin
656
calcium
562
glucose
472
DNA
311
tyrosine
238
water
234
Gly
151
Phe
150
methionine
148
sodium
141
NH2
134
arginine
132
cAMP
129
ACTH
128
Histamine
125
leucine
119
HCl
113
Omeprazole
111
Asp
111
ethanol
109
G17
107
His
105
5-HT
103
Pentagastrin
103
Secretin
97
Atropine
89
alanine
77
AMP
75
galactose
72
phosphate
72
Insulin
69
hydrogen
68
Glucagon
68
urea
67
sulfate
60
acetate
57
acetic acid
56
silver
55
lysine
54
noradrenaline
54
nitric oxide
53
potassium
52
PGE2
51
tryptophan
49
cGMP
47
oxygen
47
tryptophan
44
tryptophan
44
tryptophan
44
iron
42
salt
40
threonine
40
Substance P
39
Carbachol
36
Ile
35
ATP
33
cysteine
31
ammonia
31
serine
30
Calcitonin
30
TSH
30
creatinine
28
isoleucine
28
PGE
28
isoleucine
28
prostaglandin E1
28
COS
28
PEG
27
phosphorus
27
TRH
27
ACh
26
formaldehyde
25
GABA
25
GTP
25
Octreotide
25
EDTA
24
GABA
24
EDTA
24
glutamic acid
24
Pirenzepine
24
Neurotensin
23
Ranitidine
23
bromide
23
glutamate
22
zinc
22
formaldehyde
22
carbonate
21
Indomethacin
21
barium
20
PAP
19
PAP
19
PAP
19
aldosterone
19
PAP
19
aspartic acid
18
iodine
18
TNF
18
Mg2+
18
nitrogen
18
SO3
17
SDS
16
glycerol
16
gamma-aminobutyric acid
16
Naloxone
16
aspartic acid
16
CO2
16
Isoproterenol
15
MK-329
15
Cysteamine
15
aspartic acid
15
PEG
15
aspartic acid
15
caffeine
15
MEK
14
ammonium
14
DTPA
14
vitamin D
14
Diabetol
13
Melatonin
13
proline
13
Metiamide
12
MTT
12
copper
12
Methacholine
12
norleucine
12
sodium chloride
12
Lansoprazole
12
aluminum
12
norleucine
12
Forskolin
11
hydroxide
11
aldehyde
11
Propranolol
11
DEAE
11
CaCl2
11
Propranolol
11
Luminal
10
trifluoroacetic acid
10
trifluoroacetic acid
10
Adrenal
10
Dopamine
10
glutamine
10
trifluoroacetic acid
10
5-HIAA
10
trifluoroacetic acid
10
trifluoroacetic acid
10
methylhistamine
9
ornithine
9
Trypsin
9
valine
9
MDA
9
alpha-MSH
9
Norepinephrine
9
ornithine
9
ornithine
9
aldehyde
9
Tyrosine
9
methanol
9
STZ
9
more...