Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P00790 (PGA)
 2,475 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Experimental data now strongly suggest that the PGs, by nature of their natural local occurrence and destruction, powerful effects on, and release from lung tissue are important in regulating both pulmonary homeostasis and dysfunction. Laboratory studies on their activity, potency, duration, preferred route of administration, mechanism and possible antiallergic effects, have been largely substantiated in humans. Structure activity studies on a large number of congeners of PGE, PGF, and PGA emphasize the critical importance of stereochemistry and various substituent groups on biologic activity in the lung.
Adv Prostaglandin Thromboxane Res 1976
PMID:Actions of prostaglandins on the respiratory tract of animals. 82 48