Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P01178 (oxytocin)
 15,767 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

To assess the safety of vacuum extraction (V.E.) deliveries under continuous lumbar epidural block (E.B.) with Bupivacain, the modified Krebs score in CTG, Apgar score, cord arterial blood acid-base balance, hypoxanthine, CPK, CPK-BB, Neuron specific enolase and c-AMP were examined. A total of 74 full term oxytocin-induced labors were divided into three groups: A) 21 cases by V.E. under E.B., B) 34 cases under E.B. only, and C) 19 cases without V.E. or E.B. There was no difference in age, gestational weeks in the three groups. However, the incidence of primiparas was highest in group A. Though CTG showed a temporary low Krebs score in group A within 30 minutes after the initiation of E.B., it was found that there was no significant difference between the three groups 30 minutes before parturition. The apgar score, cord arterial blood pH, PO2 and B.E. were also found to be similar in all three groups. Among various kinds of substances in the cord blood, both CPK-BB and c-AMP showed a striking rise in group A, compared to groups B and C. Therefore, the use of V.E. under E.B. might be hazardous to the well-being of the newborn infant.
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PMID:[The assessment of the safety of vacuum extraction deliveries under routine epidural block]. 255 80

Primary dispersed cell cultures were established from fetal diencephalic tissue derived from two stocks of outbred rats. The overall growth pattern, as followed by phase-contrast microscopy and visualized by immunocytochemistry for neurofilament proteins and neuron specific enolase, depended on the age of the donor animal. Stock differences were not revealed by these methods. In contrast, when the cultures were immunostained in order to assess the yield of a specific type of cell, i.e., magnocellular hypothalamic neurons, striking differences were observed between the two stocks of rats. Whereas neurophysin-immunoreactive cells could be grown in cultures established from fetal Chbb: Thom rats at embryonic days 14, 15, and 18, no such cells could be detected in cultures derived from Crl: CD (SD) BR rats older than embryonic day 14. These findings may reflect differences in the differentiation schedule and/or requirements for certain epigenetic and trophic factors between magnocellular neuroblasts derived from the two stocks of rats.
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PMID:Hypothalamo-neurohypophysial neurons in vitro: developmental potentials depend on the donor rat stock. 343 66