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Query: UNIPROT:P01189 (beta-endorphin)
 21,003 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Basal alkaline secretion of the denervated rat ileum was monitored by a pH-stat method. Changes of transepithelial electrical potential difference (PD) were also continuously registered. In other experiments net fluid transport was measured with a gravimetric method. The importance of the enteric nervous system for the recorded variables was investigated by giving i.v. hexamethonium, neuropeptide Y (NPY) or methionine-enkephalin or by stimulating electrically the mesenteric nerves surrounding the superior mesenteric artery. Alkaline secretion was inhibited by about 20% by mesenteric nerve stimulation or by neuropeptide Y (NPY) or met-enkephalin i.v. A somewhat greater inhibition (approximately 30%) of transepithelial electrical potential difference was elicited by the mesenteric nerve stimulation and NPY whereas met-enkephalin did not cause any transepithelial electrical potential difference change. Net fluid absorption was markedly diminished (by approximately 65-75%) by met-enkephalin but not by NPY. The cellular mechanisms underlying alkaline secretion were investigated by means of amiloride, SITS and acetazolamide. The basal alkaline secretion and transepithelial electrical potential difference were not influenced by 10(-3)M or 10(-4) SITS. In contrast 10(-3) M amiloride caused a significant increase of alkaline secretion but not of transepithelial electrical potential difference. A 35% reduction in the alkaline secretion but not transepithelial electrical potential difference was observed after acetazolamide had been given intravenously. A similar decrease was observed after giving hexamethonium. We conclude: (1) Enteric nerves are of comparatively small importance in controlling the ileal alkaline secretion recorded during basal conditions; (2) About 35% of the basal ileal alkaline secretion is carbonic anhydrase dependent. This mechanism is not influenced by nicotinic receptor blockade; (3) Under the present experimental conditions there may be an alkaline secretion which is concealed by a simultaneously operating Na+/H+ exchanger and; (4) No consistent quantitative correlation exists between alkaline secretion, transepithelial electrical potential difference and net field transport in the denervated rat ileum.
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PMID:On the mechanisms of the basal alkaline secretion in the rat ileum in vivo. 167 11

Aquatic breeding-condition newts kept at 5, 11, or 18 degrees showed temperature-dependent changes in body weight (BW), tail height, plasma [Na+], hematocrit, integumental osmotic permeability, urine production, and transepithelial potential. Net urine production could account for the change in weight observed in animals kept at 11 and 18 degrees, suggesting that initial weight change results from a reduction in extracellular volume. Weight loss was correlated with increased hematocrit and plasma [Na+]. In another experiment, newts were sham-hypophysectomized (sham-HX) or hypophysectomized (HX) and injected with saline, ovine prolactin (PRL), ovine growth hormone (GH), or porcine adrenocorticotropic hormone (ACTH) and maintained at 5 degrees for 13 days. All animals lost 3-7% of their initial BW. Plasma [Na+] was reduced in animals injected with hormone compared with both sham-operated and saline-injected controls. Following an increase in water temperature to 11 degrees for 13 days, weight loss in sham-operated and ACTH-injected newts increased to 16% of BW compared with a total of 4-8% in newts injected with PRL, GH, or saline. In this experiment also, loss of body weight was correlated with increased plasma [Na+]. Although measurements of plasma Na+ concentrations indicated that ACTH caused "sodium retention," estimates of changes in total extracellular Na+ revealed that both sham-operated and ACTH-injected newts experienced a net sodium loss. In Taricha granulosa, warm temperatures and ACTH (presumably acting via interrenal hormones) appear necessary for the fluid and electrolyte loss which accompanies the transition from the aquatic to the terrestrial condition.
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PMID:Osmoregulatory changes during the aquatic-to-terrestrial transition in the rough-skinned newt, Taricha granulosa: the roles of temperature and ACTH. 609 8

