Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P01275 (glucagon)
26,492 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
glucagon 26492
insulin 15833
somatostatin 3261
Sep 1740
gut 1665
GLP-1 receptor 1605
growth hormone 1394
pancreatic polypeptide 1227
GLP-1 1202
peptidase 1023
AMP 1002
gastrin 912
secretin 900
Mol 845
adenylate cyclase 800
cholecystokinin 765
polypeptide 648
glucose-dependent insulinotropic polypeptide 619
DPP 586
ATP 570
ghrelin 551
leptin 534
glucagon receptor 513
peptide YY 498
vasopressin 472
calcitonin 419
hemoglobin 390
amylin 344
vasoactive intestinal peptide 338
gastric inhibitory polypeptide 329
GLP 328
dipeptidyl peptidase IV 323
ACTH 319
beta-endorphin 306
neurotensin 306
albumin 291
prolactin 270
proinsulin 262
phosphoenolpyruvate carboxykinase 244
GIP 237
substance P 236
phosphodiesterase 235
vasoactive intestinal peptide (VIP) 228
adenylyl cyclase 223
SRIF 221
amylase 221
CCK 214
bombesin 211
glucokinase 205
VIP 204
parathyroid hormone 199
GTP 194
neuropeptide Y 182
pituitary adenylate cyclase-activating polypeptide 180
Gen 180
insulin receptor 180
epidermal growth factor 176
angiotensin II 171
endoplasmic reticulum 167
pyruvate kinase 165
motilin 165
cytokine 163
collagenase 159
glycogen phosphorylase 157
glucose transporter 156
GHRH 154
oxytocin 151
INS-1 140
chromogranin A 140
adiponectin 138
G protein-coupled receptor 136
ADP 134
renin 133
collagen 131
glucose-6-phosphatase 130
PKA 129
PDX-1 126
casein 123
serum albumin 120
glycogen synthase 120
more...
Disease
diabetes 5794
type 2 diabetes 3025
hypoglycemia 2325
hyperglycemia 1822
obesity 1417
tumor 741
hyperinsulinemia 640
glucose intolerance 623
type 1 diabetes 618
cancer 332
insulinoma 316
SEM 257
cardiovascular disease 257
glucagonoma 255
cirrhosis 221
hypertension 212
Alzheimer's disease 203
metabolic syndrome 191
depression 181
fatty liver 176
heart failure 164
pancreatitis 155
stroke 148
pertussis 146
cold 146
Pancreas 144
hepatocellular carcinoma 140
Pancreas 140
ischemia 132
carcinoma 128
ketosis 125
chronic pancreatitis 122
hyperlipidemia 118
cholera 112
metastases 112
short bowel syndrome 108
myocardial infarction 106
atherosclerosis 103
sepsis 102
diabetic ketoacidosis 100
sepsis 100
acute pancreatitis 99
dyslipidemia 98
hyperphagia 96
liver disease 93
renal disease 90
carcinoid 85
multiple endocrine neoplasia 83
Parkinson's disease 81
malnutrition 76
SDS 73
chronic renal failure 72
malabsorption 67
anemia 65
acromegaly 63
adenocarcinoma 62
alcoholic fatty liver 60
diabetic nephropathy 59
renal failure 58
pheochromocytoma 58
neuropathy 56
SMS 56
cognitive impairment 55
Pituitary 55
pancreatic cancer 54
celiac disease 53
hypothyroidism 53
INS 53
uremia 52
portal hypertension 51
prediabetes 51
autonomic neuropathy 51
coma 50
hyperthyroidism 48
osteoporosis 48
metabolic disorder 47
retinopathy 46
gestational diabetes mellitus 45
GSH 45
adenoma 44
more...
Symptom
starvation 273
hunger 175
overweight 172
anesthesia 150
nausea 143
diarrhea 135
anorexia 99
erythema 93
vomiting 85
pain 75
exhaustion 61
seizures 59
fatigue 45
ketonuria 34
hypothermia 34
cachexia 33
nausea and vomiting 32
discomfort 30
discomfort 30
hepatomegaly 30
weakness 28
abdominal pain 28
headache 24
constipation 22
polyuria 22
spasm 21
polydipsia 20
analgesia 19
collapse 19
acute stress 18
Ill 15
angina 14
lethargy 14
colic 14
tremor 13
flushing 12
functional recovery 10
dizziness 10
decreased appetite 10
hypotonia 10
bitter taste 8
respiratory distress 7
pallor 7
hypercapnia 6
agitation 6
hypoproteinemia 6
emaciation 6
epigastric pain 6
memory loss 5
sleepiness 5
acidity 5
HSA 5
bone pain 5
ataxia 5
ENT 4
dyspnea 4
hyperoxia 3
vertigo 3
regurgitation 3
acute pain 3
microbial colonization 3
autodigestion 3
thinning 3
stomach distension 3
blurred vision 3
splenomegaly 3
syncope 3
cyanosis 3
tonic-clonic seizure 3
asthenia 3
myalgia 2
wheezing 2
generalized rash 2
heartburn 2
tingling 2
enuresis 2
rhinorrhea 2
cough 2
paresis 2
paresthesia 2
more...
