Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P01189 (
beta-endorphin
)
21,003
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
beta-endorphin
21003
ACTH
4023
adrenocorticotropic hormone
2752
Sep
1380
prolactin
1202
insulin
988
growth hormone
934
vasopressin
889
corticotropin-releasing factor
871
proopiomelanocortin
816
dynorphin
770
MSH
766
Mol
710
neuropeptide Y
669
somatostatin
644
substance P
544
CRH
526
opioid receptor
521
leptin
515
arginine vasopressin
501
oxytocin
496
Gen
397
cytokine
351
Met-enkephalin
341
AMP
331
glucagon
306
glucocorticoid receptor
303
adenylate cyclase
290
angiotensin II
285
polypeptide
281
renin
278
CRF
272
calcitonin
268
cholecystokinin
264
Met
259
neurotensin
258
CD105
256
LHRH
254
agouti
245
thyrotropin-releasing hormone
221
lipopolysaccharide
212
ART
208
GABA
200
tyrosine hydroxylase
199
follicle-stimulating hormone
189
melanocortin receptor
179
MC3
179
tyrosinase
177
Leu-enkephalin
171
HPA
169
ghrelin
168
tumor necrosis factor
164
urocortin
155
bombesin
153
IL-6
153
proenkephalin
151
FSH
150
PRL
150
Leu5
150
ACTH receptor
147
melanin-concentrating hormone
146
IL-1
144
gut
141
gastrin
140
c-fos
140
LPH
139
ATP
137
TRH
136
hormone receptor
130
thymus
129
peroxidase
129
vasoactive intestinal peptide
128
orexin
128
5-hydroxytryptamine
127
galanin
127
CSF
116
olfactory
115
glycoprotein
115
X-linked
112
leptin receptor
111
more...
Disease
tumor
836
depression
752
obesity
611
Cushing's syndrome
567
Cushing's disease
485
hypertension
356
cancer
330
melanoma
317
adenoma
307
diabetes
305
chronic renal failure
303
hypercortisolism
282
hypoglycemia
268
Pituitary
263
adrenal insufficiency
259
major depressive disorder
211
cold
195
pituitary adenoma
175
HPA
169
pituitary tumor
166
carcinoma
151
SEM
120
hyperphagia
116
carcinoid
110
psychological stress
108
epilepsy
100
hyperglycemia
98
alcoholism
95
metastases
95
Alzheimer's disease
92
Nelson
86
West
84
pertussis
84
Addison's disease
82
cholera
82
ACTH deficiency
82
congenital adrenal hyperplasia
80
ischemia
79
schizophrenia
78
hypopituitarism
77
Addison's disease
77
multiple sclerosis
76
arthritis
74
anxiety disorders
74
aggression
74
posttraumatic stress disorder
72
chronic pain
72
addiction
69
anorexia nervosa
69
stroke
69
sepsis
68
hypercortisolemia
65
adrenal hyperplasia
65
rheumatoid arthritis
64
sepsis
64
neuroblastoma
63
aldosteronism
63
pheochromocytoma
61
SDS
60
type 2 diabetes
59
hyperinsulinemia
57
hyperprolactinemia
57
acromegaly
57
adrenal adenoma
53
hypothyroidism
53
polycystic ovary syndrome
52
amenorrhea
52
uterus
50
social stress
48
asthma
48
essential hypertension
48
psychosis
47
Anterior
47
lung carcinoma
46
diabetes insipidus
46
Parkinson's disease
45
Evans
45
dehydration
45
osteoporosis
44
hyperandrogenism
44
more...
Symptom
pain
740
analgesia
444
anesthesia
242
acute stress
201
seizures
194
anorexia
147
fatigue
100
headache
89
hypothermia
77
starvation
53
weakness
47
exhaustion
46
vomiting
42
hunger
40
nausea
39
overweight
39
Cushingoid
38
Cushingoid
38
insomnia
30
cachexia
28
tremor
28
diarrhea
25
polyuria
25
angina
25
functional recovery
24
lethargy
24
Ill
22
polydipsia
21
masculinization
19
abdominal pain
19
flushing
19
hypercapnia
18
myoclonus
18
agitation
18
collapse
17
discomfort
17
acute pain
16
discomfort
15
sleepiness
15
nausea and vomiting
15
spasm
14
low back pain
14
dyspnea
12
dizziness
11
cancer pain
11
ataxia
11
despair
10
chest pain
9
syncope
9
myalgia
9
respiratory distress
8
dystonia
8
catatonia
8
back pain
8
hot flushes
7
Postoperative pain
7
vertigo
6
leg edema
6
bradykinesia
6
constipation
6
thinning
6
bone pain
5
emaciation
5
Depressive symptoms
5
hypotonia
5
anosmia
5
hypersomnia
5
cough
5
hepatomegaly
4
Spots
4
memory loss
4
hoarseness
4
POA
4
paresis
4
acidity
4
colic
4
decreased appetite
4
limb pain
4
chorea
4
apathy
4
more...