Long-term intake of ethanol decreases food intake and inhibits growth in experimental rats. The aim of this study was to determine the effect of 4-week oral ethanol ingestion on plasma leptin and adrenal function. Male 45-day-old Wistar rats were divided into three groups: absolute control (AC), ethanol (E) administered 10% (wt/vol) ethanol instead of tap water, and pair-fed (PF) given an amount of food corresponding to the food intake of E animals. E rats consumed less pelleted diet (74% cumulative total intake); however, this caloric deficit was compensated by ethanol ingestion. Net water intake in E animals was 76% of that in the control groups. The body growth of both E and PF rats was stunted compared with AC animals, but E rats were heavier than PF rats. The plasma leptin level was similar in E and AC and decreased in PF animals. There were no differences in plasma osmolality or glycemia among the three groups. Plasma insulin was decreased in PF compared with both AC and E rats. Plasma corticosterone was not affected by ethanol, but was increased in the food-restricted (PF) group. Although there were no differences in basal adrenal corticosterone production in vitro, there was a slightly higher response to corticotropin (ACTH) in E rats. We conclude that drinking 10% ethanol decreased the dietary intake and body growth. These changes were not mediated by plasma leptin changes. Although alcohol ingestion and its energy content theoretically normalized the total energy intake and prevented the decrease of plasma leptin, the growth of young rats was inhibited. Drinking 10% ethanol instead of tap water for 4 weeks did not stimulate basal adrenal activity.
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PMID:Four-week ethanol intake decreases food intake and body weight but does not affect plasma leptin, corticosterone, and insulin levels in pubertal rats. 978 33

Tree carbon (C) uptake (net primary productivity excluding fine root turnover, NPP') in a New Zealand Pinus radiata D. Don plantation (42 degrees 52' S, 172 degrees 45' E) growing in a region subject to summer soil water deficit was investigated jointly with canopy assimilation (A(c)) and ecosystem-atmosphere C exchange rate (net ecosystem productivity, NEP). Net primary productivity was derived from biweekly stem diameter growth measurements using allometric relations, established after selective tree harvesting, and a litterfall model. Estimates of A(c) and NEP were used to drive a biochemically based and environmentally constrained model validated by seasonal eddy covariance measurements. Over three years with variable rainfall, NPP' varied between 8.8 and 10.6 Mg C ha(-1) year(-1), whereas A(c) and NEP were 16.9 to 18.4 Mg C ha(-1) year(-1) and 5.0-7.2 Mg C ha(-1) year(-1), respectively. At the end of the growing season, C was mostly allocated to wood, with nearly half (47%) to stems and 27% to coarse roots. On an annual basis, the ratio of NEP to stand stem volume growth rate was 0.24 +/- 0.02 Mg C m(-3). The conservative nature of this ratio suggests that annual NEP can be estimated from forest yield tables. On a biweekly basis, NPP' repeatedly lagged A(c), suggesting the occurrence of intermediate C storage. Seasonal NPP'/A(c) thus varied between nearly zero and one. On an annual basis, however, NPP'/A(c) was 0.54 +/- 0.03, indicating a conservative allocation of C to autotrophic respiration. In the water-limited environment, variation in C sequestration rate was largely accounted for by a parameter integrative for changes in soil water content. The combination of mensurational data with canopy and ecosystem C fluxes yielded an estimate of heterotrophic respiration (NPP' - NEP) approximately 30% of NPP' and approximately 50% of NEP. The estimation of fine-root turnover rate is discussed.
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PMID:Net ecosystem productivity, net primary productivity and ecosystem carbon sequestration in a Pinus radiata plantation subject to soil water deficit. 1265 99

