Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P01189 (beta-endorphin)
21,003 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Aerobic exercise which resulted in a significant improvement in cardiovascular functioning had no more effect on psychological mood states than did the placebo control of participation in nonaerobic recreational games or no exercise and sport at all (N = 430 college students). Beta-endorphin levels with the 41 depressed subjects were not a biochemical link that might explain the possible influence of physical activity on depression.
Percept Mot Skills 1986 Dec
PMID:Effect of levels of exercise on psychological mood states, physical fitness, and plasma beta-endorphin. 294 97

The effects of met-enkephalin on the acquisition and retention over 10 days of a perceptual motor skill were investigated. Mice were randomly assigned to either one of two experimental groups (1-mg or 3-mg injections per 1-kg of body weight of met-enkephalin) or one of two control groups (dH2O injections). During the acquisition phase of the study, they were separated into "slow" and "fast" learners on the basis of their skill in negotiating a water maze. The results indicated an inhibitory effect of met-enkephalin in the 3-mg condition in the retention phase of the experiment. Subjects' skill was not implicated as a critical factor in retention of this simple task.
Percept Mot Skills 1988 Jun
PMID:Subjects' skill and biphasic effects of met-enkephalin upon the acquisition and retention of a perceptual motor task. 340 16

Considerable research has shown significant increases in beta-endorphin levels after aerobic activity. These increases and their accompanying euphoric effect have been suggested as a possible psychophysiological mechanism underlying the exercise-dependence syndrome. The relationship between plasma beta-endorphin levels and a tendency towards exercise dependence, however, has not been established. To examine this relationship, 8 women trained in aerobic dance completed an exercise-dependence assessment prior to participation in a 45-min. session of continuous aerobic dance. Plasma beta-endorphin concentration was measured both prior to and following the aerobics routine. A Student t test for paired observations indicated that mean plasma beta-endorphin levels (+/- SE) were significantly higher after the aerobics routine (11.96 +/- 1.3 pg beta-EP.ml-1) than preexercise levels (8.62 +/- 1.4). However, beta-endorphin difference values (% change) were not significantly correlated with scores on the exercise-dependence survey. Those data suggest that scores on exercise dependence are not related to changes in plasma beta-endorphin levels after aerobic exercise.
Percept Mot Skills 1993 Dec
PMID:Beta-endorphin response to endurance exercise: relationship to exercise dependence. 828 51

Research examining the relationship between beta-endorphin immunoreactivity and affect has resulted in equivocal findings. To examine this relationship further, 10 male and 10 female college-age students participated in a controlled free-weight exercise session. Blood plasma samples were procured both prior to and following the exercise bout and beta-endorphin levels were determined by immunoassay. Analysis indicated that plasma beta-endorphin levels following exercise were significantly decreased from pre-exercise levels. Pearson correlations showed no significant relationship between pre- or postexercise plasma beta-endorphins and either total mood disturbance or Profile of Mood States subscores. The data support previous failure of resistance exercise to produce an increase in beta-endorphin immunoreactivity as well as the lack of a significant relationship between affect and the beta-endorphin response to exercise.
Percept Mot Skills 1993 Apr
PMID:Beta-endorphins and mood states during resistance exercise. 848 42