Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P01178 (
oxytocin
)
15,767
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A reversed diurnal excretory rhythm of water, creatinine and electrolytes was observed in a woman with fluid retention that first appeared following a head injury 21 years previously. Synthetic
oxytocin
injections were given on the premise that she had a selective deficiency of
oxytocin
with normal vasopressin production. This treatment produced a diuresis and restored a normal excretory rhythm of water, creatinine and electrolytes. Inulin and
PAH
clearance studies showed that
oxytocin
increased the daytime glomerular filtration rate. These results suggest the possibility that
oxytocin
has an additional non-obstetrical physiologic function, viz. the regulation of the normal diurnal rhythm of glomerular filtration rate.
...
PMID:Diuretic effect of oxytocin in a patient with reversed diurnal rhythm of water and electrolyte excretion. 1389 Nov 57