In many East Asia regions, spring (from March to May) precipitation is an important restricting factor to vegetation growth, and atmospheric circulation system may influence spring precipitation patter. It is helpful to under the response of ecosystem to climate change by studying the influence of atmospheric circulation system on the coupling relationship between spring net primary productivity and precipitation. Driving CASA (Carnegie-Ames-Stanford Approach) NPP (Net Primary Productivity) model, we estimated spring NPP for East Asia area (70 degrees E-1 70 degrees E, 10 degrees N-70 degrees N) from 1982 to 1999, and by the method of singular value decomposition we further analyzed the coupling features of spring NPP with precipitation. The result showed that the response features of NPP to precipitation were mainly embodied within the leading six NPP-precipitation paired-modes. The interpretation rates of the leading six paired-modes to the covariance of NPP-precipitation were 42.91, 23.29, 9.96, 5.60, 5.04 and 3.95%, respectively, and total to 90.75%. The temporal correlation coefficients of the leading six paired-modes were 0.830, 0.889, 0.841, 0.747, 0.912 and 0.923, respectively, and all the correlations were significant at significant level of 0.001. In some high latitude regions, there was no obviously corresponding relationship between NPP and precipitation in the leading two paired-modes, and the reason of it may be that spring temperature was the main restricting factor to NPP. In middle and low latitude regions, the effect of precipitation on NPP was relatively more notable. Nine atmospheric circulation factors in spring affected the patterns of NPP and precipitation greatly, and the regions with interpretation rate over 50% shared 60.41 and 65.58% of the whole study area, respectively.
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PMID:The role of atmospheric circulation system playing in coupling relationship between spring NPP and precipitation in East Asia area. 1804 7

In addition to their aesthetic and environmental qualities, reconstructed prairies can act as C sinks and potentially offset rising atmospheric CO(2) concentration. The objective of this study was to quantify C budget components of newly established prairies on previously cultivated land. Net ecosystem production (NEP) was estimated using a C budgeting approach that assessed SOC content, soil surface CO(2)-C emission, and above- and belowground plant biomass. Study was conducted in southern Iowa, in 2005 to 2007. Results show that differences between sites for potential total C input were primarily due to root biomass contributions, which ranged from 0.8 to 5.4 Mg C ha(-1). Average potential aboveground biomass C input was 2.7 Mg C ha(-1) in 2006 and 5.5 Mg C ha(-1) in 2007. Total soil CO(2)-C emissions from heterotrophic respiration increased as prairie age increased from 2.9 to 4.0 Mg C ha(-1) and 3.1 to 4.7 Mg C ha(-1) in 2006 and 2007, respectively. Determination of NEP showed that the 1998 and 2003 reconstructed prairie sites had the greatest potential for soil C sequestration at 4.1 and 4.4 Mg C ha(-1). Increases in SOC content were only observed in the youngest established prairie site (2003) and the no-till site in 2003 at 2.1 and 2.6 Mg C ha(-1) yr(-1), respectively. Declines of SOC sequestration rates occurred when potential C equilibrium was reached (R(h) = NPP) within 10 yr since prairie establishment.
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PMID:Soil carbon dynamics and carbon budget of newly reconstructed tall-grass prairies in south central Iowa. 2004 1

Detailed understanding of a possible decoupling between climatic drivers of plant productivity and the response of ecosystems vegetation is required. We compared trends in six NDVI metrics (1982-2010) derived from the GIMMS3g dataset with modelled biomass productivity and assessed uncertainty in trend estimates. Annual total biomass weight (TBW) was calculated with the LINPAC model. Trends were determined using a simple linear regression, a Thiel-Sen medium slope and a piecewise regression (PWR) with two segments. Values of NDVI metrics were related to Net Primary Production (MODIS-NPP) and TBW per biome and land-use type. The simple linear and Thiel-Sen trends did not differ much whereas PWR increased the fraction of explained variation, depending on the NDVI metric considered. A positive trend in TBW indicating more favorable climatic conditions was found for 24% of pixels on land, and for 5% a negative trend. A decoupled trend, indicating positive TBW trends and monotonic negative or segmented and negative NDVI trends, was observed for 17-36% of all productive areas depending on the NDVI metric used. For only 1-2% of all pixels in productive areas, a diverging and greening trend was found despite a strong negative trend in TBW. The choice of NDVI metric used strongly affected outcomes on regional scales and differences in the fraction of explained variation in MODIS-NPP between biomes were large, and a combination of NDVI metrics is recommended for global studies. We have found an increasing difference between trends in climatic drivers and observed NDVI for large parts of the globe. Our findings suggest that future scenarios must consider impacts of constraints on plant growth such as extremes in weather and nutrient availability to predict changes in NPP and CO2 sequestration capacity.
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PMID:Trends in Global Vegetation Activity and Climatic Drivers Indicate a Decoupled Response to Climate Change. 2646 47

