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Query: UNIPROT:P01178 (oxytocin)
 15,767 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The unstressed antepartum cardiotocogram (CTG) is principally judged by two aspects: baseline irregularity, and reaction to Braxton Hicks contractions and fetal movements. A classification into normal, sub-optimal, decelerative, and terminal CTG was devised. The ominous significance of the terminal CTG was confirmed in 26 patients; nine of the fetuses died in utero and the other 17 were delivered by elective Caesarean section; only one newborn was neither small-for-dates nor acidaemic. The significance of the other three categories was evaluated in 428 patients in whom labour was induced. All patients with repeated decelerative antepartum CTG showed signs of fetal distress during labour and most of them required Caesarean section; patients with a normal or sub-optimal CTG rarely showed signs of fetal distress during labour. The incidence of growth retardation was 41 per cent in the combined decelerative and sub-optimal groups against 9 per cent in the normal group. In comparing these results with studies of the oxytocin challenge test, it was concluded that, except in the case of a sub-optimal CTG, the oxytocin challenge test has no place in obstetrics.
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PMID:Diagnostic value of the unstressed antepartum cardiotocogram. 88 22

Qualitative characteristics of uterine contractions in various labors were evaluated by a double guard-ring tocodynamometer, according to the percentages of concurrent and synchronous contractions of two contraction curves when compared with overall contractile activity. For term and preterm labors, percentages of both concurrent and synchronous contractions were significantly higher than those of Braxton Hicks contractions; however, the concurrent and synchronous percentages of preterm labor were lower than those of term labor. Synchronous percentage in groups under maintenance therapy or active treatment in preterm labor were nearly the same; however, the percent concurrent under maintenance therapy was significantly lower than that during active treatment. Both concurrent and synchronous percentages were significantly higher during the active phase of labor than those during the latent phase. The percentages in the latent and active phases of spontaneous contractions were nearly the same; however, they increased significantly during the active phase of augmented contractions, as compared with the latent phase. When the percentages of concurrent and synchronous contractions at each cervical dilatation were retrospectively examined, both values increased significantly between 5 and 6 cm of cervical dilatation. The results suggest that this method can provide important information for understanding the quality of the contraction if attention is paid to the percentages of concurrent and synchronous contractions of two contraction curves and will aid in determining whether oxytocin or tocolysis should be given in term or preterm labor.
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PMID:Qualitative evaluation of uterine contractions recorded by a double guard-ring tocodynamometer. 195 46

The author aimed to compared and simultaneously interpret results from cardiotocographic, ultrasound and hormonal studies and to establish objective criteria, showing the degree of antenatal risk for the fetus. She investigated 176 pregnant women with EPH--gestosis, 136 women with chronologically prolonged pregnancy and 50 healthy pregnant women as a control group. Non stress test (NST, functional oxytocin test, quantitative and semiquantitative evaluation of cardiac frequency of the fetus (CFF) were made. Placental structure was examined by an echograph, as well as the amount of amniotic fluid. Fetal biometry was made as well. Total estrogens (TE) were determined in 24-hour diuresis. It was established that the normal curve of NST was a sign of fetal well-being, but that curve combined with deceleration, together with low values of TE, were criteria for reduced compensatory possibilities of the fetus. NST with decelerations in Braxton Hicks contractions, even part greater than 80% and "terminal" or sharply falling values of TE were signs impending fetal death.
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PMID:[Criteria for the antenatal diagnosis of chronic fetal hypoxia in certain forms of high-risk pregnancy]. 226 73