Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P01185 (
vasopressin
)
23,126
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Contemporaneous movements of Rb86 cations and of P(32) orthophosphate across isolated rabbit mesentery display kinetic patterns that are generally associated with passive diffusion. Vasopressin at a concentration of 100 milliunit/ml produced a significant increase in the permeability constant for P(32) and at the same time a significant decrease in the permeability to Rb(86). At lower hormone concentrations (0.1 milliunit/ml) the P32 response was less marked but still significant (P < .01), while the Rb(86) effect was not (P > .05).
Hyaluronidase
did not mimic these actions of
vasopressin
.
...
PMID:Action of vasopressin on the permeability of mesentery. 1386 15
Effect of
vasopressin
on the expression of
Hyal-1
and Hyal-2 genes in different functional zones of Wistar and homozygous
vasopressin
-defficient Brattlboro rat kidneys was analysed using RT-PCR mehod. It was found that, in Wistar rats the content of
Hyal-1
mRNA was higher in the medulla than in other kidney zones at the normal water and food regimen. The level of
Hyal-1
mRNA in the cortex and the medulla of Brattlboro rat kidney exceeded that of papilla. There were no significant differences in the Hyal-2 mRNA content detected between functional zones of Wistar and Brattlboro rat kidneys. The treatment by dDAVP, the agonist of V2
vasopressin
receptor (Desmopressin, 10 microg/100 g b.w.i.p. twice a day for two days) induced an increase in urine osmolality and significant increase in the
Hyal-1
and Hyal-2 mRNA content in the medulla without changes in the cortex and papilla. The effect was more pronounced in Brattlboro rat kidney. These results demonstrate that, in control conditions, genes encoding
Hyal-1
and Hyal-2 were expressed independently in all functional kidney zones in the both in normal Wistar and in
vasopressin
-defficient Brattlboro rats. Desmopressin (dDAVP) exerts a stimulating effect on
Hyal-1
and Hyal-2 gene expression in the medulla.
...
PMID:[Effect of dDAVP, agonist of V2 vasopressin receptor on the hyaluronidase-1 and hyaluronidase-2 gene expression in the kidneys of Wistar and Brattleboro rats]. 1765 Jun 18
