Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P01185 (vasopressin)
 23,126 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The syndrome of inappropriate antidiuretic hormone secretion (SIADH) has not been reported with temporal arteritis. Two cases are presented in which SIADH was related to the occurrence of temporal arteritis. When deterioration of mental status develops in a patient with temporal arteritis, SIADH should be considered in the differential diagnosis.
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PMID:Syndrome of inappropriate antidiuretic hormone secretion in association with temporal arteritis. 716 89

Giant cell arteritis (GCA), a systemic vasculitis of unknown origin, may appear rarely as a paraneoplastic syndrome. Cases secondary to pulmonary neuroendocrine tumors have not been reported. A 75-year-old female developed prednisone-responsive GCA/polymyalgia rheumatica (PMR) shortly followed by syndrome of inappropriate antidiuretic hormone secretion. An 8 mm carcinoid lung tumor with positron emission tomography normal uptake was found. After a thoracoscopic tumor resection the patient experienced complete clinical and laboratory remission. This is the first report of GCA with PMR in the context of carcinoid lung tumor. It emphasizes the role of paraneoplastic vasculitis as a possible cause of GCA.
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PMID:Giant cell arteritis and polymyalgia rheumatica as first manifestation of typical pulmonary carcinoid tumor. 2721 83