Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P01178 (oxytocin)
 15,767 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The concentration of lactose in plasma was determined in different sows at all phases of their reproductive cycle and related to the compositional changes in mammary secretion during lactogenesis, established lactation and weaning. Lactose was present in low concentrations (3-4 microM) in the blood of virgin sows and pregnant sows up to 107 days of gestation. From day 4 pre-partum to day 1 pre-partum circulating lactose rose gradually to 34.5 +/- 7.7 microM (mean +/- S.E. of mean). Maximal concentrations of 262 +/- 168.4 microM were reached 6 h after parturition. The concentration of lactose in plasma was correlated with the amount of lactose in mammary secretion (r = 0.88, P less than 0.01) at the beginning of farrowing. During established lactation the concentrations of lactose, Na and K in milk, and of lactose in plasma (72-86 microM), were constant. The concentration of lactose in plasma did not vary significantly during periods of suckling, or after stimulation of milk ejection by oxytocin. However, the amount of lactose in plasma rose significantly (P less than 0.02) after the administration of oxytocin if milk ejection was not accompanied by suckling. The mean plasma concentration of lactose began to rise 36 h after weaning to a peak value of 241.8 +/- 53.6 microM at 48 h; thereafter it declined to 10.2 +/- 2.0 microM by 6 days. This study has shown that lactose concentrations in the plasma vary according to the secretory activity of the mammary gland. Its plasma concentration provides an earlier temporal measure of lactogenesis in individual sows than is obtained either from observation or analysis of mammary secretion.
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PMID:Lactose in plasma during lactogenesis, established lactation and weaning in sows. 670 63

Milk intake (sucking-test weight) by 55 Dorset lambs and milk production (oxytocin-hand milking) by 41 Dorset ewes were measured at 2-wk intervals during the first 8 wk of lactation. Each method indicated that milk yield by ewes was greater at 2 and 4 wk of lactation than at 6 and 8 wk. Daily milk intake by a set of twins (suckling-test weight) was similar to 24-h milk production of their dam (oxytocin-hand milking) when lambs were 2, 4, 6, and 8 wk of age. At 2, 4, and 6 wk postpartum, milk production by ewes nursing single lambs was 200 to 400 g greater than milk intake by lambs due to a larger residual milk. Stage of lactation had a significant effect on protein and fat content of milk but not on lactose. Sex of offspring had no effect on milk yield or protein, fat, and lactose content of milk. Lactose was one percentage unit greater in milk of ewes nursing single lambs; however, the amount of lactose secreted daily was similar for ewes nursing single or twin lambs. Twenty-four-hour milk production by the ewe as determined by the oxytocin-hand milking method was correlated with lamb growth (.67 to .86), with milk intake, as determined by the suckling-test weight method, the next most important variable. Milk composition contributed little toward modeling lamb growth.
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PMID:Milk yield by Dorset ewes as affected by sibling status, sex and age of lamb, and measurement. 672 24