Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P01350 (gastrin)
 9,683 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The correlation between intestinal resorption and changes in hormone (gastrin, insulin, triiodothyronine, ACTH and cortisol) and cyclic nucleotide secretion was examined in 53 patients with chronic enteritis. Blood hormone and cyclic nucleotide levels were measured by radioimmunoassay. Intestinal activity was assessed by combined diagnostic tests. Most patients with impaired small-intestinal resorption showed considerable changes in hormonal and cyclic nucleotide levels. Abnormal operation of the hormone-cyclase system may be related to changed levels of both the hormones and cyclic nucleotides. The results of the study may be useful for the understanding of the pathogenesis as well as the diagnosis of intestinal resorption disorders in patients with chronic enteritis.
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PMID:[The hormone-cyclase system and its possible role in disorders of the absorptive function of the intestines]. 272 83

A study was made of changes of the content of hormones (gastrin, insulin, glucagon, triodonthyronine, thyroxine, thyrotrophin, somatotrophin, adrenocorticotrophin and hydrocortisone) under the influence of standard food load in 166 patients with GIT diseases (gastric ulcer, duodenal ulcer, chronic anacid gastritis and chronic enteritis). Forty-three healthy persons entered the control group. Hormones were determined in the peripheral blood by radioimmunoassay. Taking food in healthy persons was shown to cause the stimulation of the secretion of most hormones. To elucidate the mechanisms of hormonal shifts after food load, hormones were also studied after per os intake of solutions with different pH. Disorders of postprandial reactions of the endocrine system which were specific for these nosological forms, were revealed in GIT diseases. The results of the study are of interest in view of new approaches to functional interrelationships of the GIT with endocrine glands.
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PMID:[New approaches to studying the functional relations of the gastrointestinal tract with the endocrine glands]. 408 61