Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P01178 (oxytocin)
 15,767 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

76 therapeutic abortions and 16 labors for missed abortion were induced by extraamniotic isotonic saline with or without oxytocin. Saline was perfused with a Number 16 or 18 Foley catheter, just inside the cervical os, at 16 drops/minute. After 2 hours oxytocin was infused iv if needed. A 2nd saline perfusion was given in some cases. Uterine contractions started in 15-30 minutes; mean time to abortion ranged from 5 to 50 hours; mean time to delivery of the macerated fetus was 7 hours, 45 minutes. This method was remarkably safe, with no complications, even in patients with hemolytic anemia, Caesarean section scars, fibroids, and a 10-week pregnancy. it would be appropriate when hypertonic saline or prostaglandins are contraindicated, such as in renal, cardiac, or respiratory disease, when coagulation disorders are likely, when the amniotic sac is difficult to puncture, and when a fetus in good condition is needed for genetic or embryologic studies.
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PMID:[Indications of choice for extra-amniotic perfusion of physiologic serum]. 95 36