Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P01275 (
glucagon
)
26,492
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
glucagon
26492
insulin
15833
somatostatin
3261
Sep
1740
gut
1665
GLP-1 receptor
1605
growth hormone
1394
pancreatic polypeptide
1227
GLP-1
1202
peptidase
1023
AMP
1002
gastrin
912
secretin
900
Mol
845
adenylate cyclase
800
cholecystokinin
765
polypeptide
648
glucose-dependent insulinotropic polypeptide
619
DPP
586
ATP
570
ghrelin
551
leptin
534
glucagon receptor
513
peptide YY
498
vasopressin
472
calcitonin
419
hemoglobin
390
amylin
344
vasoactive intestinal peptide
338
gastric inhibitory polypeptide
329
GLP
328
dipeptidyl peptidase IV
323
ACTH
319
beta-endorphin
306
neurotensin
306
albumin
291
prolactin
270
proinsulin
262
phosphoenolpyruvate carboxykinase
244
GIP
237
substance P
236
phosphodiesterase
235
vasoactive intestinal peptide (VIP)
228
adenylyl cyclase
223
SRIF
221
amylase
221
CCK
214
bombesin
211
glucokinase
205
VIP
204
parathyroid hormone
199
GTP
194
neuropeptide Y
182
pituitary adenylate cyclase-activating polypeptide
180
Gen
180
insulin receptor
180
epidermal growth factor
176
angiotensin II
171
endoplasmic reticulum
167
pyruvate kinase
165
motilin
165
cytokine
163
collagenase
159
glycogen phosphorylase
157
glucose transporter
156
GHRH
154
oxytocin
151
INS-1
140
chromogranin A
140
adiponectin
138
G protein-coupled receptor
136
ADP
134
renin
133
collagen
131
glucose-6-phosphatase
130
PKA
129
PDX-1
126
casein
123
serum albumin
120
glycogen synthase
120
more...
Disease
diabetes
5794
type 2 diabetes
3025
hypoglycemia
2325
hyperglycemia
1822
obesity
1417
tumor
741
hyperinsulinemia
640
glucose intolerance
623
type 1 diabetes
618
cancer
332
insulinoma
316
SEM
257
cardiovascular disease
257
glucagonoma
255
cirrhosis
221
hypertension
212
Alzheimer's disease
203
metabolic syndrome
191
depression
181
fatty liver
176
heart failure
164
pancreatitis
155
stroke
148
pertussis
146
cold
146
Pancreas
144
hepatocellular carcinoma
140
Pancreas
140
ischemia
132
carcinoma
128
ketosis
125
chronic pancreatitis
122
hyperlipidemia
118
cholera
112
metastases
112
short bowel syndrome
108
myocardial infarction
106
atherosclerosis
103
sepsis
102
diabetic ketoacidosis
100
sepsis
100
acute pancreatitis
99
dyslipidemia
98
hyperphagia
96
liver disease
93
renal disease
90
carcinoid
85
multiple endocrine neoplasia
83
Parkinson's disease
81
malnutrition
76
SDS
73
chronic renal failure
72
malabsorption
67
anemia
65
acromegaly
63
adenocarcinoma
62
alcoholic fatty liver
60
diabetic nephropathy
59
renal failure
58
pheochromocytoma
58
neuropathy
56
SMS
56
cognitive impairment
55
Pituitary
55
pancreatic cancer
54
celiac disease
53
hypothyroidism
53
INS
53
uremia
52
portal hypertension
51
prediabetes
51
autonomic neuropathy
51
coma
50
hyperthyroidism
48
osteoporosis
48
metabolic disorder
47
retinopathy
46
gestational diabetes mellitus
45
GSH
45
adenoma
44
more...
Symptom
starvation
273
hunger
175
overweight
172
anesthesia
150
nausea
143
diarrhea
135
anorexia
99
erythema
93
vomiting
85
pain
75
exhaustion
61
seizures
59
fatigue
45
ketonuria
34
hypothermia
34
cachexia
33
nausea and vomiting
32
discomfort
30
discomfort
30
hepatomegaly
30
weakness
28
abdominal pain
28
headache
24
constipation
22
polyuria
22
spasm
21
polydipsia
20
analgesia
19
collapse
19
acute stress
18
Ill
15
angina
14
lethargy
14
colic
14
tremor
13
flushing
12
functional recovery
10
dizziness
10
decreased appetite
10
hypotonia
10
bitter taste
8
respiratory distress
7
pallor
7
hypercapnia
6
agitation
6
hypoproteinemia
6
emaciation
6
epigastric pain
6
memory loss
5
sleepiness
5
acidity
5
HSA
5
bone pain
5
ataxia
5
ENT
4
dyspnea
4
hyperoxia
3
vertigo
3
regurgitation
3
acute pain
3
microbial colonization
3
autodigestion
3
thinning
3
stomach distension
3
blurred vision
3
splenomegaly
3
syncope
3
cyanosis
3
tonic-clonic seizure
3
asthenia
3
myalgia
2
wheezing
2
generalized rash
2
heartburn
2
tingling
2
enuresis
2
rhinorrhea
2
cough
2
paresis
2
paresthesia
2
more...
