Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P01185 (vasopressin)
 23,126 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The syndrome of inappropriate secretion of antidiuretic hormone (ADH) or SIADH has been so far reported in various disorders. However, to our knowledge, no case of SIADH associated with adult onset Still's disease (AOSD) has been described in the literature. We report on a patient who developed inappropriate secretion of antidiuretic hormone (SIADH) during the course of adult onset Still's disease (AOSD). The patient developed SIADH associated with pleuritis and improved when pleuritis subsided during the course of steroid therapy. Thus, it seems suggest that SIADH was induced by AOSD which is considered to be related with vasculitis.
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PMID:Inappropriate secretion of antidiuretic hormone (SIADH) in a patient with pleurisy related to adult onset Still's disease. 871 53

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a rare complication of adult Still's disease (ASD). We experienced a male ASD patient who complained of arthralgia and intermittent fever. Chest radiograph and pleural fluid analysis revealed pleurisy with effusion. We diagnosed this patient with SIADH and confirmed the disappearance of hyponatremia and pleurisy after starting treatment with nonsteroidal anti-inflammatory drugs. In this study, we reviewed previous literature and the case of our ASD patient with hyponatremia. This reported case is the fourth case of SIADH in an ASD patient. Further, we found that hyponatremia is a relatively common complication of ASD, and pleurisy has a possibility to develop SIADH in patients with ASD.
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PMID:Syndrome of inappropriate antidiuretic hormone secretion in patients with adult Still's disease. 2131 21