Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P01178 (
oxytocin
)
15,767
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The effect of
oxytocin
on collagen metabolism in the cervix and lower uterine segment of pregnant women was studied by measuring the incorporation of [3H]proline in vitro.
Oxytocin
had a concentration related inhibitory effect on the labelling with [3H]proline. Addition of indomethacin did not influence the response to
oxytocin
indicating that the effect was not directly mediated by prostaglandins. Oestradiol-17 beta potentiated the effect of
oxytocin
.
Vasopressin decreased
the incorporation of [3H]proline slightly but the action of this hormone was significantly less than that of
oxytocin
. The results suggest that
oxytocin
under in vitro experimental conditions influences cervical connective tissue metabolism which is in contrast to current clinical experiences.
...
PMID:Effects of oxytocin on cervical and uterine connective tissue. 673 Aug 60