Drug
Glucagon 3742
Liraglutide 243
Exenatide 157
lysine 139
Secretin 117
Gel 103
Cardiovasc 92
Nephron 89
Growth hormone 88
Growth hormone 87
Portal 80
PTH 67
caffeine 54
NADH 53
Asn 52
Alanine 51
Forskolin 43
GRF 40
lactose 39
Phentolamine 34
Fructose 34
Atropine 33
Dermatol 31
Theophylline 31
Ethanol 31
Pramlintide 29
CTX 29
CPR 29
Angiotensin II 28
CTX 26
Teduglutide 26
CTX 26
Glycerol 24
ROS 22
Sandostatin 22
Sandostatin 22
Bifidobacterium 21
nitroglycerin 19
Albumin 18
ascorbate 17
IL-2 16
Activin 15
ENT 15
ICI 15
CaCl2 15
ADM 15
Histamine 14
MAP 14
Clonidine 14
CaCl2 14
GHRP 14
CSF 14
NH3 14
vitamin E 14
CaCl2 14
citric acid 13
Nephron 13
Aprotinin 13
Scopolamine 12
Monit 12
Ouabain 12
Diurnal 11
HCG 11
Humulin 11
Buscopan 11
Glutathione 10
IFN-gamma 10
DMI 10
DNase I 9
Rosiglitazone 9
NVP 9
Dial 9
Januvia 9
TAT 9
ROC 8
Galactose 8
Leaf 8
EPI 8
Indomethacin 8
Amiloride 7
more...
Enzyme
adenylate cyclase 854
protein kinase 702
phosphorylase 325
phosphoenolpyruvate carboxykinase 259
dipeptidyl peptidase IV 245
phosphodiesterase 240
phosphoenolpyruvate carboxykinase 239
phosphoenolpyruvate carboxykinase 236
mitogen-activated protein kinase 205
glucokinase 205
protein kinase C 193
AMPK 174
AMP-activated protein kinase 172
pyruvate kinase 165
collagenase 158
trypsin 139
renin 133
peroxidase 132
glucose-6-phosphatase 131
ATPase 105
lipase 103
ERK 98
caspase-3 86
alpha-glucosidase 82
tyrosine aminotransferase 79
phospholipase C 79
alkaline phosphatase 76
AMPK 75
tyrosine hydroxylase 70
catalase 68
alanine aminotransferase 63
pyruvate carboxylase 62
superoxide dismutase 61
lipoprotein lipase 60
phosphofructokinase 58
acetyl-CoA carboxylase 57
calcineurin 56
phosphorylase kinase 55
luciferase 53
lactate dehydrogenase 52
CPT 52
phosphatidylinositol 3-kinase 52
glucose-6-phosphate dehydrogenase 46
focal adhesion kinase 45
CD10 43
MEK 42
ornithine decarboxylase 41
aspartate aminotransferase 40
hexokinase 38
furin 37
chymotrypsin 37
CPR 36
glutathione peroxidase 34
reverse transcriptase 34
adenosine deaminase 33
adenosine deaminase 33
pyruvate dehydrogenase 32
sucrase 30
NO synthase 30
alcohol dehydrogenase 30
insulin-degrading enzyme 30
GSK 28
invertase 28
creatine kinase 27
hormone-sensitive lipase 27
fructose 1,6-bisphosphatase 27
ACS 26
pyruvate dehydrogenase 26
guanylate cyclase 26
pyruvate dehydrogenase 26
CPT 25
6-phosphofructo-2-kinase 25
elastase 25
RNase 24
chloramphenicol acetyltransferase 24
RNase 24
phosphoinositide 3-kinase 24
CPT 22
ACE 22
phospholipase A2 22
more...
Compound
glucose 12790
Glucagon 3742
Clin 2009
Dec 1851
Insulin 1835
cAMP 1591
arginine 1308
calcium 1249
AMP 1090
sodium 861
alanine 710
water 628
Pac 605
DPP 586
ATP 570
DNA 543
glycerol 533
oxygen 502
Diabetol 407
leucine 402
phosphate 382
urea 373
galactose 356
tyrosine 348
ACTH 318
noradrenaline 317
acetate 306
His 295
nitrogen 273
lysine 265
potassium 251
serine 225
glutamine 217
methionine 215
Phe 209
Adrenal 208
GTP 194
glutamate 193
ethanol 188
alloxan 181
Diabetol 178
Ile 178
threonine 161
NH2 161
sulfate 152
zinc 142
FFA 141
nitric oxide 140
tryptophan 138
ADP 137
tryptophan 135
isoleucine 135
cGMP 134
ADP 134
ADP 134
isoleucine 133
tryptophan 132
tryptophan 132
salt 126
creatinine 121
STZ 120
Secretin 117
5-HT 115
aldosterone 112
Gly 110
nicotinamide 109
Mg2+ 108
prostaglandin E1 105
Asp 105
valine 105
CO2 101
TSH 100
proline 97
ammonia 95
TNF 93
NAD 87
Cortisol 86
Metformin 86
Metformin 85
Cardiol 84
more...