Drug
Glucagon
3742
Liraglutide
243
Exenatide
157
lysine
139
Secretin
117
Gel
103
Cardiovasc
92
Nephron
89
Growth hormone
88
Growth hormone
87
Portal
80
PTH
67
caffeine
54
NADH
53
Asn
52
Alanine
51
Forskolin
43
GRF
40
lactose
39
Phentolamine
34
Fructose
34
Atropine
33
Dermatol
31
Theophylline
31
Ethanol
31
Pramlintide
29
CTX
29
CPR
29
Angiotensin II
28
CTX
26
Teduglutide
26
CTX
26
Glycerol
24
ROS
22
Sandostatin
22
Sandostatin
22
Bifidobacterium
21
nitroglycerin
19
Albumin
18
ascorbate
17
IL-2
16
Activin
15
ENT
15
ICI
15
CaCl2
15
ADM
15
Histamine
14
MAP
14
Clonidine
14
CaCl2
14
GHRP
14
CSF
14
NH3
14
vitamin E
14
CaCl2
14
citric acid
13
Nephron
13
Aprotinin
13
Scopolamine
12
Monit
12
Ouabain
12
Diurnal
11
HCG
11
Humulin
11
Buscopan
11
Glutathione
10
IFN-gamma
10
DMI
10
DNase I
9
Rosiglitazone
9
NVP
9
Dial
9
Januvia
9
TAT
9
ROC
8
Galactose
8
Leaf
8
EPI
8
Indomethacin
8
Amiloride
7
more...
Enzyme
adenylate cyclase
854
protein kinase
702
phosphorylase
325
phosphoenolpyruvate carboxykinase
259
dipeptidyl peptidase IV
245
phosphodiesterase
240
phosphoenolpyruvate carboxykinase
239
phosphoenolpyruvate carboxykinase
236
mitogen-activated protein kinase
205
glucokinase
205
protein kinase C
193
AMPK
174
AMP-activated protein kinase
172
pyruvate kinase
165
collagenase
158
trypsin
139
renin
133
peroxidase
132
glucose-6-phosphatase
131
ATPase
105
lipase
103
ERK
98
caspase-3
86
alpha-glucosidase
82
tyrosine aminotransferase
79
phospholipase C
79
alkaline phosphatase
76
AMPK
75
tyrosine hydroxylase
70
catalase
68
alanine aminotransferase
63
pyruvate carboxylase
62
superoxide dismutase
61
lipoprotein lipase
60
phosphofructokinase
58
acetyl-CoA carboxylase
57
calcineurin
56
phosphorylase kinase
55
luciferase
53
lactate dehydrogenase
52
CPT
52
phosphatidylinositol 3-kinase
52
glucose-6-phosphate dehydrogenase
46
focal adhesion kinase
45
CD10
43
MEK
42
ornithine decarboxylase
41
aspartate aminotransferase
40
hexokinase
38
furin
37
chymotrypsin
37
CPR
36
glutathione peroxidase
34
reverse transcriptase
34
adenosine deaminase
33
adenosine deaminase
33
pyruvate dehydrogenase
32
sucrase
30
NO synthase
30
alcohol dehydrogenase
30
insulin-degrading enzyme
30
GSK
28
invertase
28
creatine kinase
27
hormone-sensitive lipase
27
fructose 1,6-bisphosphatase
27
ACS
26
pyruvate dehydrogenase
26
guanylate cyclase
26
pyruvate dehydrogenase
26
CPT
25
6-phosphofructo-2-kinase
25
elastase
25
RNase
24
chloramphenicol acetyltransferase
24
RNase
24
phosphoinositide 3-kinase
24
CPT
22
ACE
22
phospholipase A2
22
more...
Compound
glucose
12790
Glucagon
3742
Clin
2009
Dec
1851
Insulin
1835
cAMP
1591
arginine
1308
calcium
1249
AMP
1090
sodium
861
alanine
710
water
628
Pac
605
DPP
586
ATP
570
DNA
543
glycerol
533
oxygen
502
Diabetol
407
leucine
402
phosphate
382
urea
373
galactose
356
tyrosine
348
ACTH
318
noradrenaline
317
acetate
306
His
295
nitrogen
273
lysine
265
potassium
251
serine
225
glutamine
217
methionine
215
Phe
209
Adrenal
208
GTP
194
glutamate
193
ethanol
188
alloxan
181
Diabetol
178
Ile
178
threonine
161
NH2
161
sulfate
152
zinc
142
FFA
141
nitric oxide
140
tryptophan
138
ADP
137
tryptophan
135
isoleucine
135
cGMP
134
ADP
134
ADP
134
isoleucine
133
tryptophan
132
tryptophan
132
salt
126
creatinine
121
STZ
120
Secretin
117
5-HT
115
aldosterone
112
Gly
110
nicotinamide
109
Mg2+
108
prostaglandin E1
105
Asp
105
valine
105
CO2
101
TSH
100
proline
97
ammonia
95
TNF
93
NAD
87
Cortisol
86
Metformin
86
Metformin
85
Cardiol
84
more...