Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P01185 (
vasopressin
)
23,126
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We previously found that expression of the
vasopressin
gene is a common feature of human breast cancer. In the present study we first examined 21 different cases of benign
fibrocystic breast disease
for
vasopressin
expression using immunohistochemistry and antibodies directed against
vasopressin
(anti-VP) and against
vasopressin
-associated glycopeptide (anti-VAG). All cases examined were negative for
vasopressin
gene expression using these antibodies. Alternatively, we examined 16 cases of breast ductal carcinoma in situ (DCIS) using the second of these antibodies (anti-VAG), and all of these cases were positive for
vasopressin
gene expression. Our results suggest that products of
vasopressin
gene expression are not markers of cellular proliferation in the breast, and might rather represent an early part of the carcinogenic process in this tissue.
...
PMID:Immunohistochemical evaluation of vasopressin expression in breast fibrocystic disease and ductal carcinoma in situ (DCIS). 1458 71