Over the past 100 years, human activity has greatly changed the rate of atmospheric N (nitrogen) deposition in terrestrial ecosystems, resulting in N saturation in some regions of the world. The contribution of N saturation to the global carbon budget remains uncertain due to the complicated nature of C-N (carbon-nitrogen) interactions and diverse geography. Although N deposition is included in most terrestrial ecosystem models, the effect of N saturation is frequently overlooked. In this study, the IBIS (Integrated BIosphere Simulator) was used to simulate the global-scale effects of N saturation during the period 1961-2009. The results of this model indicate that N saturation reduced global NPP (Net Primary Productivity) and NEP (Net Ecosystem Productivity) by 0.26 and 0.03 Pg C yr-1, respectively. The negative effects of N saturation on carbon sequestration occurred primarily in temperate forests and grasslands. In response to elevated CO2 levels, global N turnover slowed due to increased biomass growth, resulting in a decline in soil mineral N. These changes in N cycling reduced the impact of N saturation on the global carbon budget. However, elevated N deposition in certain regions may further alter N saturation and C-N coupling.
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PMID:Simulated effects of nitrogen saturation on the global carbon budget using the IBIS model. 2796 43

Climate change and human activities are two key factors that affect grassland ecosystem. Accurately estimating the effects of these two factors on grassland dynamics and understanding the driving forces of the dynamics are important in controlling grassland degradation. In this study, the potential Net Primary productivity (NPPP) and the difference between NPPP and actual NPP (NPPA) are used as indicators of climate change and human activities on grassland ecosystem in Xinjiang. An overall grassland NPPA increase than decrease (69.7% vs 30.3%) is found over the study period of 2000 to 2014. While human activities played a dominant role for such a NPPA increase, both human activities and climate change contributed almost equally to the grassland NPPA decrease. Within the three types of grasslands in Xinjiang, the desert grassland showed the greatest NPPA increasing trend that mostly attributed to human activities; the meadow showed an overall NPPA decreasing trend that was mainly caused by human activities; the steppe showed similar NPPA decreasing and increasing trend in terms of area percentage. Based on this study, our recommendations are (1) to continue the grazing prohibition policy in desert grassland and (2) to extensively implement the rest grazing policy in steppe and meadow grasslands.
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PMID:Grassland dynamics in response to climate change and human activities in Xinjiang from 2000 to 2014. 3097 17

Analysing the link between terrestrial ecosystem productivity (i.e., Net Primary Productivity: NPP) and extreme climate conditions is vital in the context of increasing threats due to climate change. To reveal the impact of changing extreme conditions on NPP, a copula-based probabilistic model was developed, and the study was carried out over 25 river basins and 10 vegetation types of India. Further, the resiliency of the terrestrial ecosystems to sustain the extreme disturbances was evaluated at annual scale, monsoon, and non-monsoon seasons. The results showed, 15 out of 25 river basins were at high risks, and terrestrial ecosystems in only 5 river basins were resilient to extreme climatic conditions. Moreover, at least 50% area under 4 out of 10 vegetation cover types was found to be facing high chances of a drastic reduction in NPP, and 8 out of 10 vegetation cover types were non-resilient with the changing extreme climate conditions.
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PMID:Assessment of Risk and Resilience of Terrestrial Ecosystem Productivity under the Influence of Extreme Climatic Conditions over India. 3183 70


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