Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P01185 (
vasopressin
)
23,126
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The aim of our study was to analyze
vasopressin
secretion rate from hypothalamic neurons in Krushinsky-Molodkina (KM) rats prone to audiogenic epilepsy in control and during audiogenic seizures. We evaluated
vasopressin
content in blood serum and
neurophysin II
amount in the neurohypophysis in KM rats as well as in Wistar rats. Obtained data demonstrated decreasing of
vasopressin
in the blood and at the same time increasing of
neurophysin II
content in the neurohy- pophysis of KM rats that revealed an inhibition of
vasopressin
release into blood circuit. The analysis of
vasopressin
content in blood on the different stages of
audiogenic seizure
showed significant increasing of
vasopressin
at clonustonus. Thus, we obtained first demonstration that in KM rats prone to audiogenic seizures
vasopressin
secretion rate is decreased in comparison to Wistar rats. Significantly upregulated
vasopressin
in blood at cloniconic stages reveals a participation of vasopressinergic neurosecretory system in the expression of audiogenic seizures.
...
PMID:[THE INVESTIGATION OF VASOPRESSIN SECRETION IN NORMAL CONDITION AND DURING SEIZURE ONSET IN KRUSHINSKY-MOLODKINA RATS]. 2701 28
