Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P01189 (
beta-endorphin
)
21,003
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The endogenous central nervous tissue substance called
MLC
(morphine-like compound) is shown to bind to the opiate receptors of the mouse neuroblastoma X glioma hybrid cell line NG108-15. The interaction of
MLC
with these opiate receptors is noncooperative, as is the interaction of morphine, naloxone, and Leu-enkephalin with these receptors. A specific antibody to morphine will bind
MLC
but will not bind
beta-endorphin
, Leu-enkephalin, or Met-enkephalin. It would appear, therefore, that
MLC
can be considered to be a different type of endogenous ligand for the opiate receptor.
...
PMID:Binding of the endogenous nonpeptide morphine-like compound to opiate receptors. 20 Sep 39