Drug
Dermatol
174
lysine
139
CSF
125
Gel
103
Nephron
69
ICI
60
MAP
58
IL-2
56
Asn
44
Angiotensin II
43
Growth hormone
41
DEX
41
Growth hormone
41
Ethanol
39
Forskolin
38
IFN-gamma
33
EE2
32
Portal
29
hCRH
29
Cardiovasc
29
Clonidine
25
caffeine
25
Glucagon
23
Histamine
16
Cortrosyn
15
GRF
15
nitroglycerin
15
Indomethacin
15
ascorbate
14
GHRP
14
Ketoconazole
13
Cortrosyn
13
vitamin E
12
Diurnal
12
CTX
12
L-tyrosine
11
Luteinizing
11
Nephron
10
Retinoic acid
10
Fraction
10
CDP
9
Captopril
9
Ringer's solution
9
Estrogens
9
PCP
9
CaCl2
9
CaCl2
9
CaCl2
9
ABC
9
Leaf
9
PCB
8
Prednisone
8
Pitressin
8
Atropine
8
ENT
8
Ouabain
8
Apomorphine
8
IFN-beta
8
PTH
8
G418
7
DDAVP
7
Domperidone
7
DDAVP
7
CoCl2
7
Monit
7
HCH
7
CoCl2
7
Biopolymers
7
9-THC
7
Asthma
7
ROS
6
CAM
6
Acthar
6
Sulpiride
6
NADH
6
Dial
6
DMI
6
Trilostane
5
TAT
5
Fragment
5
more...
Enzyme
adenylate cyclase
298
protein kinase
291
renin
278
tyrosine hydroxylase
195
tyrosinase
176
peroxidase
160
protein kinase C
152
mitogen-activated protein kinase
102
trypsin
102
phosphodiesterase
90
ERK
88
CD10
73
alkaline phosphatase
66
AMPK
64
ATPase
58
reverse transcriptase
53
acetylcholinesterase
48
phospholipase C
48
furin
44
luciferase
43
NO synthase
42
21-hydroxylase
41
collagenase
36
RNase
34
RNase
34
lipase
33
acid phosphatase
31
HSD
31
carboxypeptidase E
27
AMP-activated protein kinase
26
superoxide dismutase
26
cytochrome P-450scc
25
nucleotide pyrophosphatase
25
DCF
24
calcineurin
24
focal adhesion kinase
23
MAP
22
ACE
22
phospholipase A2
22
dopamine beta-hydroxylase
22
carboxypeptidase B
20
NOS
20
lactate dehydrogenase
19
11beta-hydroxysteroid dehydrogenase
19
choline acetyltransferase
19
ornithine decarboxylase
18
RNA polymerase
18
creatine kinase
18
guanylate cyclase
18
catalase
18
MEK
18
enolase
18
chymotrypsin
17
lipoxygenase
17
adenosine deaminase
16
adenosine deaminase
16
subtilisin
15
phenylethanolamine N-methyltransferase
15
monoamine oxidase
15
proprotein convertase
14
pepsin
14
glutamate decarboxylase
14
3beta-hydroxysteroid dehydrogenase
13
caspase-3
13
S1 nuclease
13
PDE
12
chloramphenicol acetyltransferase
12
cholinesterase
12
alcohol dehydrogenase
12
cholesterol esterase
12
ribonuclease
11
ribonuclease
11
PRA
11
p-nitrophenylphosphatase
11
hormone-sensitive lipase
11
phosphoenolpyruvate carboxykinase
11
HPI
10
phosphoenolpyruvate carboxykinase
10
lysozyme
10
phosphoenolpyruvate carboxykinase
10
more...
Compound
ACTH
4427
alpha-MSH
1469
Dec
1446
Clin
1071
glucose
696
cAMP
680
NPP
660
water
603
methionine
578
calcium
573
aldosterone
511
sodium
505
arginine
426
Corticotropin
422
Phe
413
tyrosine
404
DNA
399
leucine
375
AMP
354
noradrenaline
342
lysine
333
Naloxone
318
ethanol
317
5-HT
307
NH2
304
sulfate
301
Gly
292
Cortisol
291
potassium
247
Adrenal
223
TSH
217
glutamate
214
His
212
GABA
209
GABA
203
acetate
193
phosphate
184
oxygen
180
nitric oxide
177
TRH
171
Morphine
156
Dexamethasone
140
ATP
137
alanine
134
gamma-aminobutyric acid
128
salt
123
threonine
118
Corticosterone
91
Asp
87
tryptophan
83
Insulin
82
Substance P
81
DAMGO
80
tryptophan
79
tryptophan
79
tryptophan
79
GTP
79
Dopamine
77
TNF
73
acetic acid
73
Vasopressin
73
CO2
72
SDS
68
serine
66
HCl
64
ICI
60
Dynorphin
60
Norepinephrine
59
zinc
58
cGMP
58
hydroxyindoleacetic acid
58
Ile
57
silver
56
Angiotensin II
55
PGE2
54
iron
54
DHA
53
D-Ala
51
DSM
51
galactose
50
more...